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Face-to-Face - Fondazione ICONA
SCIENTIFIC PROGRAMME Face-to-Face HIV and COINFECTIONS 2nd INTERCOHORTS MEETING Scientific Coordinators Andrea Antinori Antonella Castagna Francesca Ceccherini-Silberstein ROME January 29-30, 2016 Auditorium Via Veneto Alessandro Cozzi-Lepri Antonella d’Arminio Monforte Enrico Girardi Sergio Lo Caputo Italian Cohort Cristina Mussini I. Massimo Puoti C N O. A. Naive Antiretrovirals Fondazione Icona ITALIAN COHORT NAIVE ANTIRETROVIRALS Founded by Professor Mauro Moroni ICONA FOUNDATION STUDY GROUP Board of Directors A. d’Arminio Monforte (Vice-President), M. Andreoni, G. Angarano, A. Antinori, F. Castelli, R. Cauda, G. Di Perri, M. Galli, R. Iardino, G. Ippolito, A. Lazzarin, C.F. Perno, F. von Schlösser, P. Viale Presidential Commitee A. Antinori, A. d’Arminio Monforte, G. Ippolito, A. Lazzarin, C.F. Perno F A C U LT Y Scientific Secretary A. Antinori, A. Castagna, F. Ceccherini-Silberstein, A. Cozzi-Lepri, A. d’Arminio Monforte, E. Girardi, S. Lo Caputo, C. Mussini, M. Puoti Steering Committee A. Ammassari, M. Andreoni, A. Antinori, C. Balotta, A. Bandera, P. Bonfanti, S. Bonora, M. Borderi, A. Calcagno, L. Calza, M.R. Capobianchi, A. Castagna, F. Ceccherini-Silberstein, A. Cingolani, P. Cinque, A. Cozzi-Lepri, A. d’Arminio Monforte, A. De Luca, A. Di Biagio, N. Gianotti, E. Girardi, A. Gori, G. Guaraldi, G. Lapadula, M. Lichtner, S. Lo Caputo, G. Madeddu, F. Maggiolo, G. Marchetti, S. Marcotullio, L. Monno, C. Mussini, S. Nozza, M. Puoti, E. Quiros Roldan, R. Rossotti, S. Rusconi, M. Santoro, A. Saracino, M. Zaccarelli Statistical and Monitoring Team A. Cozzi-Lepri, I. Fanti, L. Galli, P. Lorenzini, A. Rodano, M. Shanyinde, A. Tavelli Biological Bank INMI F. Carletti, S. Carrara, A. Castrogiovanni, A. Di Caro, F. Petrone, G. Prota, S. Quartui ROME January 29-30, 2016 Auditorium Via Veneto Face-to-Face HIV and COINFECTIONS Promoted by the ICONA Foundation Study, the Face-to-Face 2nd Intercohorts Meeting is a closed-workshop dedicated to ICONA researchers which also involve representatives of some of the major European Cohorts enrolling patients with HIV and coinfections (CRNS, France EuroSIDA, Denmark - GeSIDA, Spain - ICONA, Italy - HepaICONA, Italy - Swiss Cohort, Switzerland - Piter, Italy). The aim of the workshop is pursuing new findings, analyses as well as works in progress and allows open discussions among European Experts on cutting-edge issues in HIV and coinfections. For this reason, the scientific program of this two-day Meeting has been structured into two sections: Day one, January 29 Based on five themes, interactive round tables among cohorts representatives on the following main topics: Long-term outcomes in the treatment of HIV Future settings of HIV/HCV coinfection Long-term outcomes in the treatment of HCV New perspectives in hepatitis B and Delta Scientific evidence and new research project by ICONA and HepaICONA Cohort in the treatment of HIV and HIV/HCV coinfection Day two, January 30 Based on ICONA Foundation latest data and scientific projects discussion among all researchers from ICONA clinical sites only. SCIENTIFIC R AT I O N A L E 2nd INTERCOHORTS MEETING ADRIANA AMMASSARI IRCCS – INMI Lazzaro Spallanzani, Rome I MASSIMO ANDREONI University of Tor Vergata, Rome I GIOACCHINO ANGARANO University Hospital of Bari I ANDREA ANTINORI IRCCS - INMI Lazzaro Spallanzani, Rome I JUAN BERENGUER