NIH 101: Applying for an R15 and R03

NIH 101: Applying for an R15
and R03
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Wednesday, November 18th, 2015
Office of Research and Sponsored Programs (ORSP)
www.wcupa.edu/research
SharePoint site:
https://sharepoint.wcupa.edu/vp/Advancement/SponRes
earch/default.aspx
Laura Vassallo ([email protected]) 610-430-5606
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The Role of ORSP
Very quick overview of NIH’s organizational structure
R15 and R03 Overview
Required Sections of a typical NIH proposal
How to create the budget
Working with the Program Manager
The approval process and how the PI and ORSP work together to
ensure a timely submission
• NIH Review Criteria and Policy
• Questions
• Presentation by Liz Grillo, Dept. of Communication Sciences and
Disorders
West Chester University Office of Research and Sponsored
Programs
Overview of Topics Covered
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• First and foremost, we are a customer service organization
• In very simple terms, our business is getting grants out the
door
• You are the customer
• Function differently than research offices at Research
Intensive Universities
• Assist in all stages of the proposal and budget development
process
• Facilitate Contact with Program Officer
• Review and Summarize Funding Announcement
• Submit application to the NIH
• Ensure an error-free submission
West Chester University Office of Research and Sponsored
Programs
The Role of ORSP
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National InstituteS of Health (IC’s)
http://www.nih.gov/icd/
Each Institute/Center (IC) has a different:
NIGMS
International Center
NIH’s mission is to seek fundamental knowledge about the nature and
behavior of living systems and the application of that knowledge to enhance
health, lengthen life, and reduce illness and disability.
West Chester University Office of
Research and Sponsored Programs
• mission & priorities
• budget
• funding strategy
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Type of Funding Opps
Description
Parent Announcements
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Requests for Applications
(RFAs)
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Uses Standard Receipt Dates (Feb, Oct, June)
By activity code (R01, R03, R15, R21 etc)
For “investigator initiated” or “unsolicited” research
ideas
Some ICs may not participate in all parent
announcements. (Check the funding
announcement)
Research must align with sponsoring IC mission and
goals
Solicit applications in a well-defined scientific
area to accomplish specific program objectives
Indicate the amount of set-aside funds and
anticipated number of awards
Often single receipt Dates
West Chester University Office of Research and Sponsored
Programs
Funding Announcements
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NIH Success Rates: http://report.nih.gov/success_rates/Success_ByIC.cfm
The AREA R15 Basics:
Program Announcement: PA-13-313
Key Features
• Project period is limited to 3 years.
• Direct costs are limited to $300,000 over the entire project period.
• Grants are renewable.
• Preliminary data are not required.
Funding Opportunity Purpose: to stimulate research in educational institutions, that
have not been major recipients of NIH support. AREA grants create opportunities for
scientists and institutions, otherwise unlikely to participate extensively in NIH research
programs, to contribute to the Nation's biomedical and behavioral research effort.
AREA grants are intended to support small-scale research projects proposed by faculty
members of eligible, domestic institutions.
Standard application deadlines
• February 25, June 25, and October 25
West Chester University Office of
Research and Sponsored Programs
Goals of the Program
• Support meritorious research
• Expose students to research
• Strengthen the research environment of the institution
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Participating
Organization(s)
Components of
Participating
Organizations
National Ins titutes of Health (NIH)
National Cancer Ins titute (NCI) National Eye Ins titute (NEI)
National Heart, Lung, and Blood Ins titute (NHLBI) National Hum an Genom e Res
National Ins titute on Alcohol Abus e and Alcoholis m (NIAAA) National Ins titute of Allergy
and Infectious Diseas es (NIAID)
National Ins titute of Arthritis and Mus culos keletal and Skin Dis eas es
(NIAMS)
National Ins titute of Biom edical Im aging and Bioengineering (NIBIB) Eunice Kennedy Shriver
National Ins titute of Child Health and Hum an Developm ent (NICHD)
National Ins titute on Deafnes s and Other Com m unication Dis orders (NIDCD)
National Ins titute of Dental and Craniofacial Res earch (NIDCR)
National Ins titute of Diabetes and Diges tive and Kidney Dis eas es (NIDDK)
National Ins titute on Drug Abus e (NIDA)
National Ins titute of Environm ental Health Sciences (NIEHS) National Ins titute of General
Medical Sciences (NIGMS) National Ins titute of Mental Health (NIMH)
National Ins titute of Neurological Dis orders and Stroke (NINDS) National Ins titute of Nurs ing
Res earch (NINR)
National Library of Medicine (NLM)
National Center for Com plem entary and Alternative Medicine (NCCAM) Divis ion of Program
Coordination, Planning and Strategic Initiatives , Office of Res earch Infras tructure Program s (ORIP)
National Institute on Minority Health and Health Disparities (NIMHD)
Funding Opportunity
Title
Activity Code
Announcement Type
Related Notices
Funding Opportunity
Announcement (FOA)
Number
Academic Research Enhancement Award
West Chester University Office of Research and Sponsored
Programs
earch Ins titute (NHGRI) National Ins titute on Aging (NIA)
(Parent R15)
R15 Academ ic Res earch Enhancement Award (AREA)
Reis s ue of PA-12-006
None
PA-13-313
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Vanessa Johnson and Susan Gans, Psychology Department*
• “Whole Family Biopsychology as a Marker for Adjustment”
• Funded August 2010; $215,400 over three years
• Eunice Kennedy Shriver National Institute of Child Health and Human
Development
Liz Grillo, Communication and Sciences Disorders*
• “Effectiveness of Telepractice by Smartphone App Technology in Preventing
Voice Problems”
• Funded September 2015; $410,260 over three years
• National Institute on Deafness and Other Communication Disorders
West Chester University Office of Research and Sponsored
Programs
WCU and the R15
Both of these funded grants were re-submissions of initially declined
proposals.
