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vermont medicine U N I V E R S I T Y O F V E R M O N T C O L L E G E O F M E D I C I N E using educational technology W I N T E R / S P R I N G 2007 vermont medicine U V M C O L L E G E O F W I N T E R M E D I C I N E / FROM THE DEAN 2 COLLEGE NEWS 3 S P R I N G 12 PRESIDENT ’ S CORNER CLASS NOTES DEVELOPMENT NEWS OBITUARIES 2 0 0 7 FALLING DOWN THE RABBIT HOLE A professor ponders what it is to be in gravity’s grip on his journey through life with ALS. Campaign tops goal, students don their coats, new chairs in medicine and surgery, and more. HALL A M A G A Z I N E by joseph patlak, ph.d. 29 30 31 33 38 16 PINPOINTING THE SCIENCE BEHIND AN ANCIENT HEALING ART Medical researcher Helene Langevin, M.D., conducts a rigorous, meticulous investigation of acupuncture. by stacey chase 22 EDUCATIONAL TECHNOLOGY The College of Medicine is at the forefront of using 21st Century tools to teach today’s innovative curriculum. photo essay by raj chawla and edward neuert on the cover: photograph of Adetola Fadeyibi, class of 2010, viewing a COMET pathology slide by Raj Chawla RAJ CHAWLA vermont medicine FROM THE DEAN W I N T E R / COLLEGE NEWS S P R I N G 2 0 0 7 Though I have attended many White Coat ceremonies here at the College of Medicine, none have been more special to me than this February’s event in Ira Allen Chapel. As Interim Dean I welcomed students from the Class of 2010, and their friends and family from all over the world, many of whom had spent many long hours traveling to Vermont through the record-breaking blizzard that had ended only hours earlier. Vermont itself had donned a white coat of sorts, and the sun shone brilliantly as we made our way to the chapel through chest-high piles of snow. We heard speaker Allan Ramsay, M.D., remind the students that, important though the white coat is as a symbol of commitment, it is the commitment within the person wearing the coat that is most important to focus on. That commitment is evident throughout the stories and updates you will find in this issue of Vermont Medicine. In January many friends and longtime colleagues of Professor Joe Patlak, Ph.D., joined Joe and his family to celebrate his quarter-century commitment to the College. Joe, who was diagnosed with amyotrophic lateral sclerosis several years ago, continues to educate us with his elegant essays that he presents on his blog: one such dispatch is reprinted here. Helene Langevin, M.D., has staked out a unique and very interesting commitment: to illuminate, through rigorous scientific investigation, the mechanisms behind the ancient art of acupuncture. Finding the basis behind such “complementary” medicine is increasingly important, as patients more and more add such components to their own treatment regimens. My background reminds me that we use ceremonies and programs as traditions to reflect on our values and what is important as future professionals. The students who received their white coats — indeed, all students at the College — find that medical education is filled with such traditions. At the same time, we are exposing them to a revolutionary, innovative, ever-improving curriculum. Delivering that curriculum in the most effective and accessible way is what our largely in-house developed educational tools are all about. The photo-essay in this issue shows you some of the technological tools that help students absorb the increasing amount of material that makes up medical education today. Finally, none of our efforts here would get very far without the financial support shown by the alumni, staff, parents, and friends of the College. The fact that the university and the school have both reached or exceeded their goals for the current fundraising campaign is a milestone that deserves our recognition, and our heartfelt thanks. 2 V E R M O N T M E D I C I N E RAJ CHAWLA UVM Exceeds $250m Campaign Goal EDITOR edward neuert ASSISTANT DEAN FOR COMMUNICATIONS & PLANNING carole whitaker WRITER jennifer nachbur ART DIRECTOR elise whittemore-hill UNIVERSITY OF VERMONT COLLEGE OF MEDICINE INTERIM DEAN john p. fogarty, m.d. EDITORIAL ADVISORS rick blount ASSISTANT DEAN FOR DEVELOPMENT & ALUMNI RELATIONS marilyn j. cipolla, ph.d.’ 97 ASSOCIATE PROFESSOR OF NEUROLOGY christopher s. francklyn, ph.d. PROFESSOR OF BIOCHEMISTRY james c. hebert, m.d.’ 77 ASSOCIATE DEAN FOR GRADUATE MEDICAL EDUCATION With several months remaining in the official timeline for its comprehensive fundraising campaign, the University of Vermont has exceeded the $250 million campaign goal. President Daniel Mark Fogel announced that total commitments to the Campaign for the University of Vermont went over the top at $250.6 million as of the end of the day January 18, 2007. Launched in July of 2001 as only the second campaign in UVM history, the Campaign for the University of Vermont is concentrated on raising funds primarily for student scholarships, faculty support, and facilities. “This signal achievement is a tremendous vote of confidence in UVM and an affirmation of an intense, widely-shared belief in the University’s value and quality,” Fogel said. “We should also see this moment as freighted with the obligation to meet the high expectations UVM has been working toward and as a call to continue to develop the philanthropic resources that will be key to fulfilling the promise, not least of all by intensifying our efforts to increase the campaign total through to its deadline in June of this year.” Fogel expressed gratitude for “the generosity of our wonderful donors and volunteers and for the coordinated efforts of deans, faculty, staff, and our colleagues in Development and Alumni Relations.” He gave THE CAMPAIGN FOR THE UNIVERSITY OF VERMONT • $250 million fundraising goal • Launched in 2001, public phase of campaign was announced in fall 2003 • College of Medicine initial $60 million goal increased to $80 million in 2005 • College of Medicine fundraising now exceeds $83 million special thanks to the members of the university’s Board of Trustees and to the National Campaign Steering Committee. “Their support and that of the entire university community has positioned the University of Vermont to realize its overarching goal in the years ahead—to become known as the nation’s premier small public research university,” Fogel said. Two years ago, the College of Medicine’s original campaign goal of $60 million was informally increased to $80 million, due to the enthusiastic initial response from donors. Campaign giving to the College now stands in excess of $83 million. russell tracy, ph.d. SENIOR ASSOCIATE DEAN FOR RESEARCH & ACADEMIC AFFAIRS A COAT, AND A COMMITMENT vermont medicine is published three times a year by the University of Vermont College of Medicine. Articles may be reprinted with permission of the editor. Please send address changes, alumni class notes, letters to the editor, and other correspondence to University of Vermont College of Medicine Alumni Office, Given Building, 89 Beaumont Ave., Burlington, VT 05405. telephone: (802) 656-4014 Letters specifically to the editor may be e-mailed to: [email protected] UVM’s Ira Allen Chapel was filled with students, faculty, staff, and family members on Friday, February 16, who braved the post-blizzard snowy conditions for the annual White Coat Ceremony. Begun in the 1990s to mark the beginning of clinical education for medical students, the ceremony is a public commitment by students to compassionate patient care and scientific proficiency. This year’s address at the ceremony was given by Professor of Family Medicine and Associate Professor of Medicine Allan Ramsay, M.D. UVM MEDICAL PHOTOGRAPHY W I N T E R / S P R I N G 2007 3 & COLLEGE NEWS AWARDS Biomedical Research Center Launched with New Grant An $11.4 million grant will allow UVM to conduct five new studies on Centers for Disease Control-designated “priority pathogens” — infectious agents that impact the health of millions of people worldwide. The funding will launch the Vermont Center for Immunology and Infectious Diseases — a nationally competitive Center of Biomedical Research Excellence (COBRE) in the rapidly growing field of immunology and infectious diseases. This award marks the third COBRE grant UVM has received from the National Center for Research Resources at the National Institutes of Health since 2000. Directed by Ralph Budd, M.D., professor of medicine and director of UVM’s immunobiology program, the COBRE grant builds on the university’s well-established expertise in immune response to infection and medically significant infectious agents such as bacteria, viruses and parasites. The COBRE program fosters collaborations between senior faculty mentors and five promising junior faculty, provides training for graduate students and will support an additional three new faculty in the areas of immunology, infectious diseases, and microbial pathogenesis respectively. An interdisciplinary group of faculty from six departments and three colleges at UVM will participate in the COBRE. The grant also supports technology expansion in two of UVM’s core laboratory facilities — proteomics and microarray. Gary Ward, Ph.D., associate professor of Ralph Budd, M.D., professor of medicine and director of UVM’s new grant for its Center of Biomedical Research Excellence in immunology/infectious diseases. microbiology and molecular genetics, is co-director of the grant. “This is a unique opportunity to foster a program of science in a culture of mentoring,” said Budd. “It draws upon the highly collaborative spirit of UVM’s talented faculty to develop a truly interdisciplinary study of the immune response to infectious agents. The Center will not only provide a nurturing atmosphere for students and faculty, it will benefit the health of Vermonters, as well as provide an economic engine for skilled jobs.” UVM’s two other COBRE grants have both received continuation grants in the past year and a half. The Center for Neuroscience Excellence program recently received a continuation grant of $11.1 million and the Translational Research in Lung Biology and Disease program has received continuation grant funding totaling $11.1 million since 2005. New AHEC Medical and Research Directors Paula Duncan, M.D. Charles MacLean, M.D. Interim Dean John P. Fogarty, M.D. has announced two appointments in the Office of Primary Care and the Area Health Education Centers Program (AHEC). Paula Duncan, M.D., professor of pediatrics, has been named medical director, effective; and Charles MacLean, M.D., associate professor of medicine, has been named research director. Both report to Fogarty in his role as associate dean for primary care, and will work closely with Elizabeth Cote, director of the AHEC Program. “We are pleased to have these two outstanding faculty members, who possess such strong commitments to the health of Vermonters, providing leadership for primary care and AHEC,” said Fogarty. “The Office of Primary Care and AHEC will play an increasingly important role in the College of Medicine and across Vermont, in keeping with the state’s growing need for a stronger health care workforce, solid networks of community faculty to provide health care for Vermonters, strengthened research and education programs and expanded efforts in chronic care.” Duncan will maintain her faculty appointment and continue her work in the department of pediatrics and as youth health director for the Vermont Child Health Improvement Program and co-director of the Generations course in the curriculum. MacLean, who joined UVM/Fletcher Allen Health Care as assistant professor of medicine in 1988, will maintain his faculty appointment and continue his activities and research within the Primary Care Internal Medicine division. THIS PAGE : RAJ CHAWLA , UVM MEDICAL PHOTOGRAPHY ; TOP RIGHT: EDWARD NEUERT; BOTTOM RIGHT, VMS RECOGNITION Lewis First, M.D., professor and chair of pediatrics and senior associate dean of medical education at the College, received the 2006 national Education Award at the American Academy of Pediatrics (AAP) National Conference and Exhibition on October in Atlanta, Georgia. The Education Award is presented annually to recognize a member of the AAP whose educational contributions have had a broad and positive impact on the health and well being of children and adolescents. The College of Medicine Class of 2009 celebrated their completion of the Foundations Level of the Vermont Integrated Curriculum (VIC) on February 2, and presented the following awards: Outstanding Foundations Course — Cardiovascular, Respiratory and Renal Systems; Foundations Course Director Award and the Dean Warshaw Integration Award (for the faculty member whose teaching best captured the spirit of the VIC) — William Hopkins, M.D.; Foundations Teaching Award — John Lunde, M.D.; The Silver Stethoscope (for the faculty member who had few lecture hours, but made a substantial contribution) — James Hudziak, M.D.; Above and Beyond Award — Masatoshi Kida, M.D.; Best Support Staff (Non-teaching) — Mary Campbell; AMSA Golden Apple Award — Robert Macauley, M.D.; Outstanding Teaching Assistant Award — Derek Strong. Robert Klein receiving his scholarship award from Mimi Reardon, M.D. ’67 John Murray, M.D.’63, a local pediatrician and College of Medicine clinical professor of pediatrics, and Robert Klein, a third-year medical student, were among several individuals honored at the Vermont Medical Society’s 2006 Annual Meeting. Murray, who practices at Timberlane Pediatrics in South Burlington and Burlington, was recognized for providing 38 years of exceptional health care to children in Chittenden County with the 2006 Distinguished Service Award — the highest honor that the society can bestow on one of its members. Medical student Robert Klein received a $10,000 Mildred A. Reardon, M.D. Scholarship from the Vermont Medical Society Education and Research Foundation (VMSERF). Named in honor of Mildred Reardon, M.D.’67, a professor emerita of medicine at the College of Medicine who was instrumental in forming the VMSERF, the scholarship is given annually to a medical student who is committed to practicing medicine in Vermont after completing residency training. Also at the annual meeting, the VMS named David L. Johnson, M.D., associate professor of anesthesiology, as the society’s new president for 2006 – 2007. Interim Dean John P. Fogarty, M.D., announced in January