Transdisciplinary Teams Launch

The eALERT is an internal newsletter sent semi-monthly.
Please send submissions for the eALERT to Sarah Keblin by 4 PM Wednesday for
submission in the current issue.
Thursday, January 21, 2016
TDT Leadership Kick-Off
Transdisciplinary Teams Launch
Juckett Lecture to feature
Dinah Singer, PhD
FINAL REMINDER: ACS IRG
Funding Call for Applications
Red Sox Foundation--Your
Votes Needed!
UVM Athletics' Rally Against
Cancer Tickets Available
UVM Cancer Center in the
NEWS
Publications and
Announcements
Funding Opportunities- NEW
LISTINGS THIS WEEK
Ongoing Events
TDT leaders gather for strategic planning session
On Tuesday, January 19th, representative leaders of the
newly formed Transdisciplinary Teams (TDTs), came
together for the official kick-off to implement TDT purpose
and build the infrastructure to fulfill the mission of the
UVM Cancer Center. The teams are comprised of clinical
providers across disciplines involved in the care of patient
groups, coupled with interested translational and basic
scientists and designated research coordinators or nurses.
Each TDT is charged with formalizing a clinical research
strategy based on local expertise and unmet needs for a
disease site. They will work collaboratively with the UVM
Cancer Center Scientific Programs, to help bring discovery
to the improvement of patient care.
The current meeting schedule for active TDT teams is
below:
Event Spotlight
January 22
Biochemistry Seminar
Series
"Genetic Analysis of
Ikaros tumor
suppressor function in
BCRABL1 pre-B ALL"
Breast Oncology TDT: second Monday of the Month,8- 9
AM, College of Medicine, MedEd 205. Contact:
[email protected]
Lung Oncology TDT: Last Tuesday of the month, 12:30 1:30 pm, ACC third floor Dermatology conference room.
Next Meeting on Dec. 22. Contact:
[email protected]
Gastrointestinal Oncology TDT: third Monday of the
month, 7:30-8:30 am, Radiation Oncology Conference
room. Contact: [email protected]
Hematologic Oncology TDT: first Friday of the month, 121 pm, ACC third floor Dermatology conference room.
Contact: [email protected]
by Seth Frietze, PhD
Given C443
12 Noon
Juckett Lecture to Feature
Dinah Singer, PhD
SAVE THE DATE
Events Calendar
January 2016
National Cervical Health
Awareness Month
22 Biochemistry Seminar
Series: "Genetic Analysis of
Ikaros tumor suppressor
function in BCRABL1 pre-B ALL,"
by Seth Frietze, PhD; Given
C443, 12 PM.
22 Pink Powder Day at
Bolton Valley to benefit
Komen VT/NH
25 SPARK-VT Workshop:
"Accessing America's Largest
Seed Fund: SBIR in Depth,"
featuring Jake Reder, PhD, CEO,
Celdara Medical, LLC; Chittenden
Bank Room, Dudley Davis Center
(Room 413).
Dinah Singer, PhD, head of
the Molecular
Regulation Section and
Director of the Division of
Cancer Biology at the
National Cancer Institute,
will present a J. Walter
Juckett Distinguished
Lecture on March 3, 2016 at
12 PM in Davis Auditorium.
Dr. Singer's lab is focused
Dinah Singer, PhD
on the long-term goal of
defining the molecular mechanisms regulating gene
expression. Her presentation will be: "Linking
Transcription and Chromatin Structure: The
Bromodomain Protein, BRD4."
Lunch will be available for attendees.
FINAL REMINDER: ACS IRG
Applications Due Feb. 1
A third call for applications for funding through the
American Cancer Society Institutional Research Grant,
awarded earlier this year to the UVM Cancer Center, is
underway.
Grant applications are invited from junior faculty for
award of a research grant of up to $30,000 for one year.
February 2016
National Cancer Prevention Month
5 UVM Athletics' Rally Against
Cancer Men's
Hockey vs. Notre Dame,
7:05 PM.
14 UVM Athletics' Rally Against
Cancer Men's Basketball vs.
Hartford, 2 PM; please contact
Charles Brooks for tickets (limited
tickets available for UVM Cancer
Center members and staff.).
20 UVM Athletics' Rally Against
Cancer Women's Basketball vs.
UMBC, 2 PM; please contact Charles
Brooks for tickets (limited tickets
available for UVM Cancer Center
members and staff).
Funded research will cover the cancer continuum and
emphasize transdisciplinary, translational investigation via
the UVM Cancer Center's three research programs:
Molecular Mechanisms of Malignancy, Host Factors and
Tumor Progression, and Cancer Control and Population
Health Sciences. The research must involve a
collaboration between a laboratory or behavioral scientist
and a physician investigator. Investigators associated with
the University of Vermont and the Albany College of
Pharmacy and Health Sciences Vermont campus are
eligible to apply.
