Comments
Description
Transcript
Yun Liu
Yun Liu National Institute of Standards and Technology Center for Neutron Research University of Delaware Department of Chemical & Biomolecular Engineering 100 Bureau Drive MS 6102 150 Academy Street, Colburn Lab Gaithersburg, MD, 20899 USA Newark, DE, 19716, USA Phone: (301) 975-6235, Fax: (301) 921-9847 E-mail: [email protected], [email protected] Website: http://www.nist.gov/ncnr/yunliu.cfm ResearchID at Web of Science: http://www.researcherid.com/rid/F-6516-2012 RESEARCH INTERESTS: • • • Neutron and X-ray scattering techniques. Structure and dynamics of colloidal systems, such as nucleation/clusterization in colloidal and biological molecular assembly systems, ion/counterion association in polyelectrolyte solution, colloidal interactions, structure and viscosity relation, gelation and glass transitions. Interaction of small molecules on the surface or in porous media, such as hydrogen storage, green-house gas capture, molecular recognition based on surface selection, molecular sieving, small molecule dynamics on functionalized surfaces. EDUCATION: Sep. 1999Aug. 2005 Ph. D. of Nuclear Science and Engineering, M.S. in Nuclear Engineering Nuclear Science and Engineering Department, MIT, USA Cumulative Graduate GPA: 4.9/5.0 Sep. 1997Jul. 1999 Master of Nuclear Technology & Application Engineering Physics Department, Tsinghua University, P. R. China Sep. 1993Jul. 1997 Bachelor of Engineering Physics Engineering Physics Department, Tsinghua University, P. R. China EMPLOYMENT EXPERIENCE: 2009201420142011-2014 2010-2011 2009-2010 2005-2008 2005-2008 1999-2005 Staff Scientist in SANS/USANS team, NIST Center for Neutron Research. Research Associate Professor at Department of Chemical & Biomolecular Engineering, University of Delaware. Affiliated faculty in Department of Physics and Astronomy, University of Delaware Research Assistant Professor at Department of Chemical & Biomolecular Engineering, University of Delaware. Senior Scientist at Department of Chemical Engineering, University of Delaware. Research Scientist at Department of Chemical Engineering, University of Delaware. Guest Researcher, NIST Center for Neutron Research. Research Associate, Dept. of Materials Science and Engineering, University of Maryland, College Park. Research Assistant, Nuclear Science and Engineering Department, MIT 1/18 SCHOLARSHIPS AND AWARDS: • • • • • • • • • • • • • Neutron Scattering Society of America Science Prize for “the discovery of dynamic cluster ordering in complex colloidal and protein systems using neutron scattering” (2016). Distinguished referee of The European Physical Journal (2015). Katharine B. Gebbie Young Scientist Award by NIST-Sigma Xi for “the contributions to the field of soft matter, in particular, to fundamental colloid science and its application to biopharmaceutical science” (2014). NIST chapter of Sigma Xi’s 2008 outstanding poster award (2008). Shanghai Laser Award for Research Achievement, Nuclear Science and Engineering Department, MIT (2005). Presidential Fellowship, MIT (Summer, 2002). Graduate Fellowship, MIT (Summer, 2001 – Summer, 2002). Outstanding Performance Graduate Student, Nuclear Science and Engineering Department, MIT (2000). Title of “Excellent Graduate”, Tsinghua University (1997). Highest Scholarship Award, Tsinghua University (1996-1997). This award is regarded as the most honorable university-wide award and is awarded to less than ten out of about ten thousand students each year. Excellent Student of Beijing’s Universities and “Sonny” Scholarship (1995-1996). “Nanxiang Jiang” Scholarship, Tsinghua University (1994-1995). First Class Prize of “Excellent Student of Tsinghua University” (1993-1994). GRANTS: • • • • • • • Developing Measurements of Structure-Property Relationships in Complex Fluids in Extreme Environments, IMS grant approved by NIST, PI on the flow of complex fluid in porous media which is one of three proposed directions, 2014-2019, (total budget of this IMS grant is about ≈$5,000,000). In-Situ Visualization of Water Transport & Distribution in Photovoltaic Modules using Neutron Imaging, PI, Project with NIST, 2014-2015 ($50,000) Neutron Scattering Studies of monoclonal antibody and surfactant solutions, PI, Project with Genentech Inc., 2014-present. ($25,000/year) Neutron Scattering Investigation of Unconventional Shale Gas; PI; Project with Aramco Service Company; 2014-2017. ($450,000) Investigation of protein cluster formation; Project with Genentech Inc., PI: Yun Liu and Norman J. Wagner, 2010-2014 ($260,000) A Study of Real-Space Neutron Scattering Methods; LDRD Director’s Fund of Oak Ridge National Laboratory; co-PI. PI: J. Lee Robertson. 2009-2010 ($500,000) An Experimental, Theoretical and Molecular Modeling Approach to Characterize the Structure and Dynamics of Charged PAMAM Dendrimers in Solution; LDRD Director’s Fund of Oak Ridge National Laboratory; co-PI. PI: Wei-Ren Chen. 2008-2009 ($600,000) SERVICE: • • • Advisory Board Member for 4th Protein-Protein Interaction Conference, October, 2016 Co-organizer for the focus session on “Clustering and gelation with competing interactions” in APS National March Meeting at Baltimore, 2016. Session chair of MRS meeting on “Glassy Soft Materials”, Boston, December, 2015. 2/18 • • • • • • • • • • • • • • • • • Co-organizer for a workshop at MIT about “Topics in Soft Condensed Matter”, Boston, November, 2015. Discussion leader of “Dynamics in soft matter, glasses, gels, transport in soft matter, and active soft matter” session for the Second Target Station (STS) workshop at Spallation Neutron Source (SNS), ORNL, October, 2015 Session Chair/Moderator for 3rd Protein-Protein Interaction Conference at Boston in October, 2015. Co-organizer of the workshop on “Structure and Dynamics of Soft Matter Systems” at CNMS in ORNL in September, 2015 Member of International Advisory Committee for the workshop on “Applications and the Future Directions of Neutron Spin-Echo in Soft/Hard Condensed Matter” at Oak Ridge National Laboratory in May, 2015. Co-Chair of the Summer School on Methods and Applications of Neutron Spectroscopy at NIST in June, 2015. Member of “Soft Matter” program committee for 7th ACNS (American Conference on Neutron Scattering), Knoxville, Tennessee, 2014. Member of the Editorial Board for the journal, “Chemical Engineering & Process Techniques” since 2013. Organizer for “Frontier of