Gregorio Marañón University Hospital, Madrid E F A C U LT Y RAFFAELE BRUNO University of Pavia I STEFANIA CARRARA IRCCS – INMI Lazzaro Spallanzani, Rome I ANTONELLA CASTAGNA San Raffaele Scientific Institute, Milan I ROBERTO CAUDA Catholic University, Rome I FRANCESCA CECCHERINI-SILBERSTEIN University of Tor Vergata, Rome I ANTONIO CHIRIANNI Domenico Cotugno Hospital, Naples I ANTONELLA CINGOLANI Catholic University, Rome I ALESSANDRO COZZI-LEPRI Royal Free & University College Medical School - University College of London UK ANTONELLA D’ARMINIO MONFORTE San Paolo Hospital, University of Milan I GIOVANNI DI PERRI University of Turin I IURI FANTI Catholic University, Rome I GIOVANNI BATTISTA GAETA Second University of Naples I ROME January 29-30, 2016 Auditorium Via Veneto Face-to-Face HIV and COINFECTIONS 2nd INTERCOHORTS MEETING MASSIMO GALLI Luigi Sacco Hospital, University of Milan I ENRICO GIRARDI IRCCS - INMI Lazzaro Spallanzani, Rome I GIUSEPPE IPPOLITO IRCCS - INMI Lazzaro Spallanzani, Rome I LORETA KONDILI Istituto Superiore di Sanità, Rome I HELEN KOVARI University Hospital, Zurich CH MIRIAM LICHTNER Sapienza University of Rome, Polo Pontino, Latina I SERGIO LO CAPUTO University Hospital of Bari I GIULIA MARCHETTI San Paolo Hospital, University of Milan I CRISTINA MUSSINI University Hospital of Modena and Reggio Emilia, Modena I CARLO FEDERICO PERNO University of Tor Vergata, Rome I LARS PETERS University of Copenhagen DK MASSIMO PUOTI Niguarda Ca’ Granda Hospital, Milan I DOMINIQUE SALMON Cochin Hospital, Rene Descartes University, Paris F ANNALISA SARACINO University Hospital of Bari I MILENSU SHANYINDE Royal Free & University College Medical School - University College of London UK GLORIA TALIANI Sapienza University, Rome I ALESSANDRO TAVELLI San Paolo Hospital, University of Milan I F A C U LT Y ADRIANO LAZZARIN University Vita-Salute San Raffaele, Milan I FRIDAY JANUARY 29, 2016 10.00-11.15 Registration 11.15-11.30 Introduction: rationale and aims of the 2nd Icona Intercohorts Meeting A. Antinori, A. d’Arminio Monforte, M. Puoti PROGRAMME 11.30-11.45 The role of Italian infectious diseases specialists in the International setting A. Chirianni 11.45-13.45 Interactive Round Table among European Cohorts Insights HIV/HCV coinfection: future scenarios, what Cohorts are doing, what we can do together Chairs: A. Antinori, A. d’Arminio Monforte, M. Puoti Participants: Dominique Salmon CRNS France Lars Peters EuroSIDA Denmark Juan Berenguer GeSIDA Spain Helen Kovari Swiss Cohort Switzerland Loreta Kondili Piter Italy Antonella d’Arminio Monforte ICONA and HepaICONA Cohorts Italy 13.45-14.30 Lunch ROME January 29-30, 2016 Auditorium Via Veneto Face-to-Face HIV and COINFECTIONS 2nd INTERCOHORTS MEETING 14.30-15.50 Meet the Experts Chairs: G. Di Perri, G. Taliani 14.30-14.50 Lecture C. Mussini 14.50-15.10 Lecture Long term outcome in HIV treatment M. Andreoni 15.10-15.30 Lecture Long term outcome in HCV treatment M. Puoti 15.30-15.50 Lecture New perspectives in hepatitis B and Delta treatment G.B. Gaeta 15.50-16.10 Discussion 16.10-16.30 Coffee break PROGRAMME Retention in care: role of cohort studies FRIDAY JANUARY 29, 2016 16.30-17.20 SESSION 1 ICONA research in HIV and HIV-HCV coinfection Chairs: R. Cauda, A. Lazzarin 16.30-16.40 Challenges of anti HCV treatment in persons living with HIV in the era of Directly Acting Antivirals (DAA) M. Puoti PROGRAMME 16.40-16.50 PrecART proinflammatory milieu, microbial