Columbia University Medical Center Know Your K Joan M. Lakoski, PhD • Robert J. Milner, PhD

ColumbiaUniversityMedicalCenter
KnowYourK
JoanM.Lakoski,PhD•RobertJ.Milner,PhD
NIHprovidesfundingforcareerdevelopmentat
differentstages
student
F31
F30
postdoc
resident
junior
faculty
Dividingupthe$30billionNIHpie...
senior
faculty
careerdevelopment
awards
F32
October30,2015
KAwards
Research
Projects
(53%)
Training
Career
Development
Awards
~$615million
(~2%)
R01
NIHCareerDevelopment(K)Awards
providesupportforresearchcareers
TheGoalofMentoredKAwards
~2%NIHbudget:$615million(FY15)
3,600awards(FY15)
Currently14differenttypes(K01-K99)
•  forclinicians&basicscien\sts
•  forjunior&seniorfaculty
MentoredKawards:
designedforpostdocs&juniorfaculty
—>K01,K08,K23,K99/R00
CandidatesareencouragedtoidenSfymorethan
onementor,i.e.,amentoringteam
Toprovidesupportand“protected>me”(3-5years)
foranintensive,supervisedcareerdevelopment
experienceinthebiomedical,behavioral,orclinical
sciencesleadingtoresearchindependence.
Adedicatedmentorisessen\alfor
•  successfulapplica\on
•  successfuloutcome
NIHprovidesfundingforcareerdevelopmentat
differentstages
postdoc
resident
PrimaryMentor
Mentee
Co-Mentor
Co-Mentor
Co-Mentor
Useyourmentoringteamtocomplementthe
exper7seofyouandyourprimarymentor
©2015RobertJ.Milner,Ph.D.&JoanM.Lakoski,Ph.D.
junior
faculty
independent
inves\gator
MentoredClinical
ScienSstAward
MentoredPaSent-
K23 OrientedResearch
MentoredResearch
K01
ScienSstAward
CareerTransiSon
K22
Award
Pathwayto
K99/R00
IndependenceAward
K08
1
K01:MentoredResearchScienRstAward
—todevelopresearchindependenceorto
fostercareerdevelopmentinanewarea
• forcandidateswithpoten[alfor
produc[veindependentresearch
• mentorwithextensiveresearch
experience
• 75%effortover3-5years
• differentIns[tutesusetheK01
awardfordifferentpurposes
—contacttheProgramOfficer!
K23:MentoredPaRent-OrientedResearchCareer
DevelopmentAward
—todevelopinves7gatorscommi:ed
topa7ent-orientedresearch
Requires:
•  clinicalornursingdoctoraldegree
•  comple[onofallclinicaltraining
•  mentorwithextensiveresearch
experience
•  75%effortover3-5years
K22:CareerTransiRonAward
—supportforpostdoctoralfellows
intransi7ontofacultyposi7ons
• forcandidateswithpoten[alfor
produc[veindependentresearch
• differencesamongIns[tutes:
mayinvolvetrainingin
intramuralNIHprograms
K08:MentoredClinicalScienRstAward
—todevelopclinicianresearchscien7sts asindependentinves7gators
Requires:
•  clinicaldoctoraldegree
•  musthaveini[ated
postgraduatetraining
•  mentorwithextensive
researchexperience
•  75%effortover3-5years
K99/R00:PathwaytoIndependenceAward
—tofacilitateindependentfunding
earlierinaninves7gator’scareer
• forhighlypromising
postdoctoralscien[sts
• establishedinresponseto
increasingageoffirst
independentsupport
• non-ci[zensareeligible
OtherindividualKAwards
K02 IndependentScien[stAward
K05 SeniorScien[stResearch&Mentorship
K07 AcademicCareerAward
K18 CareerDevelopmentAwardintheEnvironmental
HealthSciences/
CareerEnhancementAwardforStemCellResearch
K24 MidcareerInves[gatorAwardinPa[ent-Oriented
Research
K25 MentoredQuan[ta[veResearchDevelopment
Award
©2015RobertJ.Milner,Ph.D.&JoanM.Lakoski,Ph.D.