that Brian Cote has been appointed associate dean for finance and administration at the College. Cote has served as the assistant dean since 2004, and has taken on an increasingly significant role in managing the strategic financial and human resources of the College. Cote will also continue in his role as treasurer of University Medical Education Associates (UMEA) and will join Information Systems Interim Director Russell Tracy, Ph.D., and UVM Chief Information Officer David Todd in helping to develop strategic direction for the College’s IS operations. SCHWEITZER FELLOWS ’ BOOK DRIVE HELPS FAMILIES IN TREATMENT Lystra Hayden (above) is one of seven second-year medical students at the College of Medicine who received a 2006-07 Schweitzer Fellowship to conduct a community service project. Hayden, whose fellowship project focuses on opiate-addicted mothers, spearheaded a book drive to create a lending library for clients at The Chittenden Center, the local treatment clinic for opiate dependence. The fellows sorted, cleaned, labeled and then presented more than 1000 donated books. In addition to Hayden, the current class of Schweitzer fellows at the UVM College of Medicine includes Gaurab Basu, Sarah Grimm, Dung Huynh, Gilda Ngo, Ginny Van Duyne and Russ Meyer. W I N T E R / S P R I N G 2007 5 COLLEGE NEWS RESEARCH MILESTONES NOT READY TO QUIT SMOKING ? TRY CUTTING BACK PARSONS NAMED MEDICINE CHAIR AND CLINICAL LEADER Interim Dean John P. Fogarty, M.D., of the College of Medicine, and Melinda Estes, M.D., President and CEO of Fletcher Allen Health Care, have announced the appointment of Polly Parsons, M.D., as E.L. Amidon Professor and Chair of Medicine at the College of Medicine and Physician Leader of Medicine at Fletcher Allen Health Care. Parsons was previously Interim Chair and Physician Leader of Medicine since June of 2005. She has served as Director of Pulmonary and Critical Care Medicine and Chief of Critical Care Services at UVM and Fletcher Allen since 2000. In addition, Parsons has held multiple national leadership positions, including serving on and chairing National Institutes of Health (NIH) grant review committees and chairing the FDA Advisory Committee on Pulmonary-Allergy Drugs. “Dr. Parsons is an outstanding investigator and scholar with extensive leadership experience in pulmonary and critical care medicine and expertise as a clinician and teacher,” said Fogarty. “She is internationally recognized in the field of Acute Lung Polly Parsons, M.D. Injury/Acute Respiratory Distress Syndrome and pulmonary disease research, and has been the recipient of several grants from the National Heart, Blood and Lung Institute of the National Institutes of Health (NIH).” “Polly has provided strong leadership as Interim Chair and Physician Leader of Medicine since June of 2005 and has a solid platform of success on which to build moving forward,” said Estes. “She has made significant contributions as a past president of the Fletcher Allen Medical Staff, and in service on key internal boards and committees.” Parsons is a past president of the Fletcher Allen Medical Staff and served on the Faculty Practice Board and the Strategic Management Committee. Named one of America’s Top Doctors for four consecutive years (2001–04) and again in 2006, she was honored with the 2006 Elizabeth A. Rich, M.D., Award from the American Thoracic Society. UVM and Fletcher Allen Name Taheri Clinical Affairs Leader Paul Taheri, M.D. 6 Interim Dean John P. Fogarty, M.D., and Fletcher Allen President and CEO Melinda Estes, M.D., have announced the appointment of Paul Taheri, M.D., M.B.A., as president of the Faculty Practice at Fletcher Allen and senior associate dean for clinical affairs at the College of Medicine. Taheri, a native of Buffalo, N.Y., was selected following a national search. He was most recently director of trauma surgery at the University of Michigan Health System, as well as vice chair of surgery for hospital affairs and associ- V E R M O N T M E D I C I N E ate dean for academic business development at the University of Michigan School of Medicine. A practicing general/trauma surgeon with a Master’s degree in business administration from the University of Michigan School of Business, Taheri leads a group of more than 480 physicians at UVM/Fletcher Allen and joins Fletcher Allen’s senior management team. In his role as senior associate dean for clinical affairs, he will oversee the Office of Clinical Trials Research and Graduate Medical Education. In addition, Taheri will continue to practice medicine, working as a general surgeon in the Department of Surgery, specializing in trauma, burns and critical care. Taheri earned a Bachelor of Science degree from St. Lawrence University and graduated from New York University School of Medicine. Taheri’s professional and academic activities include membership in the American College of Surgeons, American Burn Association, American Association for the Surgery of Trauma and the Eastern Association for Trauma, and the publication of more than 60 papers in national and international journals. He has participated in numerous health care special projects at the University of Michigan over the last decade, including projects focused on optimizing operating room scheduling and enhancing Emergency Department throughout. JOHN HUGHES : UVM MEDICAL PHOTOGRAPHY ; ALL OTHERS : RAJ CHAWLA In a review article in the December Nicotine and Tobacco Research, researchers at the University of Vermont have found an unexpected, effective alternative to motivate smokers to quit smoking – cutting back. According to the qualitative review of 19 studies on smoking reduction in individuals who did not want to quit, this method, typically coupled with the use of nicotine replacement products, led to an increase in quitting in 16 of the studies. “Cutting back is approved as a method of quitting in several European countries, but not in the United States,” said lead author John Hughes, M.D., a professor of psychiatry at the College of Medicine. “Our review contradicts the commonly held belief that quitting requires stopping abruptly and provides evidence that smokers can quit successfully by reducing the amount of cigarettes smoked. Furthermore, our review indicates cutting back is often a great way to start changing smoking that can lead to eventual quitting.” Hughes and colleague Matthew Carpenter warn that smokers do need to understand that there is no good evidence that cutting back alone decreases smokingrelated health risks and thus clinicians should promote reduction only as a step towards eventual cessation to their patients. WHAT ’ S GOOD FOR THE HEART IS GOOD FOR THE VEINS New research shows that diet can influence a person’s risk for vascular disease. In a study published in January in Circulation: Journal of the American Heart Association, researchers including Mary Cushman, M.D., associate professor of medicine, discovered that middle-aged adults who ate a diet rich in fish, fruits and vegetables lowered their risk of developing a potentially fatal blood John clot by more than 40 percent. Lead study author Hughes, Lyn Steffen, Ph.D., of the University of M.D. Minnesota School of Public Health, Cushman, and colleagues tested the hypothesis that foods rich in B vitamins and w-3 fatty acids can lower venous thromboembolism (VTE) incidence and meat intake can promote incidence of VTE. The dietary pattern associated with lower risk of VTE in this study is similar to that suggested for reduced cardiovascular disease by the American Heart Association 2006 Diet Recommendations, suggesting that such a diet may reduce the risk of VTE. POTENTIAL KEY TO BRAIN BLOOD - FLOW DISORDERS College of Medicine scientists have clarified the cellular process responsible for signaling regional blood flow changes in the brain, thereby uncovering possible causes for such disorders as stroke, migraine, and Alzheimer’s disease. The study was published in November in the prestigious journal Nature Neuroscience.The mechanisms by which neurons in the brain signal blood vessels to dilate and increasing blood flow to different regions remain largely unknown, and are central to understanding brain function. The diameter of blood vessels in the brain can be modulated by extracellular potassium, a common element present inside and outside all cells of the body. Such modulation of vessel diameter permits changes in blood flow to occur in the brain, as well as in other organs and tissues. With this knowledge, lead study author Mark Nelson, Ph.D., professor and chair of pharmacology, set out to determine whether the diameter of cerebral blood vessels in the brain could be modulated under physiological conditions by external potassium ions. To accomplish this, he and his research team studied the communication that takes place between neurons and blood vessels in mouse and rat brains. The research team discovered early on that neuronal activity appeared to be communicated to the blood vessels through intermediary cells known as astrocytes. Astrocytes, which comprise about half the brain, had not been previously thought to play an active role in brain processes. In addition to Nelson, the research team included Jessica Filosa, Ph.D., postdoctoral fellow in pharmacology; Adrian Bonev, Ph.D., research assistant professor of pharmacology; Stephen Straub, Ph.D., postdoctoral fellow in pharmacology; Keith Wilkerson, Ph.D., postdoctoral felAdrian Bonev, Ph.D., low in pharmacology; and collaborators Stephen Straub, at Stanford University. Ph.D., and Mark Nelson, Ph.D., in the Totman Lab. W I N T E R / S P R I N G 2007 7 COLLEGE NEWS McFadden Named Chair and Clinical Leader of Surgery David McFadden, M.D. has been named Stanley S. Fieber Professor and Chair of Surgery at the College of Medicine and Physician Leader of Surgery at Fletcher Allen Health Care. McFadden was most recently professor and chair of surgery, surgeon-in-chief and chief of general surgery at West Virginia University. A general surgeon specializing in surgical oncology, he was also a member of West Virginia’s Mary Babb Randolph Cancer Center. He earned a medical degree from the University of Virginia and completed a surgical internship and residency at The Johns Hopkins Hospital, followed by a year as assistant chief of service and instructor in surgery at Johns Hopkins. In 1987, he joined the faculty at the University of Cincinnati Medical Center and then in 1992 moved to the University of California Los Angeles, where he was named director of the General Surgery Residency Program and chief of the Division of General Surgery. In 2000, McFadden joined West Virginia University. He also held the position of interim chair of orthopaedics there from 2002-03. McFadden, who has performed funded research in the areas of gastroenterology, endocrinology, oncology and pancreatic physiology for two decades, holds a 1996 patent for a method of inhibiting the growth of pancreatic tumors. He is the author of more than 210 articles in leading medical journals and has delivered nearly 100 national and international invited presenta- MEDICAL ADMISSIONS: NEW LEADERSHIP, NEW PROCESSES “This is first and foremost a team effort,” says Janice Gallant, M.D.’89, who this past fall was appointed the College’s new associate dean for admissions. Sitting in her office on the second floor of the Given Building, with Director of Admissions Tiffany Delaney at her side, Gallant emphasizes the collaborative nature of the job of crafting each successive class of new medical students. “It’s the work of the Admissions Committee — all that voluntary effort — that really makes a successful process,” she says. “We have an experienced, knowledgeable, caring, hard working and committed group of people whose primary goal is the selection of an excellent class of medical students who will go on and become excellent physicians/scientists serving the community and the world through important clinical, educational and research endeavors,” says Gallant. “Someone who applied to medical school as recently as five years ago might not recognize the process now,” explains Tiffany Delaney. “Today’s medical school application process is virtually paper-free, with applicants receiving much of their information through online sources. At the College of Medicine, applicants are able to follow the progress of their application through a secure website that tells then of their status throughout the process.” The goal is to create a seamless and informative application experience for applicants. “We try to provide information on all aspects of the medical school experience — from financial aid and financial planning, to the curriculum and student life,” says Delaney. “Applicants who interview at the College of Medicine spend the day learning about the College of Medicine — from its history to current events (include COMET, the VIC, and student life). Even current students are involved by sharing lunch with applicants and leading tours. Applicants are also met and greeted by a senior associate dean or the dean of the College himself.” “I think the College of Medicine is seen by applicants as a very challenging and very enjoyable place to learn,” says Gallant, who speaks with each group of interviewing applicants during the admission season and asks them specifically what made them apply to UVM. “The reasons students want to enter medicine do not seem to have changed over the years — despite the immense changes we have seen in technology. Our applicants speak of caring, compassion and of an intense desire and drive to help others.” Chair of Surgery David McFadden, M.D. tions on his work. Co-editor in chief of the Journal of Surgical Research since 1997, McFadden has been an active member of the Association for Academic Surgery since 1987, serving as its president and on the Board of Directors. Named one of America’s Top Doctors four times, he is the recipient of two Outstanding Attending Awards at West Virginia, as well as the Dean’s Award for Clinical Excellence. He has mentored medical students, residents and fellows, and earned the UCLA Golden Scalpel Award for Excellence in Teaching three consecutive years. McFadden replaces Steven Shackford, M.D., who stepped down as chair of surgery last May after 17 years of leadership. Shackford continues to serve as professor of surgery and is a practicing vascular surgeon at Fletcher Allen. STUDENTS DISPLAY VERMONT PUBLIC HEALTH PROJECTS 8 V E R M O N T M E D I C I N E TOP : RAJ CHAWLA ; LEFT: ANDY DUBACK , BOTH UVM MEDICAL PHOTOGRAPHY ADMISSIONS BY THE NUMBERS 6160 applications for the Class of 2011 10% increase in applications in the past year 110 Top Honors TOP : RAJ CHAWLA ; RIGHT: COURTESY BRITTON KEESHAN More than 100 second-year University of Vermont medical students showcased 14 recently-completed public health projects at a special reception focused on Vermont’s most critical health issues on January 24 in the Health Science Research Facility Gallery. Joining the students for the event were Interim Dean John P. Fogarty, M.D., Jan Carney, M.D., associate dean for public health, and representatives from the United Way of Chittenden County and Vermont social service and nonprofit agencies. The College of Medicine’s Public Health Projects program is designed to teach students to approach health issues affecting populations of people in the broadest and most practical sense. Among the Public Health Projects conducted during the fall of 2006 were programs focused on preventing suicide in Vermont teens, improving asthma education, promoting physical activity in children, and communicating environmental health risks. Associate Dean for Admissions, Janice Gallant, M.D. ’89, and Director of Admissions Tiffany Delaney. Expected number of Class of 2010 positions All the 110 members of the class of 2010 came to the college this fall with their own individual stories of hard work along the journey to medical school. Britton Keeshan is undoubtedly the first-year student with the highest altitude on his trek. The Connecticut native was the youngest person ever to summit the highest peak on each of the world’s continents, beginning with Denali in 1999 and ending with Everest in 2004, when he was 22. He is pictured here on Everest, holding photos of his famous grandfather, the late Bob “Captain Kangaroo” Keeshan, whom he credits with encouraging him to “push the boundaries and seek the outer limits of whatever I was doing.” 