ACS-IRG grants are intended for new investigators (within
six years of first independent academic appointment) who
do not have an active, nationally competitive research
grant (e.g., NIH, NSF, ACS).
Deadline for Submission is February 1, 2016
ACS-IRG Guidelines and Applications may be found at
the UVM Cancer Center Website.
Please contact Ed North at (802) 656-9450 or
[email protected] with any questions.
March 2016
Red Sox Fans--VOTE
UVM Cancer Center!!
3 J. Walter Juckett Distinguished
Lecture, "Linking Transcription and
Chromatin Structure: The
Bromodomain Protein,
BRD4," featuring Dinah Singer, PhD,
Director of the NCI Division of Cancer
Biology; Davis Auditorium, 12 noon.
The Boston Red Sox Foundation is promoting the IMPACT
Awards program, which provides Red Sox fans in
surrounding New England states with the opportunity to
support a local non-profit by casting their votes. Please
consider joining us in building support for the UVM Cancer
Center through this fun program. We will not only be in
the running for a grant--but, it would be a great
opportunity to build awareness regionally for the amazing
work being done in cancer research, education and
patient care, here in Vermont!
Colorectal Cancer Awereness Month
National Nutrition Month
April 2016
National Cancer Control Month
29 **SAVE THE DATE**: UVM
Cancer Center Clinical and
Translational Research
Symposium: "Hemostasis,
Thrombosis and Cancer".
29-1 Stowe Weekend of
Fans must register on the Boston Red Sox fan page in
order to vote. To vote for the UVM Cancer Center, or for
more information, visit the IMPACT Awards webpage.
Please share with friends and family!
Hope
UVM Athletics' Rally Against Cancer
May 2016
Skin Cancer Detection and
Prevention Month and Cancer
Research Month
9 UVM Cancer Center hosts
Northeast Genomic
Instability Meeting. More info.
to come!
June 2016
National Cancer Survivors Month
National Men's Health Week
UVM Athletics will once again host the annual Rally
Against Cancer games, including Men's and Women's
Hockey and Basketball. The games, presented by sponsor
Otter Creek Awnings and Vermont Custom Closets, are
aimed at building awareness and support for cancer
research happening here at UVM. This year, in partnership
with UVM Athletics, survivors will play a more active role
in games as well.
UVM Cancer Center members interested in receiving
complimentary tickets should contact Charles Brooks.
Tickets are still available for Women's Basketball on a
first-come, first-served basis.
For more information about game dates and times please
check the UVM Cancer Center website.
24 UVM Cancer Center's
Men's Health and Cancer
Conference - SAVE THE DATE!
October 2016
National Cancer Survivors Month
National Men's Health Week
7 UVM Cancer Center's
Women's Health and Cancer
Conference (formerly Breast
Cancer Conference)--SAVE
THE DATE!!!
Claire Verschraegen, MD and Gary Stein, PhD join athletes and Todd
Warren of Otter Creek Awnings and Vermont Custom Closets on ice
UVM Cancer Center
in the NEWS
Emily Harwood, UVM Cancer Center
compliance specialist, has been
honored by WPTZ TV as a Hometown
Hero for her dedicated work as a
volunteer mentor for the Howard
Center. Emily has mentored the same
individual for more than five years
now! Click here to see the segment.
Emily Harwood
Publications and
Announcements
*Please send announcements and publication notices to
Sarah Keblin for inclusion in the eALERT and other
promotional material*
Publications:
Histone H3 lysine 4 acetylation and methylation dynamics
define breast cancer subtypes. Messier TL, Gordon JA,
Boyd JR, Tye CE, Browne G, Stein JL, Lian JB, Stein
GS. Oncotarget. 2016 Jan 15. doi:
10.18632/oncotarget.6922. [Epub ahead of print] PMID:
26783963.
Statin Use and Breast Cancer Risk in the Nurses' Health
Study. Borgquist S, Tamimi RM, Chen WY, Garber JE,
Eliassen AH, Ahern TP. Cancer Epidemiol Biomarkers
Prev. 2016 Jan;25(1):201-6. doi: 10.1158/10559965.EPI-15-0654. PMID: 26762806.
Expression of Ribosomal RNA and Protein Genes in Human
Embryonic Stem Cells Is Associated with the Activating
H3K4me3 Histone Mark.Zaidi SK, Boyd JR, Grandy R,
Medina R, Lian JB, Stein GS, Stein JL. J Cell Physiol.
2016 Jan 11. doi: 10.1002/jcp.25309. [Epub ahead of
print] PMID: 26755341.