2
CommonfeaturesofKAwards
Kawardshavehighsuccessrates
SuccessRate2014(%)
Eligibility:
•  doctoraldegree
•  USCi[zen,non-ci[zenna[onal,or
permanentresident(exceptK99/R00)
•  noteligibleifpreviousPIonRorKgrants
#awards
2014
160
124
34
DuraRon:3–5years
178
Effort:minimum75%(butcanbe100%)
203
NewR01SuccessRate2014=15.4%
Datafrom:hlp://report.nih.gov/DisplayRePORT.aspx?rid=551
hlp://report.nih.gov/success_rates/Success_ByAc[vity.cfm
FormoreinformaRononKawards
seetheNIHwebsite—KKiosk
InformaRononKAwardsbyNIHInsRtute
NIHwebsite:
Kawardinforma[on
foreachawardforall
Ins[tutes/Centers
e.g.,K01Award
hlp://grants1.nih.gov/grants/guide/contacts/parent_K01.html
hlps://researchtraining.nih.gov/programs/career-development
ContacttheappropriateProgramOfficer!
KAwardsarereviewedby5criteria
Candidate
Careerdevelopmentplan
Researchstrategy
Mentor
Environment&
InsRtuRonalCommitment
Rememberthecriteria
asyouwriteyourproposal!
©2015RobertJ.Milner,Ph.D.&JoanM.Lakoski,Ph.D.
Downloadspreadsheet:
Kawardsuccessrates
forIns[tutes/Centers
hlp://report.nih.gov/DisplayRePORT.aspx?rid=551
ProgramAnnouncementsforKawards
(seeKKiosk*)
K01: MentoredResearchScien[stDevelopmentAward
PA-14-044
K08: MentoredClinicalScien[stResearchCareer
DevelopmentAward
PA-14-046
K22: seeindividualins1tutesonKKiosk*
K23: MentoredPa[ent-OrientedResearchCareer
DevelopmentAward
PA-14-049
*hlp://grants.nih.gov/training/careerdevelopmentawards.htm
3
ReadtheProgramAnnouncement(PA)
—linktoapplicaRonpackage&download
PA-14-036
PA-14-036
(K08award)
ApplicaRonforaKawardshouldbea
collaboraRonbetweenyou&youradvisor
You(the“applicant”)arePrincipalInvesRgator
•  youareresponsibleforsubmisng
theapplica[on
•  youwritetheresearchtrainingplanin
collabora[onwithyoursponsor
Youradvisor/mentoristheSponsor
•  she/hemustwritesec[onsoftheapplica[on
ApplyforGrantElectronically
Watchforupdates!
ThereareaddiRonalcomponents&instrucRonsfor
KAwards
CareerDevelopment
SupplementalForm:
InstrucRons:
PartI,Sec[on7
—prepara[onofa
Kawardproposal
Youmustinvolveyouradvisor/mentorearly&
oQenincraQingtheapplica7on!
CompletetheCoverComponentaccordingto
standardinstrucRons
Consultwithyour
grantsofficeforhelpin
comple[ngtheforms
YousigntheapplicaRonby
checking“Iagree”(Page2)
Title:limitedto81
characters&spaces
OtherProjectInformaRonForm
7.ProjectSummary/Abstract
• nomorethan30lines
• theabstractshouldinclude
adescrip[onofyourresearch
project&yourtrainingplan
9.Bibliography
•  forwholeproposal
Rememberthatinsubmisngtheapplica[on,you
cer[fythatthecontentsare“true,complete,and
accurate” ©2015RobertJ.Milner,Ph.D.&JoanM.Lakoski,Ph.D.