41% Vermont residents in class of 2010 W I N T E R / S P R I N G 2007 9 COLLEGE NEWS Q U E S T I O N S O N H E A R T FA I LU R E Ophthalmologist, Orthopaedic Researcher are New Named Professor Posts with Martin LeWinter, m.d. Martin LeWinter, M.D. VERMONT MEDICINE: What causes heart failure and what are its consequences, in terms of related health conditions, as well as from the perspective of economic burden? MARTIN LEWINTER: Almost any disease process that can affect the heart can cause heart failure — heart valve disease, various types of congenital heart defects, alcoholism and viral infections are examples. However, the most important causes are coronary artery disease with associated damage to the muscular wall of the heart, hypertension and type 2 diabetes mellitus. Typically, these three major factors occur in various combinations. There is also a fairly large group of patients with what is termed idiopathic dilated cardiomyopathy, meaning heart muscle disease without a known cause. Interestingly, recent evidence indicates that a significant proportion of these “idiopathic” cases are caused by mutations. The symptoms of heart failure are mainly shortness of breath and peripheral fluid build-up. The severity of symptoms is extremely variable, ranging from minimal disability to patients who are bedridden. While the great majority of patients have at least some disability, modern treatment has had a major positive impact. Survival with heart failure 20 years ago was dismal, but there has been significant and progressive improvement. It is still a very serious problem, but there is real reason for hope in the majority of patients. The economic burden of heart failure is enormous. It is the single most common diagnosis in Medicare patients and 10 V E R M O N T M E D I C I N E Recent statistics from the American Heart Association show that after age 65, roughly 10 out of every 1,000 people per year suffer from heart failure, the ineffective pumping of the heart that leads to an accumulation of fluid in the lungs. As director of the heart failure program in the division of cardiology, Martin LeWinter, M.D. professor of medicine and molecular physiology and biophysics, examines heart failure as a clinician and a basic scientist. Among his many multi-year research studies are two projects designed to identify the molecular mechanisms responsible for a condition that causes heart failure called diabetic cardiomyopathy. LeWinter is the principal investigator of a new, $1.25-million, five-year grant from the National Heart, Lung and Blood Institute, which will establish a regional consortium for conducting heart failure research in northern New England. Brian Kim, M.D., assistant professor of surgery, and Bruce Beynnon, Ph.D.’91, professor of orthopaedics and rehabilitation, have each been named to succeed Brian Kim, Ph.D. to a named faculty endowment in their respective departments at the College of Medicine. Kim is the next Duncan Persons, M.D.’34 Green & Gold Professor in Ophthalmology. Beynnon is the McClure Professor in Musculoskeletal Research. Kim earned a medical degree from St. Louis University and joined the faculty in 2006. His research specialties include age-related macular degeneration, diabetic retinopathy and macular edema. the costs are currently on the order of tens of billions of dollars per year. NIH-funded research in heart failure, particularly in the areas of primary diseases of the heart muscle and responses of the heart muscle to chronic stress. The department of molecular physiology and biophysics, the cardiology unit in the department of medicine, and the cardiothoracic surgery unit have collaborated on this effort. One of the most novel and unique aspects of UVM’s heart failure research has involved the use of extremely small biopsies obtained by our cardiothoracic surgery colleagues during cardiac surgery. Our biopsy techniques have allowed us to perform fundamental studies in patients during various phases of heart muscle disease and failure and to capture a more realistic understanding of basic mechanisms and treatment options. Roughly 300 such biopsies have been performed over the last 15-plus years. What prompted the National Institutes of Health to set up regional research consortiums focused on heart failure? Advances in basic science and technology have resulted in an explosion of potential new approaches to the management and treatment of heart failure and a need for efficient mechanisms to bring these approaches quickly from the laboratory to the bedside. The concept is to put together a group of diverse centers with expertise in heart failure that can accomplish clinical trials quickly and flexibly, with sufficient numbers of patients, and with great expertise. The studies envisioned for this network and the RCCs consist of novel management strategies that are not usually undertaken by the pharmaceutical industry and clinical trials of new therapies that require relatively small studies to test their efficacy in advance of larger, more definitive industry-funded trials. Some of these approaches might not be carried out by industry because of limited financial returns. A second major goal is to quickly disseminate the knowledge gained to practicing physicians, as well as industry. What is UVM’s history in this area of research? What information has your previous work in heart failure uncovered that will aid you in this regional effort? UVM has a long history of both basic and translational RAJ CHAWLA Beynnon earned his undergraduate, masters, and doctoral degrees from UVM and has been a member of the faculty since 1986. He is a member of several orthopaedic journal editorial boards. His research has earned him many awards, including the O’Donoghue Sports Injury Research Award of the American Orthopaedic Society for Sports Medicine. The Persons Professor is named in memory of Dr. Duncan Persons, an ophthalmologist who graduated from the College of Medicine in 1934 and left an estate gift to fund the endowment. The McClure Professorship was established in 1988 by a generous gift from Lois H. McClure and the late J. Warren “Mac” McClure. known as PPAR-δ agonists that are used in the treatment of diabetes. Our hypothesis is that these drugs have unique properties (compared to other drugs used to treat diabetes) that will improve the effects of diabetes on the heart muscle. Many diabetes patients have heart muscle abnormalities that can be detected using a ultrasound testing (echocardiography), so we will use this technology to determine if improvement occurs over time with drug treatment. If our hypothesis is correct, this would constitute the first treatment shown to reverse the effects of diabetes on the heart muscle. The projected number of subjects for this trial is around 500. The other project will exploit our myocardial biopsy methods in patients with diabetes as well as hypertension, which typically occur together. This trial will require 160 to 170 patients willing to undergo biopsy during heart surgery. We understand that there are two research projects planned. What is the focus of these projects and how many study participants do you expect to enroll? At the end of the grant’s five years, what do you and your colleagues hope to have discovered? We submitted two proposed projects in applying for this grant, both of which are centered on diabetes and the heart. In the future, we will have opportunities to propose additional trials. One of the projects is a one-year, placebo-controlled, randomized trial of a class of insulin-sensitizing drugs Diabetes has a number of deleterious effects on the heart that account for the fact that it is an extremely potent risk factor for heart failure. At the end of the five years, we hope to have made a real contribution to the prevention and treatment of diabetes-related heart failure. LEFT: RAJ CHAWLA ; RIGHT: SABIN GRATZ Bruce Beynnon, Ph.D.’91 W I N T E R / S P R I N G 2007 11 Suddenly, I was falling. Time changed, perceptions heightened, For the last few years, Professor of Molecular Physiology & Biophysics and Pharmacology Joe Patlak has dealt with amyotrophic lateral sclerosis as a “part of my journey through the garden of life,” as he describes it on his internet blog. This essay is just one of the elegant dispatches from that sojourn to be found at http://viewpoint-als.blogspot.com. g fdown allin the rabbit hole by joseph patlak, ph.d. 12 PHOTOGRAPH BY ELKE PINN , M . D.’89 the world became a different place. My precipice was nothing more than the slightly uneven threshold at the front door of our local truck rental place. That little extra unanticipated step caused my knee to buckle, and my ALS-weakened legs had no reserve to compensate. Time slows in that moment between standing and landing. I was looking for a handhold, wondering who might be seeing me in my moment of embarrassment, trying at least to fall with grace. I was falling, and in a split second I was journeying out of the world of the able. This is the fall of ALS. Amyotrophic Lateral Sclerosis is a disease of the motor neurons. Although the nervous system has trillions of working cells called neurons, most are fairly small and only responsible for local communication. One type of nerve cell is the motor neuron. They are huge by comparison, like oldgrowth sequoias, stretching from brain to spinal cord, or from cord out to the muscles themselves. In most people the motor neurons function without interruption throughout life, giving us the ability, usually taken for granted, to deliberately control our movements. ALS affects specifically these mega-neurons, for reasons that are not understood. It often strikes in the prime of life, and when it does, it burns through these old-growth stands with the ferocity of a forest fire. First only minor changes are noticeable, but within the next few years weakness and paralysis spread progressively from one region to the next. My own case is fairly typical: at age 52 I noticed that my left hand and arm were weakening, and that my legs felt odd, shaky. Working with my neurologist, we ruled out other diseases that could have caused such changes. But nothing fit the symptoms like ALS. In the end it doesn’t matter what name or neurological classification one uses: I am losing motor neurons at a precipitous rate, and there is no known way to do a thing about it. A diagnosis like this stereotypically comes with a warning to “get your affairs in order”. Suddenly the balance of normal life was gone, the footholds vanished. I have been falling for two years. At first the changes were so minor, yet the knowledge of future weighed so heavily. The famed sequence of denial, anger, bargaining, depression, and acceptance came all at once, jumbled, changing daily, hourly. But acceptance came quickly enough. There I was, like an old fashioned cartoon character, hanging midair, several steps beyond the precipice but only slowly realizing how far down the bottom looked. I was falling. 