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honors biology ch. 5 Notes Membranes
honors biology ch. 5 Notes Membranes MEMBRANE STRUCTURE AND FUNCTION 5.1 Fluid Mosaic model of the plasma membrane “Fluid” The molecules can migrate through the layer that they are in but they will very seldom flip-flop. “Mosaic” The pattern or collection of molecules (phospholipids and proteins) that makes up the plasma membrane. 5.1 Describe the diverse functions of membrane proteins 50 different types of proteins found in RBC’s. Six Functions: 1. Support: (see graphic) a. integrins give the membrane a stronger framework. b. Span the membrane and attach to the cytoskeleton on the inside and the extracellular matrix (ECM) on the outside 2. cell-cell recognition: (see graphic) a. glycoproteins (sugar-protein) b. glycolipids (sugar-phospholipid) c. “glyco” or sugar acts as ID tags i. embryo sorts cells into tissues and organs ii. immune system to recognize and reject foreign cells like bacteria 3. intercellular junctions: 4. enzymes (see below) 5. signal transduction (see below) 6. transport (see below) 5.1 Relate the structure of phospholipid molecules to the structure and properties of cell membranes. Selective Permeability: Membranes allow some substances to cross more easily than others. Molecules that can move across plasma membrane are soluble in lipid (phospholipid tails are hydrophobic-“like dissolves like.”) Molecules that Move across easily Molecules that need proteins to get Small, nonpolar molecules across membrane Small polar (water) Larger, nonpolar charged Mrs. Loyd [email protected] Page 1 of 1 http://loydbiology.weebly.com 10/20/11 http://www.mybiology.com 5.2 Explain how the properties of phospholipids spontaneously form membranes. • One of the first organic molecules to form on early Earth • Spontaneously self-assemble into simple membrane “bubbles” • without help from DNA • “membrane-bound sacs” surrounding beneficial chemistry (protobiont) was important stepping stone to first cell. • Hydrophilic heads “love” water inside and outside cell • Hydrophobic tails “fear” water and huddle together • “Like dissolves like” 5.3 Define diffusion and describe the process of passive transport. Diffusion: Particles spread out evenly in an available space, from high concentration to low due to thermal motion (heat). NEVER requires energy. Passive Transport: The diffusion of a molecule across a membrane from high to low concentration or down its concentration gradient. Small, nonpolar molecules like O2 and CO2 diffuse easily. Small, polar water diffuses easily. Large, polar molecules and ions can diffuse across using a transport protein (facilitated diffusion). Passive Active H→L L→H No energy Uses Energy Examples: Diffusion endocytosis • osmosis exocytosis Facilitated Na+/K+ pump Diffusion-Glucose 5.4 Explain how osmosis can be defined as the diffusion of water across a membrane. • Osmosis is a special case of diffusion, it is specifically for water. • It is defined as water moving across a membrane from H→L concentration. • Predicting how water will move across a membrane will be your main challenge in this chapter. 5.5 Distinguish between hypertonic, hypotonic, and isotonic solutions. Hyper = “over” like “hyperactive” Hypo = “under” like “hypodermic needle” Iso = “same” like “isosceles triangle” Tonic = solute These terms are relative. We will always be comparing one side of a membrane to the other side. (outside a cell vs. inside the cell.) Mrs. Loyd [email protected] STEPS in determining the direction of osmosis Latin Solute English Solute English Water Place your L, then H→L Decide if water is entering or leaving the cell (Draw a PICTURE!) Determine the results Determine what will happen Page 2 of 2 http://loydbiology.weebly.com hypertonic “over” salty “under” watery H→L use next figure 10/20/11 http://www.mybiology.com 5.5 Explain how animal and plants cells change when placed into hypertonic or hypotonic solutions. Complete your “Osmosis Worksheet” to practice. 5.6 - 5.8 Compare the processes of facilitated diffusion and active transport. Facilitated Diffusion: • uses a protein embedded in the membrane to facilitate, or help, a substance diffuse across the membrane. • Example: Glucose has its own protein in the cell membrane for this purpose. • It is diffusion, so the sugar moves from H→L concentration of sugar. Active Transport: • USES ENERGY • L→H Moves molecules against their concentration gradient. • Examples: o endocytosis o exocytosis o Na+/K+ pump 5.9 Distinguish between exocytosis, endocytosis, phagocytosis, pinocytosis, and receptor-mediated endocytosis. Use animations Mrs. Loyd [email protected] Page 3 of 3 http://loydbiology.weebly.com 10/20/11 http://www.mybiology.com