10.FaciliRes&OtherResources;11.Equipment
•  descrip[onofresourcesavailabletocandidate
•  establishesfeasibilityofproposal
4
Budget:allowablecostsmay
differbyawardtype&insRtute
• consultyour
grantsoffice&/or
ProgramOfficer
• modularbudgets
notusedfor
Kawards
• onlyafewbudget
categoriesused
TheapplicaRonalsoincludes
“PHS398Components”
CoverLekerComponent
•  requiredformentoredKawards
•  mustincludelistofreferences
CoverPageComponent
Checklist
•  followgeneralinstruc[ons
CareerDevelopmentSupplementalForm
Watchforchangesinforms!
“ApplicantsmustincludeaCoverLeker”
ThecoverlekermustincludealistofReferees
—listcompletecontactinforma[on.
Thecoverlelercanbeusedtorequestassignment
toaspecificIns[tuteand/orreviewpanel:
ApplicaRonTitle
Pleaseassignthisapplica[ontothefollowing:
Ins[tute/Center:
Na[onalIns[tuteofDrugAbuse(NIDA)
Scien[ficReviewGroup:
Fellowships:BehavioralNeuroscience(F02A-J)
ThecoverlePerwillbereplacedbyanewform
inapplica1onssubmiPedon/aRerMay25,2016
KeysecRonshaveapagelimit
Candidate
InformaRon
(items2–4)
+
ResearchStrategy
(item11)
TheCareerDevelopmentSupplementalForm
containstheproposalitself
ImportantsecRons:
• Introduc[on(ifapplicable)
• CandidateInforma[on
• StatementsofSupport
• Environmentand
Ins[tu[onalCommitment
• ResearchPlan
• HumanSubjects,etc
EachcomponentisaPachedasaseparatepdf
Watchforchangesinpagelimits!
RCR(item#5)nowhasaseparate1pagelimit
Plans&StatementsbyMentors&Co-mentors(item7)
—limitedto6pages
LekersofsupportfromConsultants&Collaborators
—limitedto6pages
InsRtuRonalenvironment(item9)limitedto1page
=12pagestotal
InsRtuRonallekerofsupport(item10)limitedto1page
+1pageforSpecificAims
Seecurrentpagelimits:
hlp://grants.nih.gov/grants/forms_page_limits.htm#car
©2015RobertJ.Milner,Ph.D.&JoanM.Lakoski,Ph.D.
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Tip:writetheCandidateInformaRon&Research
Strategyasasingledocument
ThesupplementalsecRonscorrespond
tothereviewcriteriaforKAwards
Belerabletoassessfitto12pagelimit
Candidate
Thenseparateintosec[onsforuploadingaspdfs
Careerdevelopmentplan
NIHwillnotcountwhitespacegeneratedaspartof
pagelimits
Researchstrategy
2.Candidate’sBackground
Candidate
InformaRon&
ResearchPlan
12pagestotal
Mentor
3.CareerGoals
Environment&
InsRtuRonalCommitment
4.CareerDevelopment
Rememberthecriteria
asyouwriteyourproposal!
11.ResearchStrategy
Candidate’sBackground(item2)
Describeanyrelevantinforma[onaboutyou
thatisnotincludedinyourBiosketch
•  e.g.,research,clinicaltrainingexperience
Besuccinct:
thissec[onisincludedinthe12-pagelimit!
Describeyour“ScienRficBiography”
inCareerGoals&ObjecRves(item3)
Jus[fytheproposalbydescribinghowitfits
intoyourcareerdevelopment
past
history
thisproposal
future
career
Describepreviousscien[fichistory
Describehowtheawardwillenableyouto
enhanceyourcareerobjec[ves
Includereasonsforanychangesincareerdirec[on
MentoredKAwardapplicaRonsrequire
lekersofreference
RequiredforK01,K08,K22,K23&K99/R00
applica[ons
• 3–5lelersfromindividualsotherthanthose
involvedintheapplica[on
• i.e.,notsponsor/mentororcollaborators
Lelersshouldaddresscandidate’scompetence&
poten[alasanindependentinves[gator
©2015RobertJ.Milner,Ph.D.&JoanM.Lakoski,Ph.D.