13 As a society we love to fall. Some jump from planes for the exhilaration of a few minutes free fall, others seek out the highest peaks to ride down, or the highest cliffs to dive from. It’s the ride that counts, the control on the descent, the grace of the final landing. At that moment, hanging still at the top of the precipice, I suddenly had to decide how I would fall, how I might stay in control of the ride, how I might land. 4 Adaptation is the only defense when ALS is on the rampage. As one muscle failed, I learned to adapt by substituting a different one. If my dominant left hand could no longer write, my right hand wrote instead. If my leg couldn’t move, my arm did the work. It’s remarkably automatic, although there is always an adjustment period. I had to start adapting my expectations, my relationships, my emotions as well. Not least, my home would have to adapt. My wife Elke and I live in Vermont because, 25 years ago, I was offered a great job here. We live in rural Vermont because we feel best out in this countryside, where life melds into the quiet rhythms of nature. Our house echoed the long traditions of buildings in this valley—two storey, with an additional room carved under the eaves of the attic; steep stairs that were closed off by doors; small rooms, porches and a myriad of floor-level changes —and we loved it. Falling as I was, though, we had to view the house through different lenses. For a wheelchair, our beloved house would be a trap. We had a year, perhaps a bit more, before the rising tide of my disability would drive us from our home. We chose, instead, to adapt our housing like I was trying to adapt my body. We worked with an architect experienced in handicapped design, and with a dedicated contractor. We eliminated my need to climb stairs by building a new bedroom and bathroom in an addition. We opened up the interior to make as many 5’ turning circles (for wheelchair turns) as we could get, and we put in a neat covered ramp leading up to the mudroom. We juggled finances, we found a temporary condo, and we packed everything we didn’t immediately need into the basement and upstairs. Finally, we moved out, in the middle of a March blizzard. In the process, we needed a truck rental, and my job was to pick up the truck first thing in the morning. That’s when I fell. 14 V E R M O N T M E D I C I N E There were no hand-holds inside that truckrental doorway, at least not in the direction of my fall, just a corrugated layer cake of shifting cardboard. My leg bent cleanly and naturally under me, and all too quickly I was splayed out in an uninjured jumble of arms and legs. The store was deserted that early, so I was granted the luxury of time to sort out the worst of the jumble and sit up before anyone happened along. The guy on morning shift came by a minute later, to find me leaning on his cardboard mountain, eyeing the displayed stack of tow-bars for its potential as a climbing gym. “Can I help you?” he asked. “I’m feeling just fine, but my leg is weak and it gave way. I was just about to get myself up.” “Great, give a holler if you need help.” It was a quick, anonymous interaction, a few words before he went on with his work, before I pulled myself up the tow-bars. I imagined calls to 911, EMTs rushing in, hours spent waiting for an overworked Emergency Department resident to check on my status. But my fears evaporated. All it took was a quick separation of two important concepts, wellness and ability. It took but a few words to say I was well, a look from eye to eye, a light tone of voice. Well meant not ill, and not ill meant not medical. By being well, I was upright, oriented, descending, but still in control. Not able—no big deal—we all reach a level where help is necessary— give a holler. I was discovering that I could stay in control, even while falling. 4 Like Alice in her rabbit hole, I found the well very deep and the fall very slow. I had time to grab at marmalade jars, to probe into cupboards at each level. Falling slowly, but not able to stop or even pause a while. Yet I don’t fall alone. One Thursday evening last spring, Elke and I went to the local repertory theater. We were slowed by my awkward gait, by my cane, and we arrived at the last minute, once most seats were already filled. We edged our way between the set and the front row of the theater-in-the-round audience, almost on stage ourselves. My foot hit something unexpected in this tight, uneven terrain, and despite Elke’s firm grip on one side, and a cane on the other, I had my usual encounter with the floor. But gracefully—onto a knee first, then a thigh, keeping my head and shoulders up, more like an enforced sit — no pain, no sprain. Help was offered in overabundance, and Elke and I used a convenient stage chair to get me sitting, then standing, and finally into my designated seat. Again, the wellness was apparent, and my inability was ostensibly taken for granted. The play started, and my brief embarrassment was quickly forgotten in the joy of the production. Yet I was not alone that evening, as I found out at intermission. Thursdays was the night for the local retirement community’s outing to the theater, and much of the audience was over 80. I was warmed by an outpouring of octogenarian empathy, for these were folks who knew falling, who feared it for its life-threatening potential, who knew what it meant to gradually fail in your abilities. My fall took me through the community of the elderly, and they hospitably treated me as an honored guest. Before leaving I learned the grace of my elders who have come to terms with life as it is and with an impending end. I have moved on, always drifting downward. Construction was completed, we reinvaded our house, and I’ve moved into position for the next acts of the drama. My legs are nearly useless, one arm is limp, and stomach, back and neck are getting unsupportably weak. A wheelchair is my vehicle of choice these days (indeed, I may be turning into a connoisseur of wheeled personal vehicles). I am passing through the community of the disabled. This seems a more solitary place, as I journey in the caring arms of loved ones, largely separate from those who reside here. I didn’t grow up here, and I won’t be staying for long, so I go as a stranger. Yet the residents have made their mark. Sidewalks and public buildings have ramps, doors are workable, provisions made and ADA regulations addressed. Although our world is far from perfect for the wheelchair-bound, I thrill, in my naïveté, at each success. Without support from the shoulders of the giants who have shaped this landscape, I would have long-since crashed. ALS is a prism, spreading out the spectrum of disability, showing one hue at a time, a continuum of abilities spread out over time. At each point in that spectrum, one can be well or one can be ill, because that is a separate, unconnected gradient. Those who reside in the community of the disabled know this, and now I know it too. Regardless of On January 11, 2007, friends and colleagues gathered in the HSRF Gallery to celebrate the more than quarter-century career of Joe Patlak. Joe is internationally recognized for his expertise in single molecule biophysics, focusing on ion channels and molecular motors in the cardiovascular system. As an educator, Joe was founding course director of the Cardiovascular, Respiratory, and Renal course within the Vermont Integrated Curriculum and Director of an NIH Training Program in Molecular Mechanisms of Muscle Contraction. One of Joe’s most notable impacts on the College of Medicine was his introduction of the Internet to the College years before it became a commonplace of everyday life. ability, one can be well and ready to continue the journey. But as my abilities fail, the bottom of the well, the rabbit hole, looms. I may crash land, I may continue to plumb new depths, or I may crumple gracefully into a jumble of arms and legs. Will the ride become too tedious, too painful, too exotic to maintain? Could I really decide to pull out, this close to the end? All I can do for now is fall—perhaps to the bottom, still graceful, unable to fall any more. VM W I N T E R / S P R I N G 2007 15 pin pointing the science behind an ancient healing art by STACEY CHASE L ying on a beige table in the stark orthopaedics lab at the University of Vermont College of Medicine in Burlington, participant after participant endures the insertion of hair-thin needles mid-thigh and just below the knee, while five researchers, led by Research Associate Professor of Neurology and Orthopaedics Helene Langevin, M.D., monitor a body of machinery: ultrasound scanner, torque sensor, electrocardiograph, and laptop, on which the volunteers rate the needling sensations on a scale of 0 to 10. Langevin, glasses halfway down her nose, hovers between the device that is measuring torque and the study volunteer — in this instance, Sue Burns, an administrator in the university’s biochemistry department who suffers from arthritis and is facing hip-replacement surgery. Burns became a study subject because she’s interested in acupuncture and the possibility that it might relieve her pain. photograph by SABIN GRATZ 16 “She’s one of the highest-funded “We’re trying to relate what’s Research Associate acupuncture researchers in the coungoing on locally with your percep- Professor Helene try,” says Ted Kaptchuk, an assistant tions and your cardiovascular func- Langevin, M.D., in her professor of medicine at Harvard Given Lab. At left, tion,” Langevin tells her. Medical School and an authority on This on-going study, which is the special needleChinese medicine. “In the acupuncture largely aimed at investigating the implantation device. field, she’s a celebrity.” torque, or twisting force used in Though she rarely wears the white needle rotation, is the latest in Langevin’s dogged, single-minded quest to pinpoint lab coat, Langevin has a scientist’s love of the reguthe scientific basis behind the Chinese healing art larity of lab work, meticulous research skills, and that has been practiced for millennia but whose standards as rigorous as her intellect. “I’m more interested in investigating it,” she says of acupuncphysiology has never been fully understood. Demystifying acupuncture could eventually ture, “than practicing it.” mean better diagnosis and treatment of ailments like chronic pain and usher acupuncture into this eated at a gray steel desk in her austere, country’s medical mainstream. Only an estimated 4 percent of U.S. adults have tried acupuncture. cramped office on the fourth floor of the “Unless we understand the mechanism of these Given Building, and dwarfed by the piles of treatments,” Langevin says, “it’s going to be very medical tomes and esoteric articles and hard for them to get integrated into our health care abstracts, Langevin analyzes data and crosssystem, including insurance reimbursements.” sectional ultrasound images of needles Langevin’s innovative research into the ancient inserted into the tissue of live human subjects and therapy has gained nationwide, even worldwide, rodent models. She muses: “It’s really like solving a attention. Langevin — a third-generation physician big puzzle, you know?” who is both a board-certified internist (with a subAs far back as 300 B.C., Chinese texts described specialty in endocrinology) and licensed acupunc- acupuncture treatments and a reaction to the turist — presented her findings at scientific meet- needling called de qi (pronounced day chee), ings in China and Hong Kong this past December. thought to be important in achieving its therapeutic Two months earlier, she won a grant worth an effect. During de qi, two phenomena occur: one senexpected $1.9 million from the National Institutes sory, one biomechanical. The patient usually expeof Health’s National Center for Complementary riences a slight ache in the area surrounding the and Alternative Medicine, bringing her grant-fund- needle, while the acupuncturist may feel the needle ing total over the past seven years to more than $4.4 being grasped by the tissue — a tug often described million. Only a few faculty members at the College as akin to a fish biting on a line. Langevin made headlines in 2001 when the peerof Medicine have ever received NCCAM funding. S 18 V E R M O N T M E D I C I N E JORDAN SILVERMAN reviewed Journal of Applied Physiology published the results of a landmark study in which she and her colleagues quantified de qi’s biomechanical component, or needle grasp, by measuring the force necessary to pull an acupuncture needle out of the skin. Her research showed something else: Gently manipulating the needles back and forth or twisting them clockwise significantly increased the pullout force — which sometimes reached 500 grams, or slightly more than a pound — over no rotation at all. The increase was 52 percent with back-andforth movement, and 167 percent with clockwise turning. Moreover, the force needed to retract a needle, with or without rotation, was on average 18 percent greater at traditional acupuncture sites than at control points. “The important thing is that needle manipulation increases needle grasp, and we found this everywhere — but slightly more at acupuncture points,” Langevin says. A key to Langevin’s receiving her first grant was a custom-made, hand-held needling device resembling a dentist’s drill that records all the measurable parameters on an attached computer; an earlier proposal in which acupuncture needles were inserted and retracted by hand was rejected because investigator bias could not be eliminated. Four years ago, Langevin and partners David L. Churchill, Ph.D., an engineer at MicroStrain Inc. in Williston, and Burlington acupuncturists Robert Davis and Bonnie Povolny, founded Stromatec Inc., a Burlington company now developing prototype torque sensors — a miniaturized version of the needling device — for possible use in teaching acupuncture techniques, research, and clinical practice. The venture was underwritten by a National Institutes of Health grant that encourages investigators who are also inventors to take their inventions into the marketplace. UVM holds the patents on both the instrument and method of measuring needle torque. As she continues to unravel acupuncture’s ancient mysteries, Langevin’s research has proved that the connective tissue that winds around acupuncture needles — much like spaghetti wadded around a fork — is responsible for needle grasp. The commonly held notion had been that a muscle contraction was the likely cause. Further study has revealed that needle manipulation transmits a signal to fibroblasts, the cells that make up such tissue, causing them to spread and flatten. “The needle is, in fact, stretching the tissue from the inside,” Langevin explains. “The tissue is not just being pulled, it’s actively responding to the stimulus. The connective tissue is dynamically responsive to the mechanical stimulation. This is completely new.” The fibroblasts’ response to the needling initially stunned researchers, who had believed the cells might ball up. But flawed predictions and sheer surprises are part of the joy of scientific discovery for this physician-turned-physiologist. “If you’re right, that’s great,” Langevin says. “But if you’re wrong, then it sometimes gives you even more information because, a lot of times, it’s what’s unexpected that’s beyond what you could even imagine.” It’s that kind of indefatigable ego, coupled with the high quality of Langevin’s research, that has earned her the respect of fellow physicians, acupuncturists, and researchers. “She’s trained as an acupuncturist, but she’s not a proponent,” Kaptchuk says. “One of the things that’s really remarkable about her work is it’s the only acupuncture research that’s absolutely replicable. She measures every