selective-structure characterization in complex soft matter materials” at Annual Meeting for American Crystallographic Association (ACA) at Albuquerque, New Mexico, USA in 2014. Lead organizer and session chair for the symposium of “Charged Colloids with Short-range Attractions” for American Physical Society National March Meeting at Baltimore, MD in 2013. Session chair for Complex Fluids and Gels for American Conference on Neutron Scattering, June 24-28, Georgetown University, Washington DC, 2012 Session chair for Biocolloids V for 86th ACS Colloid & Surface Science Symposium at Johns Hopkins University, June 10-13, 2012 Lead organizer for the 8th Middle Atlantic Soft Matter Workshop at National Institute of Standards and Technology, Maryland on December 9, 2011 Reviewer for the Neutron Scattering Section of CPHS at Tsinghua University, Beijing, China, in June, 2011 Member of the international advisory committee of Compact Pulsed Hadron Sources (CPHS) at Tsinghua University, China, June, 2009. Organizer of a tutorial session of American Conference on Neutron Scattering, Santa Fe, NM, May 11-15, 2008. Symposium co-organizer and session chair of the HH Symposium entitled “The Hydrogen Economy” at the Materials Research Society National Meeting in San Francisco, Mar. 24-28, 2008. TEACHING EXPERIENCE: Spring 2016 Oct. 2010 Principle instructor for a graduate course of the spring semester at the Engineering School of University of Maryland at College Park. ENMA633: Advanced Characterization of Soft Matter Materials Lecture in a course at Chemical Engineering Department, University of Delaware CHEG 867: Scattering Methods for Characterizing Soft Condensed Matter 3/18 May 2010 May 2008 Spring 2004 Spring 2003 Spring 2000 Lecture in NCNR/NSF Summer School on the Fundamentals of Neutron Scattering, National Institute of Standards and Technology, Gaithersburg, Maryland Tutorial session lecture for 2008 ACNS, Santa Fe, NM. Colloidal Interaction in Solution Teaching Assistant, Nuclear Science and Engineering Department, MIT, USA Statistical thermodynamics of complex liquids. (Course 10.44J, 22.52J, 8.575J) Teaching Assistant, Nuclear Science and Engineering Department, MIT, USA Interaction of radiation with matter. (Course 22.51) Teaching Assistant, Nuclear Science and Engineering Department, MIT, USA A hands-on introduction to nuclear magnetic resonance. (Course 22.920) JOURNAL/GRANT REVIEWER: Journal of American Chemical Society, Physical Review Letters, Physical Review B, Physical Review E, Langmuir, Soft Matter, Journal of Physical Chemistry, Journal of Physical Chemistry Letters, Chemical Physics Letters, Chemistry of Materials, Journal of Physics Condensed Matter, Journal of Alloys and Compounds, International Journal of Thermophysics, Materials Science and Engineering C, International Journal of Modern Physics B., Reviewer for National Science Foundation and Basic Energy of Science of DOE. MEMBERSHIP: Neutron Scattering Society of America, American Physical Society, Material Research Society, American Chemical Society UNDERGRADUATE, GRADUATE AND POSTDOC ADVISEES: Graduate: • Jannatun Nayem, University of Delaware, (2014-present) • Zhiyuan Wang, Tsinghua University, China, (2015-present) • Jie Chen, Tsinghua University, China (2012-2016) • Douglas Godfrin, University of Delaware, (2010-2015) • Dr. Nestor E. Valadez Perez, University of Guanajuato, Mexico (2012-2014) • Dr. Jung Min Kim, University of Delaware, (2009-2012) • Dr. Tianfu Li, Chinese Institute of Atomic Energy, China (2007-2011) • Dr. Xin Li, Rensselaer Polytechnic Institute, (2008 – 2011) Postdoc: • Dr. Zhenhuan Zhang, University of Delaware (2016-present) • Dr. Hongyu Guo, University of Delaware (2015-present) • Dr. Wei-Shan Chiang, University of Delaware (2014-present) • Dr. Christopher E. Bertrand, National Institute of Standards and Technology (2013-2015) • Dr. Eric Yearley, University of Delaware, (2010 – 2012) • Dr. Jiang Du, Institute of Chemistry, Chinese Academy of Science, China (2008-2009) Undergraduate: • Katherine E. Borner, Chemistry Department, University of Texas at Dallas, USA (Summer, 2013) • Michelle Reele, Chemical Engineering Department, SUNY Buffalo, USA (Summer, 2012) • Navjot Kaur, The City College of New York, NY, USA (Summer, 2010) • Aaron Aziz, Chemical Engineering Department, University of Maryland, USA (Summer, 2009) 4/18 TECHNICAL SKILLS: Expert in neutron scattering, inelastic X-ray scattering instrument, X-ray photon correlation spectroscopy, Dynamic light scattering, small angle X-ray scattering. Expert in Nuclear Magnetic Resonance Spectrometers (NMR) Experienced with wide range of volumetric gas loading and treatment apparatus Experienced programmer (C, C++, Matlab, Python, Java, FORTRAN, UNIX scripting) Lab computer administrator for over 20 computers (Linux, Unix, DOS/Windows) from 2001 to 2002. Maintained computer networks, 7 SGI stations controlling NMR machines, two file servers, and two gateways. ACADEMIC PUBLICATIONS: (ISI Web of Science. Total citations: 3654. Citations in 2014 alone: 580. H-index=27.) (Google scholar search. Total citations: 4253. H-index=28.) (Data taken as of Oct. 29, 2015) Ph.D. Dissertation, MIT Studies of Structure and Dynamics of Biological Macro-molecular Assemblies by Low Angle Neutron Diffraction and Inelastic X-ray Scattering, MIT, Defended on August 3, 2005. M. S. Thesis, MIT Characterizing Porous Media by Diffusive-MASS NMR Journal Papers Published and in Press (*: corresponding author, total 97 peer-reviewed publications.) 1) V. L. Dharmaraj, P. Douglas Godfrin, Yun Liu, Steven D. Hudson, “Rheology of Clustering Protein Solutions”, Biomicrofluidics, 10(4), 043509(2016). 5/18 2) Clinton G. Wiener, Madhusudan Tyagi, Yun Liu, R. A. Weiss, Bryan D. Vogt, “Spramolecular Hydrophobic Aggregates in Hydrogels Partially Inhibit Ice Formation”, J. of Phys. Chem. B, accepted, (2016) 3) Carlos R. López-Barrón, Peter J. Beltramo, Yun Liu, Sung-Min Choi, Min-Jae Lee, “Mechanical, Dielectric and Structural Characterization of Cross-Linked PEG-Diacrylate/Ethylammonium Nitrate Ionogels”, Polymer, 87, 300-307 (2016). 4) Wei-Shan Chiang, Emiliano Fratini, Piero Baglioni, Daniel Georgi, Jin-hong Chen*, Yun Liu*, “Methane Adsorption in Model Mesoporous Material, SBA-15, Studied by Small Angle Neutron Scattering”, J. Physical Chemistry C, 120,4354-4363 (2016). 