Listyourrefereesinthe
“OtherAkachments”secRon
Item#12inResearch&
OtherProjectInformaRon
ListofReferees:
•  atleast3,notincludingyoursponsor
•  youmustincludethenameofthereferee,
departmentalaffilia[on,andins[tu[on
•  samelistmustbeincludedinthe
CoverLe:erComponent
6
Describewhatyouwilllearnin
theCareerDevelopmentPlan(item4)
Describenewskills&knowledge
•  providedetailsofcourses&workshops
Definedistribu[onofeffortforac[vi[es
(use[meline)
Relateac[vi[estocareerdevelopment&research
plans
Proposingtodowhatyoualreadyknowwill
beviewedashavingnotrainingpoten7al!
Yourmentor(s)mustdescribe
detailedplansformentoring
Thespecificexper[seofyourmentorsandhowtheir
guidancewillhelpyoutoachieveyourgoals
Thespecificsofmentoring,includingfrequencyof
mee[ngs(e.g.,weekly)
ConsideraddinganAdvisoryCommileetomonitor
yourprogressevery6months
ResearchPlanshould“developskills
neededbyaresearcher”
Itemsthatyoumustincludein
aCareerDevelopmentPlan
Describeyourgoals:
•  whatyouhopetoachieve...
•  describespecificac[vi[esdesignedtoachieve
eachgoal
•  includeaspecificaspectofadvancedresearch
trainingandprofessionalskills
(e.g.trainingingrantwri[ng)
•  describehowyourins[tu[onalenvironmentwill
enhanceyoursuccessinachievingyourgoals
IncludeaTimelinefor
yourCareerGoals&ObjecRves
List:
•  yourdistribu[on
ofeffort
•  specific
objec[vesforeach
year
•  plansfor
subsequentgrant
support
TheMentormusthaveastrongrecordof
researchandmentoring
• shouldbehypothesis-driven
• notoverlyambi[ousorrou[ne
Yourmentorshouldmeetthesequalifica[ons
(&documentthemadequately!)
FormatoftheResearchPlan:
SpecificAims(1page)
ResearchStrategy:
a)  Significance
b)  Innova[on
c)  Approach
Ifnot,provideaplantocorrectanydeficiencies:
• co-mentor(s)
• mentoringadvisoryteam
©2015RobertJ.Milner,Ph.D.&JoanM.Lakoski,Ph.D.
7
StatementsbyMentormustalsoexplain
howawardwilldevelopcandidate’scareer
Shouldinclude:
•  plansforcandidate’scareerdevelopment
•  source(s)ofsupportforresearchproject
•  supervision&mentoringofcandidate
•  candidate’steachingload(ifany)
•  planfortransi[onofcandidatetoanindependent
inves[gator
Statementlimitedto6pages!
AstrongstatementofInsRtuRonal
CommitmentisessenRal(item9)
• onins[tu[onallelerhead
• commitmenttocandidate
independentofaward
• agreementtoprovideprotected
[meforcandidate’sresearch&
careerdevelopment
• equipment,labspace,office,
facili[es,resources
Le:erlimitedto1page!
©2015RobertJ.Milner,Ph.D.&JoanM.Lakoski,Ph.D.
InsRtuRonalEnvironment:documenta
strongresearchprogram(item8)
Listnamesofkeyfacultymembers
Describeavailabilityofnecessaryfacili[esand
resources(refertoresourcesdescrip[on)
Describeopportuni[esforintellectualinterac[ons
(journalclubs,seminars,presenta[ons)
Statementlimitedto1page!
Writetothereviewcriteria!
Candidate
Careerdevelopmentplan
Researchstrategy
Mentor
Environment&
InsRtuRonalCommitment
Astrongresponseforeachcriterion!
8