thrust, every force.” U sing needling and ultrasound imaging, Langevin and her team are now beginning to test her newest hypothesis: that connective tissue abnormalities occur more frequently in patients with low back pain than others. “So far, we don’t know that there’s anything wrong with the connective tissue in people with low back pain,” she says. “But if we determine the winding is abnormal, this would be a hint that the connective tissue may cause or perpetuate this pain.” Such a discovery could eventually lead to better treatment options for sufferers, including not only acupuncture but also manual-based therapies like massage. Langevin’s attempt to elucidate the mechanism of acupuncture by looking at cellular changes in the poorly studied connective tissue is novel. “There are Western scientists who think it’s all about nerve stimulation,” says Peter Wayne, Ph.D., former research director of the New England School of Acupuncture in Watertown, Mass., and the new director of Tai Chi research programs at Harvard W I N T E R / S P R I N G 2007 19 University of Traditional Chinese Medicine and the Chinese University of Hong Kong — in the birthplace of acupuncture — were particularly unusual for a foreigner. “I did not know what kind of reception I was going to get,” Langevin admits, “but they were very cued into what I was talking about. They were enthusiastic about the research.” B “One of the things that’s really remarkable about her work is it’s the only acupuncture research that’s absolutely replicable. ” Medical School, “but she’s opened up a whole new model. She’s very interested in the fundamental biology of this [connective] tissue… which will offer broad insights into all of medicine, not just acupuncture.” Langevin also hopes to demonstrate a pattern of abnormality in the needling response of patients that corresponds to specific meridians, or the twelve main energy channels that acupuncturists believe run through the body, as predicted by traditional acupuncture theory. Since publishing her ground-breaking study on de qi in 2001, Langevin’s research has evolved from investigating the mechanism of acupuncture to examining basic connective tissue physiology. The hoped-for next step would be clinical trials on low back pain patients in an effort to prove acupuncture’s efficacy. “Imagine that you could show that a course of acupuncture treatment would result in changes in the needle response,” Langevin says. “Then it won’t be difficult to go to the doctors and say, ‘This is how it works.’ Because then we’ve shown that not only do people feel better — because that could be a placebo effect — but the tissues have changed. So, to me, that would be very, very powerful.” Robert Hamill, M.D., a neurologist and chair of the Department of Neurology at the College of Medicine, marvels that Langevin’s rise to promi- 20 V E R M O N T M E D I C I N E nence in the world of acupuncture took just five short years. “Every now and then someone is in the right place at the right time and makes a sentient observation that revolutionizes a field,” he says. “She’s a crisp thinker. …She’s made it a scientific discipline when so much of it was smoke and mirrors.” Hamill recalls that when Langevin first came to the university ten years ago, she was merely looking for “a corner of a lab bench.” Today, she runs her own lab, staffed with an assistant, research engineer, and two technicians. “From this very meager beginning, she very quickly captivated a lot of folks. She has a remarkable ability to look across disciplines and bring technology and approaches from other fields to the questions she is asking,” he says, noting Langevin’s collaboration with the departments of physics, radiology, pathology, and medical biostatistics, among others. An unlikely West-meets-East trailblazer, Langevin has presented her research at scientific gatherings in Barcelona and Munich, among a number of foreign cities, in the past two years. But recent lectures to researchers at the Shanghai JORDAN SILVERMAN ack home in Vermont, the French-Canadian professor walks or bikes to campus from the nearby home she shares with her husband and two children. “I do go home to my kids each night. And I do relax,” says Langevin. But in the lab, she is known for her formidable focus on the task at hand. “She’s like a laser beam,” says Jim Fox, the research engineer in her lab. Hers is an intellectual curiosity born of personal experience. During her residency at Johns Hopkins Hospital in 1985, Langevin sought acupuncture for nerve-injury pain after exhausting all that Western medicine had to offer. After three months of treatments on her leg, her pain was gone. “I was intrigued by this strange way of looking at the anatomy in terms of the meridians,” she says. “The fact that I got better was almost irrelevant in my decision to study it.” But Langevin’s relentless fascination with acupuncture has only raised more questions — and more hypotheses — and she tosses them rapid-fire into the air as if to make room for new ones already forming in her mind. “What are meridians? What are the needles doing? What kind of effect does it have on the tissue? How does it help the body heal?” she ponders. “If we understood all that, I think doctors would feel much more comfortable recommending acupuncture.” Until then, Langevin will continue the hunt for answers. “I love this work,” she says. “I truly love it.” And it isn’t hard to image her 20 years from now, holed up in her office, the itch to understand the science behind acupuncture still under her skin. “Helene has single-handedly rescued acupuncture research from the dead end it had reached because of [previous] findings that had been inconclusive or contradictory,” Kaptchuk says. “I don’t know if Helene is going to solve the acupuncture riddle, but she has the best chance of anybody.” VM DAVE BARRINGTON C O M P L E M E N T A R Y Gingko Biloba M E D E C I N E The growing role of complementary medicine was recognized nine years ago with the formation of the National Center for Complementary and Alternative Medicine (NCCAM), the nation’s lead agency for the study of traditional healing in the context of rigorous science. Researchers at the College of Medicine are studying the healing properties of the leaves of the Ginkgo biloba tree, one of the oldest tree species in the world, which have been used for thousands of years in traditional Chinese medicine to treat diseases of the heart and lungs, and to “benefit the brain.” Today, scientists at UVM’s Laboratory for Clinical Biochemistry Research, led by Senior Associate Dean for Research and Academic Affairs Russel Tracy, Ph.D., participate in the Ginkgo Evaluation of Memory Study (GEM), an NCCAM-funded study that seeks to find out if medicine made from the ginkgo leaf can delay dementia, the common changes in memory, thinking and personality that can occur with age. GEM may help to determine if Gingko biloba can help to slow or prevent the progression of Alzheimer’s disease. In other ginkgo-related research, Professor of Anatomy & Neurobiology and Neurology Felix Eckenstein, Ph. D., and colleagues have published on the prevention of age-related spatial memory deficits in transgenic mouse model of Alzheimer’s disease by Ginkgo biloba treatment. On the educational front, the Consortium of Academic Health Centers for Integrative Medicine recently accepted the UVM College of Medicine as one of four new member schools: Yale, Stanford, the University of Colorado were the others admitted. This prestigious opportunity allows the College to join with 35 other academic centers to further understanding and knowledge in integrative health. W I N T E R / S P R I N G 2007 21 one morning in mid-August of 2003, one of those invisible boundaries between the way things used to be and the way they are now was quietly but firmly crossed at the College of Medicine. That day, the Class of 2007 entered, and became the first class of students to begin their full medical education under the College’s new Vermont Integrated Curriculum (VIC). That same day, those students each received their school-issued laptop — their first portal to COMET, a new set of electronic learning tools developed at the College that would become an increasingly important part of their learning environment. Developed by faculty, staff, and students over the course of several years, COMET is now an integral part of each student’s day. “We had many interesting pieces of educational technology, like the CATSlab pathology tools, here at the College before the VIC introduction,” says Jill Jemison, who leads the COMET development team. “But what COMET did was deliver a learning management system that offered universal access — to every student, every faculty member, to every lecture and piece of course content. It serves as a link for everything.” TECHNOLOGY photographs by RAJ CHAWLA 22 EDUCATIONAL A look at the tools that support 21st by Century education for medical students EDWARD NEUERT First-year student Adetola Fadeyibi reviews a pathology slide on COMET 23 The VIC’s hallmark is integration –— the weaving together of basic science knowledge with clinical experience. One of the tools found on COMET are case studies, such as the one these members of the Class of 2009 are seen above discussing with Associate Professor of Psychiatry and Associate Dean for Student Affairs Scott Waterman, M.D. On this day, the students in this Neural Science course first gather in the large Case Study Room (left and below) on the ground floor of the Medical Education Center to listen to and participate in a panel discussion and question-and-answer session on schizophrenia. After hearing from actual patients, family members, and a social service provider who deal with the disease on a daily basis, the students break into small groups in classrooms in the center. “The students have already reviewed the case study in the module on COMET,’ explains Waterman. “They’ve worked their way though it on their own. It comes in three installments, with questions after each section. You could think of it as an online textbook chapter on schizophrenia. This small-group session allows them to compare and contrast what they’ve learned in the study with what they’ve just heard from the personal experiences of the panel. The learning module becomes a springboard to deeper discussion and understanding.” 24 V E R M O N T M E D I C I N E For third-year student Robert Klein, seen here during a clinical rotation at the Vermont Children’s Hospital at Fletcher Allen Health Care, COMET is the main repository for the information and tools he needs every day; and it is accessible via any Internet-connected computer (and modules are downloadable to PDA devices) so that students in Burlington, at Maine Medical Center, or at any clinical setting in the world can readily access information. “Here I’m looking at the Pediatric Clinical Clerkship homepage,” explains Klein. “Basically, every course and every rotation has its own area on COMET. When you need to find readings, PowerPoints, schedules, syllabi, evaluations, etc., you go to your personal homepage, select a course or rotation and, on that homepage, there are several green tabs which take you to the various elements of that course. In the hospital I use COMET to check my daily schedule of classes and events I need to attend. I enter patient information in our clerkship interaction trackers. I access medical publications, fill out evaluations of lectures and faculty, submit assignments, find out grades… I can even look at a PowerPoint from two years ago if I need to. “I think COMET really adds to our medical education. I’d go so far as to say it’s necessary. I can’t even imagine another way of having all that information so accessible and organized.” W I N T E R / S P R I N G 2007 25 At every point we’ve “stopped and said ‘what does the curriculum need, what does the College of Medicine students regularly work with standardized patients (S.P.s), highly trained people who are expert at playing the role of patients presenting with various illnesses. Students interact with S.P.s in the exam rooms at the Student Assessment Center in the Given building. Here, second-year medical student Curtis Witcher practices an eye exam with S.P. Vivian Jordan. Behind him are related COMET learning modules. With computers in every assessment room, COMET can function as an adjunct to the S.P. presentation, by adding in pieces the S.P. cannot mimic — such as the sound of congested lungs, or an ailing heartbeat — that the student can access at the appropriate time in the assessment. “COMET is a great tool, especially when used in the setting of working with S.P.s,” says Witcher. “We get a chance to learn about a body part or system online with some helpful visual aids and then apply what we’ve learned in an actual patient encounter. Since the S.P.s have been trained in advance, they can assist us through the physical exam skills which helps solidify our knowledge of the subject matter.” 