5) P. Douglas Godfrin, Jonathan Zarzar, Isidro Zarraga*, Lionel Porcar, Peter Falus, Norman J. Wagner, Yun Liu*, “The Effect of Hierarchical Cluster Formation on the Viscosity of Concentrated Monoclonal Antibody Formulations Studied by Neutron Scattering”, J. Phys. Chem. B, 120, 278-291 (2016) 6) Gregory Barnett, Wei Qi, Samiul Amin, Edgar Lewis, Vladimir Razinkov, Bruce Kerwin, Yun Liu, Christopher Roberts, “Structure Changes and Aggregation Mechanisms for Anti-streptavidin IgG1 at Elevated Concentration”, J. Phys. Chem. B, 119,15150-15163 (2015). 7) P. Douglas Godfrin, Steven D. Hudson, Kunlun Hong, Lionel Porcar, Peter Falus, Norman J. Wagner*, Yun Liu*, “Short-time glassy dynamics in viscous protein solutions with competing interactions”, Phys. Rev. Lett., 115, 228302 (2015). 8) Christopher E. Bertrand, P. Douglas Godfrin, Yun Liu*, “Direct observation of critical adsorption on colloidal particles”, J. of Chem. Phys.143, 084704 (2015). 9) Zhe Wang, Kanae Ito, Juscelino Leao, Leland Harriger, Yun Liu, Sow-Hsin Chen, “The liquidliquid phase transition and its phase diagram in deeply-cooled heavy water confined in a nanoporous silica matrix”, Journal of Physical Chemistry Letters 6, 2009-2014(2015) 10) Jie Chen, Steven Kline, Yun Liu*, “From the depletion attraction to the bridging attraction: the effect of solvent molecules on the effective colloidal interactions”, J. of Chem. Phys., 142, 084904 (2015). 11) Junhua Luo, Guangcui Yuan, Chuanzhuang Zhao, Charles C. Han, Jie Chen, Yun Liu, “Gelation of large hard particles with short-range attraction induced by bridging of small soft microgels”, Soft Matter, 11,2494-2503(2015) 12) Christopher E. Bertrand, Yun Liu*, “Molecular dynamics of a model dimerizing fluid”, J. Chemical Physics, 142, 044503(2015). 13) Hao Shen, Néstor E. Valadez_Pérez, Brett Guralnick, Yun Liu, and Michael E. Mackay, “Performance enhancement of polymer-based solar cells by induced phase-separation with silica particles”, J. of Materials Chemistry, 2,10087-10110 (2014) 14) Xin Li, Changwoo Do, Yun Liu, Luis Sánchez-Diáz, Gregory Smith, Wei-Ren Chen, “A scattering function of star polymers including excluded volume effects”, J. of Applied Cyrstallography 47, 1-25(2014). 15) Rachel Pollock, Jae-Hyuk Her, Craig Brown, Yun Liu, Anne Dailly, “Kinetic Trapping of D2 in MIL-53(AL) Observed using Neutron Scattering”, J. Physical Chemistry C, 118, 1819718206(2014). 6/18 16) P. Douglas Godfrin, Néstor E. Valadez-Pérez, Ramón Castañeda-Priego, Norman J. Wagner*, Yun Liu*, “Generalized phase behavior of cluster formation in colloidal dispersions with competing interactions”, Soft Matter, 10(28), 5061-5071(2014). 17) Xin Li, Lionel Porcar, Luis E. Sanchez-Diaz, Changwoo Do, Yun Liu, Tae-Hwan Kim, Gregory S. Smith, William A. Hamilton, Kunlun Hong, Wei-Ren Chen, “Influence of Molecular Solvation on the Conformation of Star Polymers”, ACS Macro. Lett., 3, 458-461(2014) 18) Eric J. Yearley, Paul D. Godfrin, Tatiana Perevozchikova, Hailiang Zhang, Peter Falus, Lionel Porcar, Michihiro Nagao, Joseph E. Curtis, Pradad Gawande, Rosalynn Taing, Isidro E. Zarraga*, Norman J. Wagner, Yun Liu*, “Observation of small cluster formation in concentrated monoclonal antibody solutions and its implications to solution viscosity” Biophysical Journal, 106(8), 1763-1770 (2014) Ranked in the top 1% of highly cited paper in the academic field of Biology & Biochemistry from the ISI Web of Science as of February 2015. Press report by Chemical & Engineering News “Why Monoclonal Antibody Drugs Get Sticky” Press report by the Department of Commerce, USA “NIST Research Offers Guide in Formulating Cancer Treatment Drugs” Press report by National Institute of Standards and Technology “NIST Helps Cancer Treatment Drugs Get Past Their Sticking Point” Press report by Institut Laue-Langevin in France “Neutron beams reveal how antibodies cluster in solution” Selected to Scientific Highlight at NIST Center for Neutron Research “Direct observation of small reversible clusters in concentrated monoclonal antibody solutions” Selected to Scientific Highlight at Institut Laue-Langevin in France, “Observing protein cluster phase in concentrated monoclonal antibody solutions” 19) Néstor E. Valadez-Pérez, Yun Liu, Aaron P. R. Eberle, Norman J. Wagner, Ramón CastañedaPriego, “Dynamical arrest in adhesive hard-sphere dispersions driven by rigidity percolation”, Physical Review E, 88, 060302 (2013). 20) Yun Liu*, “Colloidal systems with both a short-range attraction and a long-range repulsion”, Chemical Engineering & Process Techniques 1(2), 1010 (2013). (An invited perspective article about colloidal systems with competing interactions.) 21) Néstor E. Valadez-Pérez, Ramón Castañeda-Priego, Yun Liu*, “Percolation in colloidal systems with competing interactions: the role of long-range repulsion”, RSC Advances 3, 25110-25119 (2013). 22) Paul Douglas Godfrin, Ramón Castañeda-Priego, Yun Liu, Norman J. Wagner, “Intermediate range order and structure in colloidal dispersions with competing interactions”, J. Chem. Phys. 139, 154904 (2013). 23) Eric J. Yearley, Isidro E. Zarraga*, Steven J. Shire, Thomas M. Scherer, Yatin Gokarn, Norman J. Wagner, Yun Liu*, “Small-Angle Neutron Scattering Characterization of Monoclonal Antibody Conformations and Interactions at High Concentrations”, Biophysical Journal, 105, 720731(2013). 7/18 24) Ali Qajar, Maryam Peer, Ramakrishnan Rajagopalan, Yun Liu, Craig Brown, Henry C. Foley, “Surface compression of light adsorbates inside microporous PFA-derived carbons” Carbon, 60, 538-549(2013). 25) Bin Wu, Yun Liu*, Xin Li, Eugene Mamontov, Alexander I. Kolesnikov, Souleymane O. Diallo, Changwoo Do, Lionel Porcar, Kunlun Hong, Sean C. Smith, Li Liu, Gregory S. Smith, Takeshi Egami, Wei-Ren Chen*, “Charge-Dependent Dynamics of a Polyelectrolyte Dendrimer and Its Correlation with Invasive Water”, J. of the American Chemistry Society 135(13), 5111-5117 (2013). 26) Baoshan Huang, Yang Zhang, Xiang Shu, Yun Liu, Dayakar Penumadu, X. Philip Ye, “Neutron Scattering for Moisture Detection in Foamed Asphalt”, Journal of Materials in Civil Engineering, 25(7), 932-938 (2013). 27) Y. Liu*, C. M. Brown, D. A. Neumann, D. B. Geohegan, A. A. Puretzky, C. M. Rouleau, H. Hu, D. Styers-Barnett, P. O. Krasnov, B. I. Yakobson, “Metal-assisted hydrogen storage on Ptdecorated single-walled carbon nanohorns”, Carbon 50, 4953-4964(2012). 