translocation (MT) and risk of disease progression in HIV Infected patients starting their first cART G. Marchetti 16.50-17.00 Risk and determinants of failure of a monoPI/r simplification strategy with LPV/r or DRV/r in clinical practice M. Andreoni 17.00-17.10 HIV-positive subjects treated with EVG/COBI based regimens - preliminary data A. Cozzi-Lepri 17.10-17.20 CD4 explosion after effective HAART in HIV people: the hidden meaning M. Lichtner 17.20-17.40 Discussion ROME January 29-30, 2016 Auditorium Via Veneto Face-to-Face HIV and COINFECTIONS 2nd INTERCOHORTS MEETING 17.40-18.30 SESSION 2 ICONA research in HIV and HIV-HCV coinfection 17.40-17.50 Survival in HIV-1 positive and HIV negative individuals with diagnosis of lymphoma A. Cingolani 17.50-18.00 Increased risk of virological failure to the first antiretroviral regimen in HIV-infected migrants compared to natives A. Saracino 18.00-18.10 Correlations of pre-ART HIV-DNA with outcome in 1st-line treated ART patients F. Ceccherini-Silberstein 18.10-18.20 Determinants and impact of late HCV diagnosis among persons with newly diagnosed HIV infection M. Shanyinde 18.20-18.30 Low-level viremia (LLV) ranging from 50 to 500 copies/mL is associated to an increased risk of AIDS events A. Antinori 18.30-18.50 Discussion 18.50-19.00 Final conclusions A. Antinori, A. d’Arminio Monforte, M. Puoti PROGRAMME Chairs: G. Angarano, C.F. Perno SATURDAY JANUARY 30, 2016 SESSIONE 3 Moderatori: R. Bruno, M. Galli, G. Ippolito 09.00-09.20 Il valore di ICONA nello scenario internazionale A. Castagna PROGRAMME 09.20-10.20 10.20-11.20 Presentazione del report ICONA ed HepaICONA ICONA S. Lo Caputo HepaICONA A. Ammassari Questionario ICONA-PRO A. Cingolani, E. Girardi 11.20-11.50 Coffee break 11.50-13.30 Spazio di discussione con i Centri Conducono: S. Carrara, I. Fanti, A. Tavelli 13.30-13.45 Considerazioni conclusive e chiusura dei lavori A. Antinori, A. d’Arminio Monforte, M. Puoti ROME January 29-30, 2016 Auditorium Via Veneto Face-to-Face HIV and COINFECTIONS Venue Auditorium Via Veneto Via Veneto, 89 - 00187 Rome I www.auditoriumviaveneto.it Crediti ECM La Commissione Nazionale per la Formazione Continua in Medicina ha assegnato n. 11 crediti formativi al Meeting (N. ECM 150-143229), per Biologi, Farmacisti ospedalieri e territoriali e Medici Specialisti in Malattie Infettive, Microbiologia e Virologia, Igiene, Epidemiologia e Sanità Pubblica, Direzione Medica di Presidio Ospedaliero, Allergologia e Immunologia Clinica, Medicina Interna e Gastroenterologia. L’assegnazione dei crediti formativi è subordinata alla presenza al 100% dei lavori e alla corretta compilazione di almeno il 75% delle domande proposte all’interno del questionario di valutazione finale. È inoltre obbligatoria la rilevazione delle presenze e la compilazione del questionario di valutazione e di gradimento dell’evento formativo. CME Provider and Organizing Secretariat Effetti Srl Via Gallarate, 106 - 20151 Milan, Italy Ref. Barbara Bocciardi Phone +39 02 3343281 - Fax +39 02 38002105 Mail: [email protected] www.effetti.it - www.fondazioneicona.org GENERAL I N F O R M AT I O N 2nd INTERCOHORTS MEETING The Scientific Coordinators, the Scientific Secretariat and the Provider wish to thank the following Companies for support given in the form of unrestricted educational grants: THANKS TO THE SPONSORS PLATINUM SPONSORS GOLD SPONSORS OTHER SPONSOR ROME January 29-30, 2016 Auditorium Via Veneto