26 V E R M O N T M E D I C I N E student need, and how can we use technology to answer that need? ” — Jill Jemison (Above) One of the many people from across the College who devoted countless hours to the development of COMET, Foundations course director and Professor of Anatomy & Neurobiology and Biology Cindy Forehand, Ph.D., reviews her lecture material online with Jeff Worthley ’09. (Middle) A slide from the Virtual Microscope. (At left) COMET team members Anthony Colli, Andrew Verhelst, Judith Kessler, Cathy Ryan, and Jill Jemison. W I N T E R / S P R I N G 2007 27 HALL A The VIC ideally needed a universal testing platform, and that is what students such as the group of Class of 2008 members taking a clerkship exam in the Mimi Reardon Classroom (below) have at their disposal. (Top right, a student doing some last minute studying before taking the actual exam, middle right. While in exam mode, the student’s computers are unable to access any outside resource.) “While the VIC was in development, Cindy Forehand and Karen RichardsonNassif really pushed the idea that online exams would allow for continuous quality improvement,” explains Jill Jemison. “We’re able to standardize the test-taking format, standardize the experience of taking the exam, and then standardize the data we’re getting out of the exams.” COMET’s development has augmented the person-to-person learning experience, not replaced it. “We haven’t tried to cram in technology where it isn’t needed,” says Jemison. “There’s no ‘virtual anatomy lab,” for instance. We can’t replace the value of real dissection. At every point we’ve stopped and said ‘what does the curriculum need, what does the student need, and how can we use techVM nology to answer that need?’” P R E S I D E N T C L A S S ’ S C O R N E R 30 31 N E W S 33 38 N O T E S D E V E L O P M E N T O B I T U A R I E S In 1905, when the College of Medicine completed its third home at the corner of Prospect and Pearl streets in Burlington, the main lecture room where students spent so much of their time was named Hall A. The Hall A magazine section seeks to be a meeting place for all former students of the College of Medicine. VM 28 V E R M O N T M E D I C I N E W I N T E R / S P R I N G 2007 29 PRESIDENT ’S CORNER M.D. CLASS NOTES H A L L A H A L L A UNIVERSITY OF VERMONT COLLEGE OF MEDICINE DEVELOPMENT & ALUMNI RELATIONS OFFICE It is with great sadness that I must tell you that Patricia A. Fenn, M.D., class of 1965 and until very recently, the president-elect of your Medical Alumni Association, died on January 24th in Gladwyne, Pennsylvania of pancreatic cancer at the age of 70. She will be missed by all of us who have gotten to know and admire her as a person and as a dedicated coworker on behalf of the UVM College of Medicine and the Medical Alumni Association. Pat’s classmates undoubtedly will be most deeply moved upon learning of her passing, as have her relatives, her many friends and colleagues in Pennsylvania. Pat’s obituary can be found among those of several other alumni and friends — too many — in this section of the magazine. Of course, most of you who are reading this column did not know Pat, but those of you who did will remember her as a singularly gentle and kind woman who approached her professional life in the same way that she conducted her personal relations. Not one to trumpet her significant accomplishments, Pat nevertheless quickly became respected and loved by those who worked with her. A native Vermonter (Bellows Falls), she graduated from UVM with a B.A. in zoology before joining her medical school class as one of its very few female students at that time. Following graduation from medical school, Pat went to Bryn Mawr Hospital in Pennsylvania for her training in internal medicine and on to a rheumatology fellowship at Temple University. A superb clinician, she joined the staff of Bryn Mawr Hospital, rising to become its Chief of Service of Rheumatology and Director of the Arthritis and Orthopedic Center, serving on the medical faculty of Thomas Jefferson University as well. In 2005 Pat received the A. Bradley Soule Award, the highest honor that the UVM College of Medicine grants to its alumni. In his citation when Pat was given that award, John P. Tampas, M.D. ’54 noted how she had maintained her close links to UVM, where she served on the University’s Alumni Council and chaired its Education Committee. For many years, she was an active member of the Medical Alumni Association, worked on its Planned Giving Committee and where I got to know her, on the Alumni Executive Committee. A member of the Wilbur Society, Pat supported the College of Medicine generously, establishing a Medical Alumni Association Term Scholarship for students and contributing funds for classroom 201, which was named for her in the new Medical Education Center. Pat’s last months were spent facing her illness and its arduous treatment with stoicism and resolve. In my last conversation with her, she acknowledged that the treatments had been difficult, but that she was managing pretty well. She also asked me to send her regards to my wife, whom she said she always enjoyed being with in Burlington when we would get together. That was typically Pat. Marv Nierenberg, M.D.’60 30 V E R M O N T M E D I C I N E ASSISTANT DEAN rick blount DEVELOPMENT OPERATIONS MANAGER ginger lubkowitz DIRECTOR , MAJOR GIFTS manon o ’ connor DIRECTOR , MEDICAL ANNUAL GIVING sarah keblin DIRECTOR , MEDICAL ALUMNI RELATIONS cristin gildea DEVELOPMENT OFFICER travis morrison ASSISTANTS jane aspinall james gilbert todd stewart UNIVERSITY OF VERMONT MEDICAL ALUMNI ASSOCIATION ALUMNI EXECUTIVE COMMITTEE 2006–2007 OFFICERS TERMS ) PRESIDENT ( TWO -YEAR marvin a. nierenberg, m.d.’60 (2006-2008) PRESIDENT- ELECT ruth a. seeler, m.d.’62 (2006-2008) SECRETARY james c. hebert, m.d.’77 (2006-2008) EXECUTIVE SECRETARY john tampas, m.d.’54 (ongoing) MEMBERS - AT- LARGE : (6-YEAR TERMS ) leslie s. kerzner, m.d.’95 (2002-2008) frederick mandell, m.d.’64 (2002-2008) don p. chan, m.d.’76 (2002-2008) mark allegretta, ph.d.’90 (2003-2010) mark pasanen, m.d.’92 (2004-2010) h. james wallace, iii, m.d.’88 (2004-2010) naomi r. leeds, m.d., ’00 m.p.h. (2004-2010) paul b. stanilonis, m.d.’65 (2006-2012) carleton r. haines, m.d. ’43 (2006-2012) jacqueline a. noonan, m.d. ’54 (2006-2012) If you have news to share, please contact your class agent or the alumni office at [email protected] or (802) 656-4014. If your email address has changed, please send it to: [email protected]. 1937 Nathaniel Gould writes: “We are now in a retirement home in Birmingham, Alabama. Best wishes to all!” 1941 John S. Poczabut 62 Doral Farm Road Stamford, CT 06902 (203) 322-3343 1943 Francis Arnold Caccavo (M.D. Dec. 1943) 51 Thibault Parkway Burlington, VT 05401 (802) 862-3841 Carleton R. Haines (M.D. Dec. 1943) 88 Mountain View Road Williston, VT 05495 (802) 878-3115 Harry M. Rowe (M.D. March 1943) 65 Main Street P.O. Box 755 Wells River, VT 05081 (802) 757-2325 [email protected] 1944 Wilton W. Covey 357 Weybridge Street Middlebury, VT 05753 (802) 388-1555 1945 Robert E. O’Brien 414 Thayer Beach Road Colchester, VT 05446 (802) 862-0394 [email protected] H. Gordon Page 9 East Terrace South Burlington, VT 05403 (802) 864-7086 1946 J. Bishop McGill 152 Sanborn Road Stowe, VT 05672 (802) 253-4081 [email protected] R E U N I O N Richard E. Pease P.O. Box 14 Jericho, VT 05465 (802) 899-2543 Edward S. Sherwood 24 Worthley Road Topsham, VT 05076 (802) 439-5816 [email protected] March 15, 2007 Match Day College of Medicine Campus April 20, 2007 American College of Physicians Reception, Marriott, San Diego, Calif. Simon Dorfman 8256 Nice Way Sarasota, FL 34238 (941) 926-8126 ’ 0 7 George H. Bray 110 Brookside Road New Britain, CT 06052 (860) 225-3302 Porter H. Dale 5 McKinley Street Montpelier, VT 05602 (802) 229-9258 Thomas Holcomb says he and his wife, Eleanor are “starting to come apart, but hope we can find enough replacement parts to let us get to our 60th Reunion!” 1948 S. James Baum 1790 Fairfield Beach Road Fairfield, CT 06430 (203) 255-1013 [email protected] 1949 James Arthur Bulen 4198 North Longvalley Rd. Hernando, FL 34442 (352) 746-4513 [email protected] 1951 Edward W. Jenkins 7460 South Pittsburg Ave. Tulsa, OK 74136 (918) 492-7960 R E U N I O N UPCOMING EVENTS March 14, 2007 Class of 2007 Dinner Emerald Ballroom, Sheraton Burlington Burlington, Vt. 1950 1947 Joseph C. Foley 32 Fairmount Street Burlington, VT 05401 (802) 862-0040 [email protected] ’ 0 7 1952 Brewster Davis Martin Box 128 362 VT Route 110 Chelsea, VT 05038 (802) 685-4541 May 5, 2007 Alumni Executive Committee Meeting UVM College of Medicine May 20, 2007 Medical Commencement Ira Allen Chapel June 8-10 2007 2007 Medical Reunion UVM College of Medicine For updates on events see: www.med.uvm.edu/medalum 1953 (802) 864-4927 [email protected] Richard N. Fabricius 17 Fairview Road Old Bennington, VT 05201 (802) 442-4224 [email protected] 1956 1954 John E. Mazuzan, Jr. 366 South Cove Road Burlington, VT 05401 (802) 864-5039 [email protected] 1955 Marshall G. London 102 Summit Street Burlington, VT 05401 Ira H. Gessner 1306 Northwest 31st Street Gainesville, FL 32605 (352) 378-1820 [email protected] R E U N I O N ’ 0 7 1957 Larry Coletti 34 Gulliver Circle Norwich, CT 06360 (860) 887-1450 [email protected] W I N T E R / S P R I N G 2007 31 M.D. CLASS NOTES H A L L A Sanford Bloomberg selfpublished his autobiography in 2004, which includes his experiences at the College of Medicine. 1958 Peter Ames Goodhue Stamford Gynecology, P.C. 70 Mill River Street Stamford, CT 06902 (203) 359-3340 1959 Jay E. Selcow 27 Reservoir Road Bloomfield, CT 06002 (860) 243-1359 [email protected] R E U N I O N 1962 G. Millard Simmons 3165 Grass Marsh Drive Mount Pleasant, SC 29466 [email protected] 1963 R E U N I O N John J. Murray P.O. Box 607 Colchester, VT 05446 (802) 865-9390 [email protected] H. Alan Walker 229 Champlain Drive Plattsburgh, NY 12901 (518) 561-8991 [email protected] 1964 Marvin A. Nierenberg 6 West 77th Street New York, NY 10024 (212) 874-6484 [email protected] Anthony P. Belmont 211 Youngs Point Road Wiscasset, ME 04578 (207) 882-6228 [email protected] Melvyn H. Wolk Clinton Street P.O. Box 772 Waverly, PA 18471 (570) 563-2215 [email protected] Lester H. Wurtele, Jr. is still practicing radiology three days per week. He and his wife, Irma, have “two wonderful grandchildren and get back to Vermont at least once a year.” Wilfrid L. Fortin 17 Chapman Street Nashua, NH 03060 (603) 882-6202 [email protected] John M. McGinnis writes: “Forty-nine years after being a first year med student I am meeting the class of 2010 as a standardized patient in their doctoring skills class.” 1965 George A. Little 97 Quechee Road Hartland, VT 05048 (802) 436-2138 george.a.little@ dartmouth.edu Joseph H. Vargas III 574 US Route 4 East Rutland Town, VT 05701 (802) 775-4671 [email protected] 1966 Robert George Sellig 31 Overlook Drive V E R M O N T M E D I C I N E Queensbury, NY 12804 (518) 793-7914 [email protected] Ruth Andrea Seeler 2431 North Orchard Chicago, IL 60614 (773) 472-3432 [email protected] 1960 1961 32 ’ 0 7 and service to the community bring honor upon themselves and Northeastern.” 1968 1967 David Jay Keller 4 Deer Run Mendon, VT 05701 (802) 773-2620 [email protected] John F. Dick II P.O. Box 60 Salisbury, VT 05769 (802) 352-6625 Timothy John Terrien 14 Deerfield Road South Burlington, VT 05403 (802) 862-8395 ’ 0 7 Ursel Danielson writes: “Life is good. First grandson started college at USC and granddaughter is working on her driver’s license. I am looking forward to seeing our class this coming spring.” Mimi Reardon received a 2006 Outstanding Alumni Award from Northeastern University at a ceremony held Oct. 20. Mimi graduated from Northeastern in 1963 with a degree in biology. She was honored for her many accomplishments and community service, including the establishment of the first Area Health Education Centers program in Vermont, her role in promoting rural health education and health care careers in Vermont, as well as her work to identify funding for loan repayment aid for Vermont health care professionals practicing in underserved areas. First presented in 1978, Northeastern's Outstanding Alumni Awards are given annually to “those graduates whose professional attainment DEVELOPMENT NEWS Professor of Surgery Steven Shackford, M.D. and Samuel B. Labow, M.D. group of institutions to earn designation as a National Cancer Institute-designated center. Now — with the genIrwin H. Krakoff M.D. erous support of the Lake Champlain Cancer Research Organization and numerous other friends, colleagues and family — the VCC is paying tribute to its founding director by announcing completion of funding for the Irwin H. Krakoff, M.D. Green & Gold Professor at the VCC. The honor is expected to be awarded to one of the next generation of physician-scientists who will carry on Krakoff’s legacy. Krakoff remains active in VCC affairs, advising the leadership on the future of the center. LABOWS FUND NEW SURGERY LECTURESHIP 1969 Susan Pitman Lowenthal 200 Kennedy Drive Torrington, CT 06790 (860) 597-8996 susan_w_pitmanlowen [email protected] 1970 Raymond Joseph Anton 1521 General Knox Road Russell, MA 01071 (413) 568-8659 [email protected] John F. Beamis, Jr. 24 Lorena Road Winchester, MA 01890 (781) 729-7568 [email protected] 1971 Wayne E. Pasanen 117 Osgood Street North Andover, MA 01845 (978) 681-9393 wpasanen@lowell general.org R E U N I O N 1972 F. Farrell Collins, Jr. 205 Page Road Pinehurst, NC 28374 (910) 295-2429 ’ 0 7 A Stowe, Vt. couple who have formed strong ties to the Department of Surgery at the College of Medicine has funded a new annual lecture at the College with their recent pledge of $250,000. Dr. Samuel B. and Michelle D. Labow pledged current and estate gifts in excess of $5 million in the past year. Their initial gift funded the Samuel B. and Michelle D. Labow Green & Gold Professor in Colon & Rectal Surgery and the Labow Lectureship in Colon & Rectal Surgery. The new Shackford/ Labow Lecture in Surgery is named in honor of Professor of Surgery Steven Shackford, M.D., who was chair of the Department of Surgery from 1990 to 2007. The inaugural Labow/ Shackford lecture will take place June 28. CRANE CHALLENGE HELPS PROPEL MED FUND Donations to the UVM College of Medicine Fund for fiscal year 2007 are off to a great start. Director of Annual Giving Sarah Keblin reports that nearly $400,000 has already been raised for the annual fund. The kickoff of the newly-renamed and reorganized fund has been highly successful, due in large part to the challenge fund created by alumnus Edward Crane, M.D.’47. Dr. Crane’s challenge gift matches new and increased gifts from his fellow graduates. The Med Fund has attracted more than 1100 donors as of February 15, a more than 25% increase over prior years’ annual giving rates, and has seen significant numbers of new and recent-alumni donors. KRAKOFF HONORED WITH GREEN AND GOLD Under the leadership of Irwin H. Krakoff, M.D., the Vermont Cancer Center in 1978 became one of an elite TOP LEFT AND RIGHT: UVM MEDICAL PHOTOGRAPHY SCOTT AND KIM IRELAND : A COMMITMENT TO CANCER RESEARCH This St. Patrick’s Day, the trucks of the S.D. Ireland Construction Corp. roll through the streets of Burlington on parade. The twenty-year tradition of the company now celebrates not only the Irish heritage of the company’s founders, but also the Ireland family’s commitment to cancer research at the Vermont Cancer Center. Scott and Kim Ireland know first-hand about those efforts. Scott is a survivor of melanoma, and he credits his survival in a large part to the care provided him by Professor of Surgical Oncology David M. Krag. S.D. Ireland Corp. fundraising efforts, including money collected during the St. Patty’s