28) C. Y. Shew, C. Do, K. Hong, Y. Liu, L. Porcar, G. Smith, W. R. Chen, “Conformational effect on small angle neutron scattering behavior of interacting polyelectrolyte solutions: a perspective of integral equation theory”, J. Chem. Phys. 137, 024907(2012). 29) B. Wu, W. R. Chen, T. Egami, X. Li, Y. Liu, Y. Wang, C. Do, L. Porcar, K. Hong, L. Liu, G. Smith, S. Smith, “Molecular dynamics and neutron scattering study of the dependence of polyeletrolyte dendrimer conformation on counterion behavior”, J. Chem. Phys. 137, 064902 (2012). 30) B. Wu, B. Kerkeni, T. Egami, C. Do, Y. Liu, Y.M. Wang, L. Porcar, K. L. Hong, S. C. Smith, E. L. Liu, G. S. Smith, W. R. Chen, “Structured water in polyelectrolyte dendrimers: Understanding small angle neutron scattering results through atomistic simulation”, J. Chem. Phys. 136, 144901 (2012). 31) P. Falus, L. Porcar, E. Fratini, W. R. Chen, A. Faraone, K. Hong, P. Baglioni, Y. Liu*, “Distinguishing the monomer to cluster phase transition in concentrated lysozyme solutions by studying the temperature dependence of the short-time dynamics”, J. Phys. Condensed Matter 24, 064114(2012). 32) Xin Li, Bin Wu, Yun Liu, Roger Pynn, Chwen-Yang Shew, Gregory S. Smith, Kenneth W. Herwig, J. Lee Robertson, Wei-Ren Chen, Li, Liu, “Contrast variation in spin-echo small angle neutron scattering”, J. Phys.: Condens. Matter 24, 064115(2012). 33) Kunlun Hong, Yun Liu, Lionel Porcar, Dazhi Liu, Carrie Y. Gao, Gregory S. Smith, Kenneth W. Herwig, Sheng Cai, Xin Li, Bin Wu, Wei-Ren Chen, Li Liu , “Structural response of polyelectrolyte dendrimer towards molecular protonation: the inconsistency revealed by SANS and NMR”, J. Phys.: Condens. Matter 24, 064116 (2012). 34) Bin Wu, Xin Li, Changwoo Do, Tae-Hwan Kim, Chwen-Yang Shew, Yun Liu, Jun Yang, Kunlun Hong, Lionel Porcar, Chun-Yu Chen, Emily L. Liu, Gregory S. Smith, Kenneth W. Herwig, Wei-Ren Chen, “Spatial distribution of intra-molecular water and polymeric components in polyelectrolyte dendrimers revaled by small angle scattering investigations”, J. Chem. Phys. 135, 144903 (2011). 35) Cheng-Si Tsao, Yun Liu, Haw-Yeu Chuang, Huan-Hsiung Tseng, Tsan-Yao Chen, Chien-Hung Chen, Ming-Sheng Yu, Qixiu Li, Angela Lueking, Sow-Hsin Chen, “Hydrogen Spillover Effect of 8/18 Pt-Doped Activated Carbon Studied by Inelastic Neutron Scattering”, J. Phys. Chem. Lett. 2, 2322 (2011). (Highlighted by MIT News: “Findings could lead to better hydrogen storage” on Sep. 19, 2011. The link: http://web.mit.edu/newsoffice/2011/better-hydrogen-storage-0919.html ) 36) W. Chen, T. Xu, F. He, W. Wang, C. Wang, J. Strzalka, Y. Liu, J. Wen, D. Miller, J. Chen, K. Hong, L. Yu, S. Darling, “Hierarchical Nanomorphologies Promote Exciton Dissociation in Polymer: Fullerene Bulk Heterojunction Solar Cells”, Nano 11, 3707-3713 (2011). (Highlighted by Argonne National Laboratory of DOE in an article titled as “rethinking the idealized morphology in high-performance organic photovoltaics” in September, 2011. The link is http://www.anl.gov/solar/research/photovoltaic/ideal_morphology.html) 37) E. W. Huang, Y. Liu, Y. Ren, L. Porcar, J. J. Kai, P. K. Liaw, G. S. Smith, W. R. Chen, “Evolution of microstructure in a nickel-based superalloy as a function of aging time”, Philosophical Magazine Letters 91(7), 483-490 (2011). 38) A. G. Richter, S. A. Dergunov, B. Ganus, Z. Thomas, S. V. Pingali, V. Urban, Y. Liu, L. Porcar, E. Pinkhassik, “Scattering Studies of Hydrophobic Monomers in Liposomal Bilayers: An Expanding Shell Model of Monomer Distribution”, Langmuir 27, 3792-3797 (2011). 39) V. Peterson, C. M. Brown, Y. Liu, K. J. Cameron, “Structural Study of D2 within the Trimodal Pore System of a Metal Organic Framework”, J. Phys. Chem. C 115, 8851-8857 (2011). 40) A. Chuang, Y. Liu, T. J. Udovic, P. K. Liaw, G. P. Yu, J. H. Huang, “Inelastic neutron scattering study of hydrogenated (Zr55Cu30Ni5Al10)99Y1 bulk metallic glass”, Phys. Rev. B. 83(17), 174206 (2011). 41) F. He, W. Wang, W. Chen, T. Xu, S. B. Darling, J. Strzalka, Y. Liu, L. Yu, “Tetrathienoanthracene-based Copolymers for Efficient Solar Cells”, J. of the American Chemical Society 133, 3284-3287 (2011). 42) J. M. Kim, R. Castaneda-Priego, Y. Liu, N. J. Wagner “On the importance of thermodynamic self-consistency for calculating stable clusters in hard-core double Yukawa fluids” J. Chem. Phys. 134, 064904 (2011). 43) X. Li, C. Y. Shew, Y. Liu, R. Pynn, L. Liu, K. Herwig, G. Smith, L. Robertson, W. R. Chen, “Prospect for characterizing interacting soft colloidal structures using spin-echo small angle neutron scattering”, J. Chem. Phys. 134, 094504 (2011). 44) Y. Liu*, L. Porcar, J. Chen, W. R. Chen, P. Falus, A. Faraone, E. Fratini, K. Hong, P. Baglioni, “Lysozyme Protein Solution with an Intermediate Range Order Structure” J. Phys. Chem. B 115, 7238-7247(2011). • An invited article for the special issue, “Clusters in Complex Fluids”, in J. Phys. Chem. B. • Selected to Scientific Highlights of Institut Laue-Langevin, France. 45) Y. Yang, C. M. Brown, C. Zhao, A. L. Chaffee, B. Nick, D. Zhao, P. A. Webley, J. Schalch, J. M. Simmons, Y. Liu, J. H. Her, C. E. Buckley, D. A. Sheppard, “Micro-Channel Development and Hydrogen Adsorption Properties in Templated Microporous Carbons Containing Platinum Nanoparticles” Carbon 49, 1305 (2011). 9/18 46) X. Li, M. Zamponi, K. Hong, L. Porcar, C. Y. Shew, T. Jenkins, E. Liu, G. S. Smith, K. W. Herwig, Y. Liu*, W. R. Chen*, “pH Responsiveness of Polyelectrolyte Dendrimers: A Dynamical Perspective” Soft Matter 7, 618(2011). 47) X. Li, K. L. Hong, Y. Liu, C. Y. Shew, E. Liu, K. W. Herwig, G. S. Smith, J. P. Zhao, G. Z. Zhang, S. Pispas, W. R. Chen, “Water distributions in polystyrene-block-poly[Styrenepoly(ethylene oxide)] block grafted copolymer system in aqueous solutions revealed by contrast variation small angle neutron scattering study”, J. of Chem. Phys. 133, 144912 (2010). 48) C. S. Tsao, Y. Liu, M. D. Li, Y. Zhang, J. B. Leao, H. W. Chang, M. S. Yu, S. H. Chen, “Neutron Scattering Methodology for Absolute Measurement of room-Temperature Hydrogen Storage Capacity and Evidence for Spillover Effect in a Pt-Doped Activated Carbon” J. of Physical Chemistry Letters 1, 1569 (2010). 49) X. Li, C. Y. Shew, Y. Liu, R. Pynn, E. Liu, K. W. Herwig, G. S. Smith, J. L. Robertson, W. R. Chen, “Theoretical Studies on the Structure of Interacting Colloidal Suspensions by Spin-echo Small Angle Neutron Scattering”, J. Chem. Phys. 132, 174509 (2010). 