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*Full proposals are available at: ORSP’s R15 SharePoint Site
The R03 grant mechanism will support small research projects that can be
carried out in a short period of time with limited resources.
Application Characteristics
• You may request a project period of up to two years and a budget
for direct costs of up to two $25,000 modules or $50,000 per year.
• No preliminary data are required but may be included if available.
• The Research Strategy may not exceed 6 pages.
Scope
• Pilot or feasibility studies
• Secondary analysis of existing data
• Small, self-contained research projects
• Development of research methodology
• Development of new research technology
West Chester University Office of Research and Sponsored
Programs
NIH Small Grant Program (R03):
PA 13-304
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Organization(s)
Components of
Participating
Organizations
Funding Opportunity
Title
National Ins titutes of Health (NIH)
National Human Genome Research Institute (NHGRI)
National Institute on Aging (NIA)
National Institute on Alcohol Abuse and Alcoholism (NIAAA)
National Institute of Allergy and Infectious Diseases (NIAID)
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
Eunice Kennedy Shriver National Institute of Child Health and Human
Development (NICHD)
National Institute on Drug Abuse (NIDA)
National Institute of Environmental Health Sciences (NIEHS)
National Institute of Mental Health (NIMH)
National Institute of Neurological Disorders and Stroke (NINDS)
NIH Small Research Grant Program (Parent
R03)
Activity Code
R03 Small Grant Program
Announcement Type
Reissue of PA11262
Related Notices
Funding Opportunity
Announcement (FOA)
None
PA13-304
Number
Funding
Opportunity
Purpose
The National Institutes of Health (NIH) InvestigatorInitiated Small Research Grant
(R03) funding opportunity supports small research
projects that can be carried out in a short period of time with limited resources. The
R03 activity code supports different types of projects including pilot and feasibility
studies; secondary analysis of existing data; small, selfcontained research projects;
development of research methodology; and development of new research technology.
West Chester University Office of
Research and Sponsored Programs
Participating
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• Identify which institute is the best fit for your research:
• R03 contacts and research priorities of participating institutes
• R15 Research Priorities of Participating Institutes
• Contact ORSP
• http://wcupa.edu/research/contactInfo.aspx
• Notify Dean/Chair of your intent to apply for a grant
• Often just a simple e-mail informing your Dean/Chair of you
intention to apply, and the approximate timeframe.
• Contact Program Officer
• Every institute at the NIH that supports an RO3 and/or R15 has a
designated program officer for these mechanisms.
• Rely on your program officer for advice on grant applications and the
specific institute’s perspective on your research area.
• Contact ORSP if you need help identifying the correct PO for your
application.
• Helpful Article: Can we talk? Contacting grant program officers
West Chester University Office of
Research and Sponsored Programs
First Steps of proposal
development
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• Rule #1: Talk with your NIH Program Director before preparing your
application
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• Rule #100: Talk with your NIH Program Director before preparing
your application
*if you want to succeed…
From: NIH Grant Writing Workshop, John D. Porter, Ph.D.
Program Director
National Institute of Neurological Disorders and Stroke
National Institutes of Health
West Chester University Office of
Research and Sponsored Programs
Take Home: The 100 Cardinal Rules
for Writing an NIH Grant Application*
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Cover Letter (1 Page)
Project Narrative (1-3 sentences)
Project Summary (30 lines of text)
Specific Aims (1 page)
Research Strategy
• 12 pages for R15
• 6 pages for R03
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Additional Resources
Prepare Proposal page of ORSP
Web Site
Guidance for each required
Section of an NIH proposal
NIH Learning Community on
References Cited (no page limit)
ORSP SharePoint Site
Budget
Budget Justification (no limit)
Facilities and Other Resources (no limit)
Biographical Sketch (five pages)
West Chester University Office of Research and Sponsored
Programs
Required Sections of the NIH proposal
and page limits.