Parade, now support Dr. Krag’s extensive cancer research through the S.D. Scott and Kim Ireland Ireland Cancer Research Foundation. The Irelands are also working with the College on additional fundraising to support breast cancer research at the Vermont Cancer Center. WOLKS SUPPORT PEDIATRIC RESEARCH AND EDUCATION Melvyn H. Wolk, M.D.’60 and Marilyn K. Wolk have provided the College with a $650,000 charitable remainder trust to fund the Wolk Research & Education Fund in Pediatrics. Dr. Wolk is a retired pediatrician and pediatric allergist. The Wolks’ son, Larry, is a 1988 graduate of the College. W I N T E R / S P R I N G 2007 33 M.D. CLASS NOTES H A L L A VERMONT PHYSICIAN OF THE YEAR For her outstanding service to the Vermont medical community, the Vermont Medical Society has presented Suzanne Parker, M.D.’73 of Charlotte with its 2006 Physician of the Year Award. Dr. Parker, a psychiatrist with a private practice in Burlington, is a leader in the field of addictionology. Dr. Parker was a founder of the Vermont Practitioner Health Program, and served as its medical director until recently. She also helped to launch Suzanne Parker, M.D. ’73 practitioner wellness programs at the Medical Center Hospital of Vermont and at the College of Medicine. Before moving back to Vermont in 1987, Dr. Parker was the psychiatric director of the Department of Substance Abuse at Henry Ford Hospital in Detroit, Mich. “Dr. Parker has been a prime force behind the establishment of an effective program to support the recovery of Vermont physicians and she has been tirelessly dedicated to the treatment of the suffering physician,” said Dr. Peter Dale, immediate past president of the Vermont Medical Society. “Dr. Parker has been an inspiration to all of those who were fortunate to work with her on helping lead physicians to recovery.” The Physician of the Year Award is given to a Vermont physician who has demonstrated outstanding performance in the quality of care given to his or her patients, demonstrated skillful and compassionate patient care, and has demonstrated dedication to the welfare of his or her patients in accordance with accepted principles of good medical practice. 34 1973 1974 James M. Betts 715 Harbor Road Alameda, CA 94502 (510) 523-1920 [email protected] Douglas M. Eddy 5 Tanbark Road Windham, NH 03087 (603) 434-2164 [email protected] Philip L. Cohen 483 Lakewood Drive Winter Park, FL 32789 (407) 628-0221 [email protected] Cajsa Schumacher 78 Euclid Avenue Albany, NY 12203 [email protected] V E R M O N T M E D I C I N E Constance Passas is enjoying life on the beautiful seacoast of N.H. She is in a full-time, very busy and challenging rheumatology practice. She would welcome contact from any classmates: 603-430-8333. 1975 Ellen Andrews 195 Midland Road Pinehurst, NC 28374 (910) 295-6464 [email protected] 1978 Paul McLane Costello Essex Pediatrics, Ltd. 89 Main Street Essex Junction, VT 05452 (802) 879-6556 1976 Don P. Chan Cardiac Associates of New Hampshire Suite 103 246 Pleasant Street Concord, NH 03301 (603) 224-6070 [email protected] R E U N I O N Alexandria is in her first year at Brown, studying music and medical anthropology. Gail is busy doing general internal medicine, chairing George Washington’s ethics committee and traveling with her husband, Larry. 1979 Sarah Ann McCarty 1018 Big Bend Road Barboursville, WV 25504 (304) 691-1094 [email protected] ’ 0 7 1977 1980 Mark A. Popovsky 22 Nauset Road Sharon, MA 02067 (781) 784-8824 mpopovsky@ haemonetics.com Richard Nicholas Hubbell 80 Summit Street Burlington, VT 05401 (802) 862-5551 rich.hubbell@ vtmednet.org Allan Freedman writes: “I am still in Atlanta, Georgia, now approaching 30 years and enjoying the practice of hematologyoncology more than ever now that there are seven doctors in the group. This specialty is constantly challenging, evolving and rewarding, but I am still finding extra time to ride my bike, play tennis and otherwise enjoy the sunny South.” Gail Povar writes that her son Justin has graduated from Brown University and has a neuroscience research job in Boston. Daughter Sarita H. Brouwer writes: “I have found my medical ‘home’ caring for our retired soldiers at the Boston VA Hospitals, as an anesthesiologist. Daughters: Rachel applying to med schools; Rebekah is in college. David Diamond is my love.” 1981 Craig Wendell Gage 2415 Victoria Gardens Tampa, FL 33609 CraigGage@ alumni.uvm.edu David P. Meeker, who is president of the Lysosomal Storage Diseases Therapeutics business unit of Danbury, Conn.-based Genzyme Corporation, has been named to the company’s board of directors. During his leadership of the business unit, he has held development responsibility for its therapeutics portfolio, and global responsibility for three marketed enzyme replacement products which have generated over one billion dollars in revenue. He joined Genzyme in 1994. R E U N I O N ’ 0 7 1982 Linda Hood 4 Cobbler Lane Bedford, NH 03110 (603) 471-2536 [email protected] Martha McCarty’s oldest daughter is a sophomore at Bowdoin College and her youngest is a senior in high school. Martha is busy with private practice and is chair of the pediatrics department at Winchester Hospital in Massachusetts. 1983 Diane M. Georgeson 2 Ravine Parkway Oneonta, NY 13820 (607) 433-1620 [email protected] Anne Marie Massucco 15 Cedar Ledge Road West Hartford, CT 06107 (860) 521-6120 [email protected] Ronald Hartfelder is doing well in Salem, Mass. He is now the medical director of endoscopy at North Shore Medical Center. CONTINUING MEDICAL EDUCATION 1984 2007 CONFERENCE SCHEDULE Richard C. Shumway 34 Coventry Lane Avon, CT 06001 (860) 673-6629 rshumway@ stfranciscare.org 12th Annual Vermont Perspectives in Anesthesia March 7-11, 2007, Stoweflake Resort, Stowe, Vt. Susan Pories writes: “I have been privileged to work with the Harvard medical students on medical narrative writing and the humanities. Our first book, The Soul of a Doctor was published in June 2006. I’d love to hear from other UVM physicians involved in similar endeavors: spories@BIDMC. harvard.edu 1985 Vito D. Imbasciani 1915 North Crescent Heights Blvd. Los Angeles, CA 90069 (323) 656-1316 [email protected] 1986 Darrell Edward White 29123 Lincoln Road Bay Village, OH 44140 (440) 892-4681 [email protected] 1987 Michael J. Kaplan has five beautiful children, ages 9, 9, 9, 7 and 3. He has a busy knee and shoulder orthopaedic practice, is an instructor at Yale University Department of Orthopaedics, is an ESPN medical correspondent and a program chairman for the The Stowe Conference on Digestive Diseases March 8-10, 2007, Topnotch Resort, Stowe, Vt. Vermont Blueprint for Health – Chronic Care Conference April 20, 2007, Sheraton Hotel, Burlington, Vt. Child Psychiatry for the Primary Care Clinician May 3–5, 2007, Wyndham Hotel, Burlington, Vt. Women’s Health: Perception, Prevention and Practice May 9–11, 2007, Sheraton Hotel, Burlington, Vt. Family Medicine Review Course June 5–8, 2007, Sheraton Hotel, Burlington, Vt. Vermont Summer Pediatric Seminar June 14–17, 2007, The Equinox, Manchester, Vt. Advanced Dermatology for The Primary Care Physician September 6–9, 2007, Samoset Resort, Rockport, Maine Dementia & Geriatric Neuropsychiatry Conference September 14–16, 2007, Stoweflake Resort, Stowe, Vt. Primary Care Sports Medicine September 26–28, 2007, Sheraton Hotel, Burlington, Vt. 21st Annual Imaging Seminar October 12–14, 2007, Stoweflake Resort, Stowe, Vt. 5th Annual Northern New England Critical Care Conference October 18–20, 2007, Stoweflake Resort, Stowe, Vt. Northern New England Neuroimmunology Symposium October 26–28, 2007 Trapp Family Lodge, Stowe, Vt. College of Medicine alumni receive a special 10% discount on all UVM Continuing Medical Education conferences. For information contact: University of Vermont Continuing Medical Education 128 Lakeside Avenue Suite 100 Burlington, VT 05405 (802) 656-2292 http://cme.uvm.edu M.D. CLASS NOTES H A L L A Connecticut Orthopaedic Society. Cate McKegney writes: “Our 25th reunion was great — seeing my classmates. After my father’s death in February and hearing how much he meant to his former students reminded me that true teachers live on long after their lifetimes end.” R E U N I O N ’ 0 7 1988 H. James Wallace III 416 Martel Lane St. George, VT 05495 (802) 872-8533 james.wallace@ vtmednet.org Lawrence I. Wolk 5724 South Nome Street Greenwood Village, CO 80111 (303) 771-1289 lawrence.wolk@ cigna.com 1989 Peter M. Nalin 13216 Griffin Run Carmel, IN 46033 (317) 962-6656 [email protected] Dean G. Mastras writes: “Julie, Kassie, Izzie and I are enjoying the skiing. It’s another record snowfall in the Cascades. We are finishing up our Mt. Retreat at Lake Wenatchee and busy opening up a new office in Olympia Wash. Not many UVM Alumni in the area so we would love to hear from you!” Peter Nalin received the A. Alan Fischer Award from the Indiana Academy of Family Physicians. It recognizes members who in the opinion of the Board of Directors of the IAFP 36 V E R M O N T M E D I C I N E have made outstanding contributions to education for family medicine, in undergraduate, graduate and continuing education spheres. Michael Rousse writes: “Ginger and I are hanging out in the hills of Danville, Vt., on our minifarm. We put up over 2000 bales of hay this summer — ready for winter. I am now the medical director of corrections in the state of Vermont — something a little different. Durham, CT 06422 (860) 349-6941 1990 Anjulika Chawla is a professor at Brown University and is working at Hasbro Children’s Hospital as a pediatric oncologist. Barbara Angelika Dill 120 Hazel Court Norwood, NJ 07648 (201) 767-7778 [email protected] 1991 John Dewey 15 Eagle Street Cooperstown, NY 13326 [email protected] K.A. Kelly McQueen is still in Arizona, practicing part-time anesthesia and part-time public health. R E U N I O N ’ 0 7 1992 Mark Eliot Pasanen 1234 Spear Street South Burlington, VT 05403 (802) 865-3281 mark.pasanen@ vtmednet.org Katherine Ray is enjoying practicing child and adolescent psychiatry in Portland, Maine. 1993 Joanne Taplin Romeyn 22 Patterson Lane 1994 Holliday Kane Rayfield P.O. Box 819 Waitsfield, VT 05673 (802) 496-5667 [email protected] 1995 Allyson Miller Bolduc 252 Autumn Hill Road South Burlington, VT 05403 (802) 863-4902 allyson.bolduc@ vtmednet.org 1996 Anne Marie Valente 4616 Dolwick Drive Durham, NC 27713 (919) 806-8110 [email protected] Patricia Ann King, M.D., Ph.D. 832 South Prospect Street Burlington, VT 05401 (802) 862-7705 patricia.king@ vtmednet.org R E U N I O N ’ 0 7 1997 Julie Clifford Smail 10 Proctor Street Manchester-by-the-Sea, MA 01944 (360) 240-8693 jsmail@ fidalgomedical.com Alexander Hughes writes: “Post fellowship I have spent the last four-andone-half years at Vanderbilt University. I am currently an assistant professor in the pediatric cardiothoracic division. At home, Brenda and I have our hands full with Andrew (12), Emily (8) and Matthew (1). 1998 Halleh Akbarnia 4700 Bromley Lane Richmond, VA 23226 (804) 204-2595 [email protected] 1999 Everett Jonathan Lamm 11 Autumn Lane Stratham, NH 03885 (603) 929-7555 [email protected] Deanne Dixon Haag 4215 Pond Road Sheldon, VT 05483 (802) 524-7528 Jason Cook is currently in his second year of his pediatric critical care fellowship at Mass General Hospital. David J. Finley writes that he is currently a thoracic surgery fellow at Memorial Sloan Kettering Cancer Center in his first year. His wife, Jennifer, is in her second year of surgical research and will be returning to NYU to finish her general surgery residency. Their son Nathaniel Finley is now 14 months old. David Lindquist writes: “We are settled in Rhode Island. Who’d’a thunk it? Eva turns 9 in January, Axel is 6. Jen is bucking for associate professor at Brown. I started as the assistant program director for the Department of Emergency Medicine this fall. Stop by, and we’ll paddle on the bay.” Peter James Swarr married Elizabeth Brice Calhoun in April 2006 in Cheraw SC. Fellow Vermont alum Dr. Ram Anand Narasimhan ’99 served as a groomsman. The Swarr’s make their home in Nashville, Tenn. Peter is a partner of Cool Springs Internal Medicine and Pediatrics, assistant professor at Vanderbilt University, and Elizabeth is a senior consultant for the Vanderbilt Center for Better Health. 2000 Jay Edmond Allard USNH Yokosuka PSC 475 Box 1757 FPO, AP 96350 [email protected] Michael Jim Lee 71 Essex Lane Irvine, CA 92620 michael_j_lee1681@ yahoo.com 2001 Ladan Farhoomand 1481 Regatta Road Carlsbad, CA 92009 (626) 201-1998 [email protected] Joel W. Keenan Greenwich Hospital Five Perryridge Road Greenwich, CT 06830 [email protected] JoAn Louise Monaco Suite 6-F, 5E 4618 Warwick Blvd. Kansas City, MO 64112 (816) 753-2410 [email protected] Stephan Hatch writes: “Kathryn Masselam and I are engaged, and plan to wed next summer in Manchester, Vt. Otherwise KIERNAN SPEAKS ON ‘ LAST RIGHTS ’ DURING PALLIATIVE CARE WEEK Vermont writer and former Burlington Free Press staff member Stephen Kiernan spoke at the College of Medicine on January 24 as part of a week of lunchtime presentations and discussions organized by the Palliative Care Student Interest Group. Kiernan is the author of Last Rights: Rescuing the End of Life from the Medical System, a book recently published by St. Martin’s Press. Several people connected with the College were interviewed as part of Kiernan’s research for the book, including the late Bruce Fonda, Associate Professor of Psychiatry Terry Rabinowitz, M.D., Clinical Associate Professor of Medicine Zail Berry, M.D., Professor of Family Medicine Allan Ramsay, M.D., Clinical Professor of Family Medicine Robert Orr, M.D., and Abigail Donaldson, M.D.’06. After an introduction by Interim Dean John P. Fogarty, M.D., Kiernan spoke about the ways, over the past three decades, that medical advances have extended lives and changed the way we die. He spoke about the disconnect that can still exist between the way patients desire to live the end of life, and how much of the medical system continues to treat the dying. Palliative Care Week also featured presentations by Dr. Berry, by Brookes Cowan, Ph.D., Robert Macauley, M.D., and others. I am in practice in Stonington, Conn., and Kathryn finishes up her optho residency next June. I hope all is well up in Vermont. I sure do miss those beautiful summers up there.” R E U N I O N ’ 0 7 2002 Jonathan Vinh Mai 15 Meadow Lane Danville, PA 17821 (570) 275-4681 [email protected] Thuan T. Nguyen finished residency last year and moved from Philadelphia to Phoenix. He is newly single, but enjoying life. He works in a small community hospital that sees some interesting stuff and has run in a marathon and is training for another in January. 