50) Y. Liu, C. Y. Chen, H. L. Chen, K. L. Hong, C. Y. Shew, X. Li, L. Liu, Y. B. Melnichenko, G. S. Smith, K. W. Herwig, L. Porcar, W. R. Chen, “Electrostatic Swelling and Conformational Variation Observed in High-Generation Polyelectrolyte Dendrimers”, J. of Physical Chemistry Letters 1, 2020 (2010). 51) S. Xiang, W. Zhou, Z. Zhang, M. A. Green, Y. Liu*, B. Chen*, “Open Metal Sites within Isostructural Metal-Organic Frameworks for Differential Recongnition of Acetylene and Extraordinarily High Acetylene Storage at Room Temperature” Angewandte Chemie International Edition 49, 4615 (2010). 52) Y. Liu, L. Porcar, K. Hong, C. Y. Shew, X. Li, E. Liu, P. D. Butler, K. W. Herwig, G. S. Smith, W. R. Chen, “Effect of Counterion Valence on the pH Responsiveness of Polyamidomaine Dendrimer Structure” J. Chem. Phys. 132, 124901 (2010). 53) H. Wu, J. M. Simmons, Y. Liu, C. M. Brown, X. S. Wang, S. Ma, V. K. Peterson, P. D. Southon, C. J. Kepert, H. C. Zhou, T. Yildirim, W. Zhou, “Metal-Organic Frameworks with Exceptionally High Methane Uptake: Where and How is Methane Stored?” Chemistry: A European Journal 16, 5205(2010). 54) L. Porcar, K. Hong, P. D. Butler, K. W. Herwig, G. S. Smith, Y. Liu*, W. R. Chen*, “Intramolecular Structural Change of PAMAM Dendrimers in Aqueous Solutions Revealed by Small-Angle Neutron Scattering” J. Phys. Chem. B 114, 1751-1756 (2010). 55) L. Porcar, P. Falus, W. R. Chen, A. Faraone, E. Fratini, K. Hong, P. Baglioni, Y. Liu*, “Formation of the Dynamic Clusters in Concentrated Lysozyme Protein Solutions”, J. of Physical Chemistry Letters 1, 126-129 (2010). Selected to Scientific Highlights of Institut Laue-Langevin, France 56) S. Xiang, W. Zhou, J. M. Gallegos, Y. Liu*, B. Chen*, “Exceptionally High Acetylene Uptake in a Microporous Metal-Organic Framework with Open Metal Sites”, J. of the American Chemical Society 131, 12415-12419 (2009). (Highlighted by NIST Tech Beat, Aug. 25, 2009. Reported by many websites worldwide. http://www.nist.gov/ncnr/acetylene_082509.cfmHH. “Safer, Denser Acetylene Storage in an Organic Framework”) 10/18 57) M. Xue, Y. Liu, R. M. Schaffino, S. Xiang, X. Zhao, G. S. Zhu, B. Chen, “New Prototype IRMOF Zn4O(FMA)3 Exhibiting High Gas Storage”, Inorg. Chem. 48 (11), 4649-4651 (2009). 58) C. I. Contescu, C. M. Brown, Y. Liu, V. V. Bhat, N. C. Gallego, “Detection of Hydrogen Spillover in Palladium-modified Activated Carbon Fibers During Hydrogen Adsorption”, J. Phys. Chem. C 113, 5886-5890 (2009). 59) C. M. Brown, Y. Liu, T. Yildirim, V. K. Peterson, C. J. Kepert, “Hydrogen Adsorption in HKUST-1: a Combined Inelastic Neutron Scattering and First-principle Study”, Nanotechnology, 20, 204025, (2009). 60) E. W. Huang, P. K. Liaw, L. Porcar, Y. Liu, Y. L. Liu, J. J. Kai, W. R. Chen, “Study NanoPrecipitates Using Small Angle Neutron Scattering”, Applied Physics Letters 93, 161904 (2008). 61) T. Li, K. Hong, L. Porcar, R. Verduzco, P. D. Butler, G. S. Smith, Y. Liu*, W. R. Chen*, “Assessing the Intra-molecular Cavity of a PAMAM Dendrimer in Aqueous Solutions by Small Angle Neutron Scattering”, Macromolecules 41(22), 8916-8920 (2008). 62) L. Porcar, Y. Liu, R. Verduzco, K. Hong, P. D. Butler, L. J. Magid, W. R. Chen, “Structural Investigation of PAMAM Dendrimers in Aqueous Solutions Using Small-Angle Neutron Scattering: Effect of Generation”, J. of Physical Chemistry B 112(47), 14772-14778 (2008). 63) Y. Liu*, J. Her, A. Dailly, A. J. Ramirez-Cuesta, D. A. Neumann, C. M. Brown*, “Reversible Structure Transition in MIL-53 with Large Temperature Hysteresis”, J. of the American Chemical Society 130, 11813-11818 (2008). 64) J. Luo, H. Xu, Y. Liu, Y. Zhao, L. L. Daemen, C. M. Brown, T. V. Timofeeva, S. Ma, H. C. Zhou, “Hydrogen Adsorption in a Highly Stable Porous Rare-Earth Metal-Organic Framework: Sorption Properties and Neutron Diffraction Studies”, J. of the American Chemical Society 130, 9626 (2008). 65) Y. Liu, H. Kabbour, C. M. Brown, D. A. Neumann, C. C. Ahn, “Increasing the Density of Adsorbed Hydrogen with Coordinatively Unsaturated Metal Centers in Metal-organic Frameworks”, Langmuir 24, 4772 (2008). • Highlighted by NIST Tech Beat, Apr. 1, 2008. Reported by numerous websites worldwide. http://www.nist.gov/ncnr/hydrogen_040108.cfm . “More Solid than Solid: A Potential Hydrogen-Storage Compound”.) • One of five most cited papers published by Langmuir in 2008 (citations till July, 2009). • Selected to NCNR Accomplishments and Opportunities of 2008. 66) D. Liu, Y. Zhang, Y. Liu, J. Wu, C. C. Chen, C. Y. Mou, S. H. Chen, “Density Measurement of 1-D Confined Water by Small Angle Neutron Scattering Method – Pore Size and Hydration Level Dependences”, submitted to J. of Physical Chemistry B 112, 4309 (2008). 67) V. K. Peterson, Y. Liu, C. M. Brown, C. J. Kepert, “Structure Characterization of D2 in Cu3(1,3,5-benzenetricarboxylate)2 Using Neutron Powder Diffraction”, Materials Science Forum 561-565, 1601-1604 (2007). 68) W. R. Chen, L. Porcar, Y. Liu, P. D. Butler, L. J. Magid, “Study the Counterion Effect on the Structural Properties of Charged G4 PAMAM Dendrimer Aqueous Solutions by Small Angle Neutron Scattering”, Macromolecules 40, 5887 (2007). 11/18 69) S. H. Chen, M. Broccio, Y. Liu, E. Fratini, P. Baglioni, “The 2Y Model and its Applications: the Cases of Charged Proteins and Copolymer Micellar Solutions”, J. of Applied Crystallography 40, S321 (2007). 70) Y. Liu, C. M. Brown, J. L. Blackburn, D. A. Neumann, T. Gennett, L. Simpson, P. Parilla, A. C. Dillon, M. J. Heben, “Inelastic Neutron Scattering of H2 Adsorbed in Boron Substituted Single Wall Carbon Nanotubes”, J. of Alloys and Compounds 446-447, 368 (2007). 71) Y. Liu, C. M. Brown, D. A. Neumann, V. K. Peterson, C. Kepert, “Inelastic Neutron Scattering of H2 Adsorbed in HKUST-1”, J. of Alloys and Compounds 446-447, 385 (2007). 72) M. Dinca, W. S. Han, Y. Liu, A. Dailly, C. M. Brown, D. A. Neumann, J. R. Long, “Observation of CuII-H2 Interactions in a Fully-Desolvated, Sodalite-Type Metal-Organic Framework”, Angewandte Chemie International Edition 46, 1419 (2007). 73) M. Dinca, A. Dailly, Y. Liu, C. M. Brown, D. A. Neumann, J. R. Long, “Hydrogen Storage in a Microporous Metal-Organic Framework with Exposed Mn2+ Coordination Sites”, J. of the American Chemical Society 128, 16876 (2006). • Highlighted by Chemical & Engineering News, Vol. 85, 11 (2007). HIt has been cited as “significant milestone in hydrogen storage”. • Ranked as one of Journal of the American Chemical Society’s Hot Papers: Nov. 2007, January, March, and May 2008. • Selected to NCNR Accomplishments and Opportunities of 2006. 