MicroRNA-378-mediated suppression of Runx1 alleviates
the aggressive phenotype of triple-negative MDA-MB-231
human breast cancer cells. Browne G, Dragon JA, Hong
D, Messier TL, Gordon JA, Farina NH, Boyd JR,
VanOudenhove JJ, Perez AW, Zaidi SK, Stein JL, Stein
GS, Lian JB. Tumour Biol. 2016 Jan 9. [Epub ahead of
print] PMID: 26749280.
Arf6 controls platelet spreading and clot retraction via
integrin αIIbβ3 trafficking. Huang Y, Joshi S, Xiang B,
Kanaho Y, Li Z, Bouchard BA, Moncman CL, Whiteheart
SW. Blood. 2016 Jan 6. pii: blood-2015-05-648550. [Epub
ahead of print ] PMID: 26738539.
Clinical features of venous insufficiency and the risk of
venous thrombosis in older people. Engbers MJ, Karasu A,
Blom JW, Cushman M, Rosendaal FR, van Hylckama
Vlieg A. Br J Haematol. 2015 Nov;171(3):417-23. doi:
10.1111/bjh.13579. Epub 2015 Jul 27. PMID: 26221838.
C-ing the Genome: A Compendium of Chromosome
Conformation Capture Methods to Study Higher-Order
Chromatin Organization. Barutcu AR, Fritz AJ, Zaidi SK,
van Wijnen AJ, Lian JB, Stein JL, Nickerson JA,
Imbalzano AN, Stein GS. J Cell Physiol. 2016
Jan;231(1):31-5. doi: 10.1002/jcp.25062. Review. PMID:
26059817.
Mechanisms and Consequences of Double-Strand DNA
Break Formation in Chromatin. Cannan WJ, Pederson
DS. J Cell Physiol. 2016 Jan;231(1):3-14. doi:
10.1002/jcp.25048. Review. PMID: 26040249.
Funding Opportunities
Green indicates NEW
An extensive list of upcoming, extramural funding
opportunities can now be found on the UVM Cancer
Center website. This list will be updated monthly,
however highlighted opportunities from this larger
list will still appear in the eALERT. Please send
funding opportunities you'd like to add to the list
to Ed North.
Some upcoming funding opportunity highlights:
•
•
UVM Industry Fellowship Program; seeks to
address needs of businesses by partnering them
with the expertise of UVM faculty membersand
graduate students or postdoctoral research
associates; faculty will identify industry/project;
contact Dan Harvey in the OVPR for more
information.
ACS Research Professor Grants; for mid-career
investigators who have made seminal contributions
that have impacted direction of basic science
•
•
•
•
•
•
•
•
research ($80,000/year for salary or research
support); letter of intent due Feb. 1, 2016 (full
applications due April 1).
L'Oreal USA For Women in Science Fellowship
Program grants; $60,000 for postdoctoral
females in any specialty; deadline is Feb. 5, 2016.
UVM Cancer Center ACS IRG Call for Applications;
internal call, deadline for submission is
February 1, 2015.
National Academies of Sciences, Engineering and
Medicine NRC Research Associateship Programs;
varying 2016 deadlines (Feb. 1, May 1 August
1, and November 1).
American Cancer Society Graduate Scholarships in
Cancer Nursing Practice; deadline for submission is
February 1, 2015.
Nano Startup Challenge in Cancer: Driving
Innovation in Cancer Nanomedicine; rolling
enrollment in the competition through
February 11, 2016.
UVM SPARK Program Call for pilot projects with an
objective of translating innovative discoveries into
the marketplace. Emphasis will be placed on
technologies that have the potential to advance
rapidly into a commercialization pathway.
Completed proposals must be received by
midnight, February 12, 2016.
Charles H. Hood Foundation Child Health
Research Awards Program; upt to $150,000 for
2 years; deadline is March 21, 2016, noon EST.
Bayer Grants for Targets ; encouraging innovation
and translation of ideas from basic research into
novel drugs; deadline is March 31, 2016.
UVM Cancer Center Research Grants
A full list of all organizations designated by the NCI
as providing peer-reviewed funding can be found
here.
Ongoing Events
Cancer Biology and Technology Seminar Series (an
integrated part of the Biochemistry Seminar Series)
Second Friday of each month at Noon, Given C443.
UVM Cancer Center Grand Rounds
1st, 2nd, 3rd, 5th
Tuesday 8-9am, MedEd 300
Please refer to the UVM Cancer Center Website for
information regarding regularly scheduled tumor board
meetings. Information can be found here.
UVM Cancer Center Leadership:
Gary S. Stein, PhD, Director
Claire F. Verschraegen, MD, Deputy Director, Cancer Service Line Director
Kate Webster, CRA, Research Center Administrator
Sarah Keblin, Communications Manager