2003 Omar Khan 33 Clearwater Circle Shelburne, VT 05482 (802) 985-1131 [email protected] Scott Goodrich 13 Mountain View Blvd. South Burlington, VT 05403 (802) 864-7787 [email protected] Rima B. Carlson graduated from a family practice residency and started serving her National Health Service Corps. obligation at a small hospital in Hancock, MI. She and her husband are expecting a child in April and are in the process of adopting a girl from Haiti. 2004 Jillian S. Geider jillian.geider@ vtmednet.org Emily A. Hannon emily.hannon@ hsc.utah.edu Steven D. Lefebvre fabulous5lefebvre@ hotmail.com Laura (Howard) Leduc had a daughter, Tessa, born June 13, 2006. Bryan Suchecki, writes: “I finished my internship at the National Naval Medical Center in Bethesda, Maryland. For the next two years, I will be the flight surgeon for a helicopter training squadron in Pensacola, and then will look to return to UVM as a resident. 2005 Julie A. Alosi [email protected] Richard J. Parent [email protected] 2006 William C. Eward [email protected] Deborah Rabinowitz debbie.rabinowitz@ uvm.edu W I N T E R / S P R I N G 2007 37 OBITUARIES H A L L A JOHN T. WRIGHT, M . D.’41 Dr. Wright, of Tampa, Fla., died January 4, 2007. He was 93. Dr. Wright completed his undergraduate studies at Norwich University and before receiving his medical degree from UVM in 1941. He served with the U.S. Army Medical Corps from 1941-1946, and retired as a lieutenant colonel. Dr. Wright ran his medical practice in Tampa for more than 30 years, during which time he was instrumental in the creation of University Community Hospital, where he served as the first chief of staff. EDNA DOLE BACKUP, M . D.’46 Dr. Backup died at Wake Robin in Shelburne, Vt., on July 31. She was born Aug. 3, 1914, on a hilltop farm in Proctorsville, Vt., the second of four daughters of Fletcher Enos Dole and Laura Rogina Harrington. Dr. Backup graduated from Simmons College in 1936, with a B.S. in chemistry and biology. She worked as a medical technologist until 1943, when the physicians she worked for in St. Johnsbury helped her go to medical school. She graduated from the College of Medicine, cum laude. Dr. Backup and her husband, UVM classmate Phil Backup, moved to Tacoma, Washington, for their internships. They raised three daughters in Tacoma. Dr. Backup moved back to Vermont in 2001. FREDERICK PRATT, M . D.’53 Frederick Pratt, M.D.’53 38 Dr. Frederick Pratt died August 25, 2006, in his home in Sacramento, Calif. Born in North Clarendon, Vt., on August 18, 1926, he was the son of Roy and Mary Pratt. A World War II veteran, he attended the University of Vermont on the G.I. bill, graduating in 1950 with a Bachelors of Science before entering the College of Medicine. During medical school he met and married Anna Temple V E R M O N T M E D I C I N E Condos (Dr. Anna Pratt, pathologist, Travelers Insurance Company in deceased 1974). In 1954 he moved to 1990 as vice president and chief medFolsom, Calif., and began his career ical director. as a general practitioner. After four years of practice Dr. Pratt PATRICIA A . returned to the east coast to FENN , M . D.’65 complete a residency in plastic Dr. Fenn was born and reconstructive surgery at on Sept. 21, 1936, Upstate New York Medical in Bellows Falls, Center, Syracuse. He returned Vt., and died Jan. to Sacramento, Calif., in 1962 24, 2007, in Bryn Mawr Hospital, and began a private practice in Bryn Mawr, Penn. plastic surgery. Dr. Pratt was Patricia A. Fenn, She was educated also an assistant clinical proM.D.’65 in the Vermont fessor, Department of Plastic Surgery, University of California public schools and received her B.A. Davis School of Medicine and found- from UVM 1959 before earning her ed the Sutter Cleft Palate and M.D. At the time of her death, her Orofacial Anomaly Panel, Sacra- specialization was in internal medimento. He married his second wife cine, rheumatology. Dr. Fenn joined Patricia, a surgical nurse, in May of the staff of Bryn Mawr Hospital in 1976. After 25 years Dr. Pratt July 1969 and continued on staff there “retired” from private practice to for the rest of her life. She also served begin a second career of volun- as senior attending rheumatologist teerism. This career took Dr. Pratt to from July 1985 to 2007. She was chief the far reaches of the globe to help of service of rheumatology at Bryn those most in need of medical care. Mawr Hospital from July 1985 until He was also committed to local July 1992, was the medical director of health activities. the Bryn Mawr Hospital Arthritis and Orthopedic Center from August 1989 JOSEPH R . JURKOIC , M . D.’60 to September 1995, and was a Dr. Jurkoic died on June 23, 2006 at rheumatology consultant at Bryn his home in East Berlin, Conn. after Mawr Rehabilitation Hospital from a long illness. He was 75. He was July 1986 until her death. She born in Bellows Falls, Vt., where he received the Main Line Health completed his high school education. System “Helmsman Award for OutFollowing high school he joined the standing Physician Leadership“ in United States Navy and served in the November 1994. Dr. Fenn was a medical corps from 1948-1952. Upon member of the UVM College of leaving the service he completed col- Medicine Planned Giving Committee lege and medical school at UVM. from 1995 to 2002, a member of the After serving his internship at the UVM Alumni Council from 1995 to Bishop DeGoesbriand Hospital in 2001, and chairwoman of the UVM Burlington, he completed a two year Alumni Council from 1995 to 2001. residency at the University of Ver- She was a member of the College of mont. In 1963 he entered a private Medicine Alumni Executive Commitpractice of Pediatrics in New Britain, tee from 1996 to 2002, and treasurer Conn., and in 1970 became Chief of of the committee from 2002 to 2006. Pediatrics at New Britain General In 2005, the Medical Alumni AssociaHospital with a faculty appointment tion awarded her the A. Bradley Soule at the University of Connecticut Award, the highest alumni honor College of Medicine. He completed bestowed by the College of Medicine. his professional career at the CHARLES M . D ’ANGELO, M . D. ‘68 Dr. D’Angelo, formerly of Chicago, died on October 30 at his home in Dodgeville, Wisconsin of malignant insulinoma, an extremely rare type of cancer. He was a board-certified neurosurgeon and practiced for 25 Years at Rush Medical College in Chicago, specializing in microscopic surgery for aneurysms and pituitary tumors. For several years Chicago magazine listed him among Chicago’s best neurosurgeons. He greatly enjoyed mentoring nurses, medical students, and residents. In 1964 he married his high school sweetheart, Betsy Curtis. His greatest pride and joy came from being a father to their daughter, Cara Catarina D’Angelo, who died of cystic fibrosis in 1978 at the age of eight. JAMES E . EMMONS M . D.’68 Dr. Emmons died May 29, 2006 in Cottonwood, Arizona after a brief battle with cancer. He was born July 9, 1935. In 1958, Dr. Emmons graduated from the U.S. Military Academy at West Point. After the completion of Ranger training and Airborne Jump School, he was stationed in Europe with the U.S. Army. After serving several years with the Army Tank Corps in Bad Hersfeld, Germany, he left the military to attend medical school.. He completed his residency at the University of Michigan Medical School in 1973. In 1974, Dr. Emmons moved his family to the Verde Valley of Arizona, where he established Verde Valley Urology in Cottonwood. He was a surgeon at the Marcus J. Lawrence Medical Center and served two terms as the chief of staff. Dr. Emmons retired from practicing medicine in 1998. Dr. Emmons commitment to duty continued to be strong as he began his career as a combat surgeon in the U.S. Army Reserve from 1977 to 1995. FACULTY WILLIAM VAN B . ROBERTSON , M . D. WILLIAM A . TISDALE , M . D. William Van Bogaert Robertson passed away in northern California on May 7, 2006 at the age of 91. “Van” or “Robbie” as everyone called him was professor of biochemistry and experimental medicine at the College of Medicine from 1945 to 1961. Students remembered his formidable lectures on the Krebs cycle inside the classroom. Outside, however, his good humor, delight in discussion over a beer, his widespread knowledge, his integrity, and his strength and abandon on the ski-trail seemed more important and durable. His informal influence on many of his students was profound. His counsel and insight helped form many medical and scientific career decisions. His defense with his colleague Arnold Schein of Alex B. Novikoff, professor of pathology at UVM during the McCarthy Era aligned him with Archbishop Robert Joyce of the Catholic Diocese of Vermont, Rabbi Max Wall of Burlington, and many other religious leaders and statesmen who affirmed his defense of academic freedom versus political expediency. Only many years later was Novikoff reinstated at UVM and given an honorary degree. Some of Robertson’s ideas on curriculum innovation have since been adapted by the College. He left UVM for a second distinguished career at Stanford Medical School, where he continued to teach and do research in mucopolysaccharide metabolism. — by Arthur Kunin, M.D.’52 William Allan Tisdale, M.D., died on Sunday, Nov. 12, 2006, in the Vermont Respite House in Williston. He was born in Quincy, Fla. on Feb. 14, 1928. He graduated from the University of Florida in 1947 and the Harvard Medical School in 1951, and served as a medical officer in the U.S. Army during the Korean conflict. He completed an internship and residency in internal medicine at Massachusetts General Hospital, where he met his future wife Nancy. He then completed a research fellowship in hepatology at Yale University School of Medicine. At Yale, he was also an Instructor in Medicine and in 1959 was the recipient of the Francis Gilman Blake Award given by the senior class to the most outstanding teacher in the medical sciences. He then returned to Boston as Instructor in Medicine at Harvard Medical School and Research Fellow at the Medical Foundation. In 1965 he became Associate Professor of Medicine at Dartmouth Medical School and Director of Medical Education. He came to Burlington in 1965 as Professor of Medicine and Chairman of the Department of Medicine until 1974. He founded the Geriatrics Unit at the College of Medicine in 1978 and served as its Director until his retirement in 1994. He received the Teacher of the Year award in 1985, and also served as Medical Director at the Burlington Health and Rehabilitation Center. After retiring from the College of Medicine, he worked as a medical reviewer and mentor at the PKC Corporation, a Burlington company that develops software for linking patient information with medical literature. A memorial service for Dr. Tisdale will be held on campus on April 26. W I N T E R / S P R I N G 2007 39 P r o f i l e s in g i v i n g A Family Presence for three generations & beyond november 15, 2006 5:50 p.m. mimi reardon classroom For the Bove family of Rutland, Vt., connections to the generous commitment has been recognized with the nam- College of Medicine run long and deep. Ernest Bove, M.D., ing of a room in the Student Assessment Center. Exam (at right) is a member of the Class of 1981 and a urologist in Room 12 will now be known as the Bove Family Room. Rutland. His father, Edward, was a 1946 graduate of the Naming opportunities can create a visible legacy of your College. Today, a third generation of the Bove family, Erica, connection to the College of Medicine. They exist at many (at left) is learning the art and science of medicine at the varying levels, from laptop computers and student lockers school as a member of the Class of 2009. to conference rooms and larger teaching facilities. For more The Bove family has long recognized the important place the College holds in their family history with sustained sup- Kelly Mebust, class of 2010, works on her needle skills during a suturing workshop for first- and second- year medical students. information, please contact the Development and Alumni Relations Office. port of the College’s fundraising efforts. Their most recent photograph by Raj Chawla medical development and alumni relations office (802)656-4014 [email protected] www.med.uvm.edu/giving 40 V E R M O N T M E D I C I N E W I N T E R / S P R I N G 2007 41 Crafting the future Albert D. Blenderman, M.D.’43 spent decades repairing and reshaping the human body as an orthopaedic surgeon. In retirement, his trained hands have continued to craft the subtle forms of bone and flesh — in the meticulous carvings of birds he brings to life from blocks of wood. Dr. Blenderman and his wife, Virginia, have also helped to shape the future of medical care, with their generous establishment of the Albert D. Blenderman, M.D.’43 Endowed Scholarship Fund. For more than six years, medical and nursing students have benefited from the support the Blenderman Scholarship Fund has provided. One current medical student recently expressed to Dr. Blenderman the significance of scholarship support in her life: JEFF FAY “This is a note of tremendous gratitude for such an outstanding financial gift! As I begin this lifelong endeavor of learning and practice in medicine, I am inspired by the fulfilling environment UVM has created for medical students, and how supportive its alumni are. You are an example for me, and I thank you for that.” For more information on scholarship support, contact: university of vermont college of medicine medical development and alumni relations office (802) 656-4014 [email protected] www.med.uvm.edu/giving VERMONT MEDICINE 89 Beaumont Ave. Burlington, Vermont 05405 Your gift to the College of Medicine can, as the Blendermans’ has, shape medical careers in a positive way for decades to come. Donors have two new options for creating a named scholarship at the UVM College of Medicine — a currently funded scholarship or an endowed scholarship. Each of these opportunities can leverage matching dollars generously provided by the Medical Alumni Association. Non-Profit Org. U.S. POSTAGE PAID Burlington, VT Permit No. 143