74) V. K. Peterson, Y. Liu, C. M. Brown, C. J. Kepert, “Neutron Powder Diffraction Study of D2 Sorption in Cu3(1,3,5-benzenetricarboxylate)2”, J. of the American Chemical Society 128, 15578 (2006). • Highlighted by Chemical & Engineering News, Vol. 85, 11 (2007) HIt has been cited as “significant milestone in hydrogen storage”. 75) M. R. Hartman, V. K. Peterson, Y. Liu, S. S. Kaye, J. R. Long, “Neutron Diffraction and Neutron Vibrational Spectroscopy Studies of Hydrogen Adsorption in the Prussian Blue Analogue Cu3[Co(CN)6]2”, Chemistry of Materials 18 (14), 3321 (2006). 76) Y. Liu, E. Fratini, P. Baglioni, W. R. Chen, L. Porcar, S. H. Chen, “Liu et al. Reply”, Physical Review Letters 96, 219802 (2006). 77) M. Broccio, D. Costa, Y. Liu, and S. H. Chen, “The Structural Properties of a Two-Yukawa Fluid: Simulation and Analytical Results”, J. of Chemical Physics 124, 084501 (2006). 78) Y. Liu, S. H. Chen, D. Berti, P. Baglioni, A. Alatas, H. Sinn, E. Alp, A. Said, “Effects of Counterion Valency on the Damping of Phonons Propagating Along the Axial Direction of Liquid-crystalline DNA”, J. of Chemical Physics 123, 214909 (2005). (Selected for the December 15, 2005 issue of Virtual Journal of Biological Physics Research) 79) Y. Liu, E. Fratini, P. Baglioni, W. R. Chen, S. H. Chen, “An Effective Long-range Attraction Between Protein Molecules in Solutions Studied by Small Angle Neutron Scattering”, Physical Review Letters 95, 118102, (2005). (Selected for the September 15, 2005 issue of Virtual Journal of Biological Physics Research) 80) Y. Liu, D. Berti, P. Baglioni, S. H. Chen, A. Alatas, H. Sinn, A. Said, E. Alp, “Inelastic X-ray Scattering Studies of Phonons Propagating along the Axial Direction of a DNA Molecule Having Different Counter-ion Atmosphere ”, J. of Physics and Chemistry of Solids, 66, 2235 (2005). 12/18 81) Y. Liu*, W. R. Chen, S. H. Chen, “Cluster Formation in Two Yukawa Fluids”, J. of Chemical Physics 122, 044507 (2005). (Selected for the January 15, 2005 issue of Virtual Journal of Biological Physics Research) 82) J. Wu, Y. Liu, W. R. Chen, J. Cao, S. H. Chen, “Structural Arrest Transitions in Fluids Described by Two Yukawa Potentials”, Physical Review E 70, 050401 (2004). 83) W. R. Chen, Y. Liu, F. Mallamace, P. Thiyagarajan, S. H. Chen, “Studies of Structural Arrest Transition in L64/D2O Micellar Solutions”, J. Physics: Condensed Matter 16, S4951 (2004). 84) Y. Liu, D. Berti, A. Faraone, W. R. Chen, A. Alatas, H. Sinn, E. Alp, P. Baglioni, S. H. Chen, “Inelastic X-ray Scattering Studies of Phonons in Liquid Crystalline DNA”, Physical Chemistry Chemical Physics 6 (7), 1499 (2004). 85) G. Leu, Y. Liu, D. D. Werstler, D. G. Cory, “NMR Characterization of Elastomer-Carbon Black Interactions”, Macromolecules 37, 6883 (2004). 86) P. J. Chen, Y. Liu, T. A. Weiss, H. W. Huang, H. Sinn, E. Alp, A. Said, S. H. Chen, “Studies of Short-Wavelength Collective Molecular Motions in Lipid Bilayers Using High Resolution Inelastic X-ray Scattering”, Biophysical Chemistry 105, 721 (2003). 87) P. N. Sen, Y. Liu, G. Leu, D. G. Cory, “A New Probe of Pore Geometry: Diffusive MASS NMR”, Magnetic Resonance Imaging 21, 257, (2003). 88) Y. Liu, G. Leu, S. Singer, P. N. Sen, D. G. Cory, “Selectively Observing the Amplitude Modulation under Magic Angle Sample Spinning”, J. of Chemical Physics 119, 2663, (2003). 89) P. N. Sen, Y. Liu, G. Leu, D. G. Cory, “Detection of Motion through Susceptibility Fields in Two-Dimensional Exchange Diffusive-MASS experiments”, Chemical Physics Letters 366, 588, (2002). 90) Y. Liu, G. Leu, S. Singer, D. G. Cory, P. N. Sen, “Manipulation of Phase and Amplitude Modulation of Spin Magnetization in Magic Angle Spinning Nuclear Magnetic Resonance in the Presence of Molecular Diffusion”, J. Chemical Physics 114, 5729 (2001). Conference Proceedings: 91) L. Porcar, Y. Liu, K. Hong, P. D. butler, E. W. Huang, W. R. Chen, “Counterion Association and Structural Conformation Change of Charged PAMAM Dendrimer in Aqueous Solutions Revealed by Small Angle Neutron Scattering” Macromol. Symp. 279, 65-71 (2009). 92) C. M. Brown, Y. Liu, D. A. Neumann, “Neutron Powder Diffraction of Metal-Organic Frameworks for Hydrogen Storage” PRAMANA Physics Journal 71, 755-760 (2008). 93) C. M. Brown, Y. Liu, W. R. Chen, S. P. Tung, and B. J. Hwang, “Dynamics of Water in a Porous Phosphate Glass”, Proceedings for the 8th International Conference on Quasi-Elastic Neutron Scattering 2006, page 45-50, Published by Materials Research Society, 2007. 94) Y. Liu, C. M. Brown, D. A. Neumann, H. Kabbour, C. C. Ahn, “Hydrogen adsorption in MOF-74 studied by inelastic neutron scattering”, in Life Cycle Analysis for New Energy Conversion and Storage Systems, edited by V. M. Fthenakis, A. C. Dillon, and N. Savage, Materials Research Society Symposium Proceeding 1041E, 1040-R2_03 (2007). (invited) 95) C. M. Brown, Y. Liu, H. Hui, A. A. Puretzky, B. Zhao, C. M. rouleau, D. Styers-Barnett, D. B. Geohegan, “Inelastic Neutron Scattering as a Probe of the States of Hydrogen in Carbon Materials”, 2007 Carbon Conference Proceedings, Seattle (2007). 13/18 96) H. Hu, B. Zhao, A. A. Puretzky, C. M. Rouleau, D. Styers-Barnett, D. B. Geohegan, C. M. Brown, Y. Liu, W. Zhou, H. Kabbour, D. A. Neumann, C. C. Ahn, “Tailoring of Single Carbon Nanohorns for Hydrogen Storage and Catalyst Supports”, 2007 Carbon Conference Proceedings, Seattle (2007). 97) Y. Liu, C. M. Brown, T. B. Baumann, D. A. Neumann, “Applications of Neutron Scattering Techniques to Hydrogen Storage Materials”, Transactions of the American Nuclear Society 97, 319 (2007). (invited) Other publications: 98) E. J. Yearley, P. D.Godfrin, T. Perevozchikova, H. Zhang, P. Falus, L. Porcar, M. Nagao, J. Curtis, P. Gawande, R. Taing, I. E. Zarraga, N. J. Wagner, Y. Liu*, “Direct observation of small reversible clusters in concentrated monoclonal antibody solutions”, Scientific highlights in Annual Report of NCNR (2013). 99) E. J. Yearley, P. D. Godfrin, T. Perevozchikova, H. Zhang, P. Falus, L. Porcar, M. Nagao, J. Curtis, P. Gawande, R. Taing, I. E. Zarraga, N. J. Wagner, Y. Liu*, “Observing protein cluster phase in concentrated monoclonal antibody solutions”, Scientific highlights in Annual Report of ILL (2013) 100) L. Porcar, Y. Liu*, W.R. Chen, K. Hong, P. Falus, A. Faraone, E. Fratini, P. Baglioni, “Dynamic clusters in lysozyme solution” Scientific highlights in Annual Report of ILL, (2010). 