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What do you need to successfully complete the project? Below
are the most common budget needs, not everything may apply
to your project, and this list may not be exhaustive:
• Summer Salary
• how many months for how many years
• AWA
• How many for each semester/AY
• Undergraduate/Graduate Student Researchers
• how many hours, for how many weeks, summer/AY, rate
of pay (generally $10-$12/hr)
• Graduate Assistant
• Full time is 12 credits; 20 hours a week
• Travel (conferences or for research purposes)
• When, where, how long, and how many travelers
• Specialty Supplies/Equipment
West Chester University Office of Research and Sponsored
Programs
Information ORSP needs to
create the budget
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• Consultants/Contractors
• How many, rate of pay
• Subawards
• Institution, contact info for PI and Research Office
• Advisory Board
• Honorariums
• Human Subject Incentive Payments
• How many subjects, payment amount
Information for specific calculations can be found here:
http://wcupa.edu/research/documents/GrantBudgetWCUSpecificCal
culations.pdf
West Chester University Office of
Research and Sponsored Programs
Information ORSP needs to
create the budget (con’t)
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• At least 6-8 weeks prior to deadline, schedule an initial
meeting with your research representative. At this
meeting we will:
• Review the funding announcement in detail and discuss
all required sections of grant proposal
• Review roles and responsibilities of ORSP, PI, Chair and
Assoc. Dean
• Review timeline of submission and confirm deadline for
all required approvals.
• Review all compliance requirements (Human subjects,
Financial Conflict of Interest, Responsible Conduct of
Research, Technology Transfer etc.)
West Chester University Office of Research and Sponsored
Programs
Proposal Development and WCU Approval
Process
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Begin Proposal Development
ASAP
Notify Chair/Dean of intent to Apply
ASAP
Initiate Contact with Program Manager
ASAP
List of Budget items sent to Laura
1/21/2015
Rough Drafts sent to Laura for Review (if desired)
1/31/2015
Near final draft of specific aim, research strategy, budget,
budget justification along with internal cover sheet sent to
Chair/ Assoc. Dean for review, digital signatures and approval
of AWA
Request letters of commitment from Chair/Assoc Dean
indicating any support (ie AWA)
2/3/2015
Near final draft of specific aims and research strategy sent to
Laura for Review by Gautam Pillay, AVP ORSP
Final budget sent to restricted funds for approval
2/3/2015
Internal Cover Sheet signed by Chair/Dean sent to Laura
2/17/2015
ORSP will obtain signatures from the Provost and AVP of
Research
All final versions of application documents sent to this office
(individual sections can be e-mailed any time prior)
2/17/2015
ORSP representative will upload all documents to Assist
2/22/2015
PI reviews and approves final and complete application
package via Assist
Submission:
2/22/2015
Approval
Process starts
2/3/2015
2/3/2015
2/21/2015
2/24/2015
West Chester University Office of Research and Sponsored
Programs
Time line based on Grant due 2/25/2015, assuming first Contact with ORSP is
Early January
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NIH Review Criteria and Policy
4-5 months after submission
Application
DRR
Initial Peer
Review
(CSR or IC)
• Scientific focus &
mission relevance
• Scientific Review
Officers (SROs)
and Program
Officials (PO)
• Final Impact Score
6-7 months after
submission
National
Advisory
Council
For each application:
≥ Three qualified reviewers are assigned for in-depth assessment
Study sections make recommendations on:
Get inside information:
• Scientific and technical merit
Visit the NIH Reviewer
• Impact
Resources Website
̶ Impact scores
̶ Criterion scores
̶ Written critiques
• Other review considerations
• All Applications receive individual, numerical scores from
assigned reviewers (usually 3).
• The following categories are scored:
See Review Criteria
and Definitions
– Significance
- Approach
– Investigator(s)
- Environment
– Innovation
• Reviewers give numerical scores for each category
– 1 (exceptional) to 9 (poor)
1 – high
impact
9 – low
impact
West Chester University Office of Research and Sponsored
Programs
Scored Review Criteria
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West Chester University Office of Research and Sponsored
Programs
Score Descriptors
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• Voted on by all eligible SRG members, not just assigned
reviewers
• Calculated by averaging all reviewers’ votes and multiplying by
10. Range from 10 through 90
• Impact scores are available in about 3 days after the initial
peer review meeting
• Summary statement is viewable in eRA Commons within 30
days of initial peer review meeting.
• Contact your program officer after reading summary
statement (hopefully he/she knows you by now)
10 –
Highest
Impact
90 –
Lowest
Impact
West Chester University Office of Research and Sponsored
Programs
Final Impact Scores (assigned at initial peer
review for applications that are discussed)
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• All applications are peer-reviewed and scored before
study section meets.
• Streamlining allows discussion of more meritorious
applications.
• Requires full concurrence of the entire study section
• Summary statements contain:
• Reviewer critiques
• Criterion (individual reviewer) scores
• Applications designated as ND do not receive a final impact
score
West Chester University Office of
Research and Sponsored Programs
Streamlining Applications
(Not Discussed)
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Broad and diverse membership
Basic/research scientists
 Clinician scientists
 “Public” members
Recommend applications for funding
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Awards cannot be made without Council
approval
The Advisory Board/Council also considers the
IC’s goals and needs and advises the IC director.
The IC director makes final funding decisions
based on staff and Advisory Council/Board
advice.
West Chester University Office of Research and Sponsored
Programs
Final Step of Review: National
Advisory Council
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Liz Grillo, Ph.D., CCC-SLP
Associate Professor, Communication
Sciences and Disorders
West Chester University Office of
Research and Sponsored Programs
Thank You!
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West Chester University Office of
Research and Sponsored Programs