101) C. M. Brown, Y. Liu, H. Kabbour, D. A. Neumann, C. C. Ahn, “Denser than solid hydrogen: improving hydrogen storage”, Scientific highlights in Annual Report of NCNR, (2008). 102) M. Dinca, A. Dailly, Y. Liu, C. M. Brown, D. A. Neumann, J. R. Long, “Enhanced hydrogen storage in a microporous metal-organic framework” Scientific highlights in Annual Report of NCNR, (2006). Invited Talks: (48 invited talks at national and international meetings and organizations.) Sep. 2016 German Conference on Neutron Scattering, Kiel, Germany Bridging attraction colloidal system: a model system for some ion specific effects in protein solution Aug. 2016 2nd International Workshop on Matter Out of Equilibrium, Guanajuato, Mexico From the depletion attraction to the bridging attraction: the effect of solvent molecules on the colloidal gelation transition Jul. 2016 American Conference on Neutron Scattering, Los Angeles, CA. (Award winning talk for the Science Prize of Neutron Scattering Society of America) Understanding proteins in solution: Opportunities and challenges for colloidal science and neutron scattering Mar. 2016 Genentech Inc., South San Francisco, CA Applications of neutron scattering techniques to study protein structures and dynamics Feb. 2016 CASSS DC Area Discussion group, Institute of Bioscience and Biotechnology Research, Rockville, MD Studying protein structures in solution by neutron scattering Dec. 2015 Symposium on Liquids and Glassy Soft Materials: Theoretical and Neutron Scattering Studies, MRS Fall Meeting, 2015, Boston, MA The effect of competing interactions on the colloidal glass transition Nov. 2015 The 3rd national conference on neutron scattering and workshop on applications on national neutron facilities, Beijing, China, 2015 14/18 Understanding structure and dynamics of monoclonal antibody solutions at the molecular level using neutron scattering techniques Oct. 2015 Global Technology Community, 3rd Protein-Protein Interaction Conference, Boston, MA Protein-protein interactions and protein clustering in concentrated solutions Oct. 2015 International workshop on the Structure and Dynamics of Supercooled Water and Other Glassy Materials, University of Palermo, Italy. Phase behaviors of colloidal systems with the competing interactions Aug. 2015 7th annual Bioprocessing summit and 4th annual high-concentration protein formulation in Boston, MA Cluster formation in dense protein solutions and its implications to solution viscosity May. 2015 The workshop on “Applications and the Future Directions of Neutron Spin-Echo in Soft/Hard Condensed Matter” at Oak Ridge National Laboratory in May, 2015. Studying dynamics and structures of concentrated protein solutions using neutron spin echo Dec. 2014 1st Advanced Workshop on Out-of-Equilibrium Matter, San Luis Potosí, Mexico. (Invited overview lecture) Investigating the structure and dynamics of soft and biological materials using neutron scattering techniques Dec. 2014 1st Advanced Workshop on Out-of-Equilibrium Matter, San Luis Potosí, Mexico. (Invited scientific talk by Prof. Magdaleno Medina-Noyola) Excess viscous response of protein solutions with glass-like dynamics due to competing potential features Oct. 2014 National Institute of Standards and Technology, Gaithersburg, MD. (Award winning lecture for Katharine B. Gebbie Young Scientist Award of NIST-Sigma Xi) Cluster formation in colloidal and protein solutions with applications in biopharmaceuticals Aug. 2014 Merck Sharp & Dohme Corp., Kenilworth, New Jersey. (Invited by Dr. Ramesh Kashi) Relationship between the cluster formation and the viscosity of concentrated protein solutions Jun. 2014 International Symposium on Frontiers of Technology for the Future: Low Carbon Energy and Life (FoTEL 2014), National Tsing Hua University, Hsinchu Taiwan Solving industrial challenges with neutron scattering techniques Apr. 2014 Department of Materials Science and Engineering, Pennsylvania State University at University Park, PA. (Invited by Prof. Ralph Colby) Understanding protein clusters in concentrated solutions Apr. 2014 Department of Physics & Astronomy, University of Delaware. (Invited by Prof. Edmund Nowak) Protein clusters in concentrated solutions: the concept, the characterization, and the consequence Mar. 2014 Workshop on Neutron Day at University of Delaware, Newark, USA Cluster formation in concentrated protein solutions: implications for protein formulation Jan. 2014 Bimolecular Interaction Technologies Center (BITC) Workshop on Concentrated mAb solutions at Amgen Inc., Thousand Oaks, California, USA Observation of reversible cluster formation in concentrated protein solutions and its effect on solution viscosity Aug. 2013 International Materials Research Congress at Cancun, Mexico Understanding concentrated protein solutions with competing potential features Jul. 2013 National Academies NCNR Review, Gaithersburg, MD, USA 15/18 Microstructural origin of anomalously high viscosity in concentrated monoclonal antibody solutions revealed by neutron spin echo. May 2013 European Spallation Source at Lund, Sweden. (Invited by Dr. Andrew Jackson) Adsorption of small molecules in porous materials: from metal-organic frameworks to colloidal particles with open structure May 2013 Neutrons and Life Science, at Lund, Sweden (Co-organized by European Spallation Sources) Neutron Scattering Studies of Concentrated Protein Solutions Oct. 2012 QENS & WINS 2012 at Nikko, Japan (10th International Conference on Quasielastic Neutron Scattering & 5th Workshop on Inelastic Neutron Spectrometer from Sep. 30 to Oct. 4, 2012) Probing reversible clusters in concentrated protein solutions Feb. 2012 Department of Nuclear Science & Engineering, MIT. (Invited by Prof. Sow-Hsin, Chen) Relation between cluster formation and intermediate-range order in colloidal systems Oct. 2011 Amgen Inc., Thousand Oaks, California, USA Cluster Formation in Concentrated Lysozyme Protein Solutions Jun. 2011 HANARO, Korea Atomic Energy Research Institute, Daejeon, Korea. (Invited by Prof. Sung-Min Choi) Applications of neutron scattering for soft-condensed matter and hydrogen storage materials Jun. 2011 Department of Engineering Physics, Tsinghua University, China. (Invited by Prof. Xuewu Wang) Neutron Scattering Studies of Soft-condensed Matter Materials at Modern Facilities Mar 2011 Department of Chemical Engineering, University of Delaware Studying structure and dynamics of concentrated colloidal solutions under equilibrium and non-equilibrium conditions using neutron scattering techniques Nov 2010 Institut Laue-Langevin, Grenoble, France Intermediate range order structure in lysozyme solutions Nov 2010 International workshop on dynamic crossover phenomena in water and other glass forming liquids, Fiesole, Florence, Italy Intermediate range order structure in lysozyme solutions Aug 2010 Colloquium talk at Department of Physics, Temple University Application of Neutron Scattering to Biological and Hydrogen Storage Materials Jun. 2009 Workshop on Compact Pulsed Hadron Sources (CPHS09), Tsinghua University, Beijing, China Structural characterization of nanoscale materials using small angle neutron scattering Feb. 2009 Department of Physics, The Chinese University of Hong Kong, Hong Kong, China Hydrogen adsorption properties in metal-organic frameworks Nov. 2008 The 2nd US-China Workshop on Scientific & Industrial Applications Using Neutron, Muons & Protons, 2008, Dongguan City, Guangdong Province, China Probing Hydrogen in Storage Materials Using Neutron Scattering Techniques Nov. 2008 Institute of Chemistry, Chinese Academy of Science, China. Applications of Neutron Scattering Techniques for Materials Science Research May 2008 American Conference on Neutron Scattering, 2008, Santa Fe, NM (For the tutorial session of SANS and Reflectometry for Soft Condensed Matter Research) Colloidal Interactions in Solutions Apr. 2008 Canadian Neutron Beam Centre, Ontario, Canada Hydrogen Storage in Metal-Organic Frameworks 16/18 Apr. 2008 Department of Physics & Astronomy, McMaster University, Canada Improving Hydrogen Storage in Metal-organic Frameworks Using Exposed Metal Sites Feb. 2008 Department of Materials Science and Engineering, Uni. Of Pennsylvania Improving Hydrogen Storage in Metal-organic Frameworks Using Exposed Metal Sites Dec. 2007 Materials Science Division, Argonne National Laboratory, Argonne, IL Storing H2 in Nano-porous Materials Nov. 2007 Material Research Society, 2007 Fall Meeting, Boston, MA Impact of Coordinatively Unsaturated Metal Sites of MOFs on H2 Affinity and Surface Packing Density Nov. 2007 ANS/ENS International Meeting and Nuclear Technology Expo, Washington D. C. Application of Neutron Scattering Techniques to Hydrogen Storage Materials Feb. 2007 SNS at Oak Ridge National Laboratory, Oak Ridge, TN Applications of Neutron Scattering to Biological and Hydrogen Storage Materials Nov. 2006 Department of Nuclear Science and Engineering, MIT, Boston, MA Characterization of Hydrogen Structure and Dynamics by Neutron Scattering Apr. 2005 Squishy Physics Seminar at Harvard University An effective long-range attraction between protein molecules in solutions studied by small angle neutron scattering. Contributed Talks: Mar. 2016 APS Annual March Meeting, Baltimore, MD Morphology of small sized clusters in a system with the competing interactions Jun. 2015 89th ACS Colloidal & Surface Science Symposium, Carnegie Mellon University, PA Effect of the cluster formation on the viscosity of concentrated monoclonal antibody solutions Jun. 2015 89th ACS Colloidal & Surface Science Symposium, Carnegie Mellon University, PA Short-time glassy-like dynamics observed in concentrated viscosity protein solutions with competing potential features Mar. 2015 Aug. 2014 APS March Meeting at San Antonio, Texas. Reversible cluster formation in concentrated monoclonal antibody solutions ECI Biological and Pharaceutical Complex Fluid, Durham, North Carolina Reversible cluster formation in protein solutions Mar. 2013 American Physical Society National March Meeting, 2013 at Baltimore, MD Session J34: Charged Colloids with Short-Range Attractions II Transition from monomeric state to dynamic cluster state in lysozyme protein solutions Oct. 2012 AICHE 2012 at Pittsburgh, PA Characterization of Monoclonal Antibody Conformations and Self-Associations at High Concentrations Using Neutron Scattering Techniques Jun. 2012 American Conference on Neutron Scattering Intermediate-Range Order in Charge Colloidal Systems with a Short-range Attraction Feb. 2012 American Physical Society National Meeting, Boston, MA Intermediate-range order in protein suspensions Jun. 2010 84th Colloid and Surface Science Symposium Dynamic Clusters in Lysozyme Protein Solution May 2010 Spallation Neutron Source, Oak Ridge National Laboratory Dynamic Clusters in Lysozyme Protein Solution Aug. 2009 238th ACS National Meeting and Exposition, Washington D. C. Equilibrium protein cluster in solutions: Dynamic or Static? 17/18 Jun. 2009 13th International Conference on Surface and Colloid Science and the 83rd ACS Colloid & Surface Science Symposium, New York, NY Study of the Short-Range Attraction of Globular Proteins in Solution May 2008 American Conference on Neutron Scattering, 2008, Santa Fe, NM Investigating Dihydrogen Binding to Coordinatively Unsaturated Metal Centers in Metal-organic Frameworks Mar. 2008 Materials Research Society, 2008 Spring Meeting, San Francisco, CA Reversible Structural Transition of MIL-53 and its Effect on Hydrogen Storage Dec. 2007 NIST Center for Neutron Research, Gaithersburg, MD Hydrogen Storage in Nano-porous Materials Nov. 2007 Material Research Society, 2007 Fall Meeting, Boston, MA Improving the Packing Density of Adsorbed Hydrogen and a Novel Configuration of Hydrogen Molecules in MOF-74 Mar. 2007 233rd American Chemical Society National Meeting, Chicago, IL SANS Studies of the Molecular Conformation and Structure of Charged G4 PAMAM Dendrimers in Aqueous Solutions Mar. 2007 American Physical Society March Meeting, Denver, CO Direct H2 binding to Unsaturated Metal Sites in Metal-organic Frameworks Mar. 2007 American Physical Society March Meeting, Denver, CO SANS Studies of the Molecular Conformation and Structure of Charged G4 PAMAM Dendrimers in Aqueous Solutions Nov. 2006 Material Research Society, 2006 Fall Meeting, Boston, MA Direct Observation of Hydrogen Binding to Unsaturated Metal Sites in Metal-organic Frameworks Apr. 2006 Material Research Society, 2006 Spring Meeting, San Francisco, CA Quantum Dynamics of H2 in MOF5 Studied by Inelastic Neutron Scattering Oct. 2005 Symposium on Bio-Materials and Neutron, AVS meeting, Boston, MA Effective Protein-Protein Interaction and Clustering Phenomenon in Solution Studied by SANS. 18/18