Rosalinda Madonna, MD, PhD CURRICULUM VITAE

Rosalinda Madonna, MD, PhD
CURRICULUM VITAE
Indirizzo di residenza:
Via Armellini, 18 66100 Chieti, Italy
Indirizzo professionale:
Istituto di Cardiologia, Università degli Studi “G. d’Annunzio” – Chieti, c/o Ospedale S. Camillo
de Lellis, Via Forlanini 50, 66100 Chieti, Italy Tel: 0871-41512; Fax: 0871-41512
Educazione:
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Laurea in Medicina e Chirurgia, Università degli Studi “G. d’Annunzio”, Chieti (1990-marzo 1997)
Curriculum degli studi: voto di Laurea 110/110 e lode, 56 esami sostenuti secondo Tabella XVIII della riforma degli Studi di
Medicina, media dei voti riportati: 29,7
Discussione della Tesi di Laurea Sperimentale: " Hind III lipoproteinlipase polimorfism and coronary artery disease”,
Relatore Prof. A. Barsotti, Controrelatore Prof. A. Procopio.
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Esame di Stato per l’Iscrizione all’Albo Professionale medico di Chieti Medical Board of Chieti, Italy (settembre 1997)
Università degli Studi “G. d’Annunzio”, Chieti, Dottorato di Ricerca in Tecnologie Biomediche e Bioimmagini Funzionali ad
indirizzo cardiologico, XV CICLO, 1998-2002
Mentore scientifico per la formazione alla Ricerca Prof. Raffaele De Caterina
Febbraio 2003: discussione della tesi di dottorato: “Regolazione dell’espressione citochino-indotta del gene ossido nitrico
sintetasi inducibile in cardiomioblasti”.
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Università degli Studi “G. d’Annunzio”, Chieti , Classe 1999-2003, classificata prima all’esame di ammissione alla Scuola di
Specializzazione in Cardiologia, Direttore: Prof. A. Barsotti, interrotta per il completamento degli studi di Dottorato di
Ricerca
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Texas University Health Science at Houston, TX (Settembre 2002 –Settembre 2004)
Post-doctoral Research Fellow, presso il Center for Cardiovascular Biology and Atherosclerosis Research, Mentore Prof.
Yong-Jian Geng
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Texas Heart Institute at St. Luke’s Hospital, Houston TX (Settembre 2002 –Settembre 2004 )
Post-doctoral Research Fellow, presso Stem Cell and Heart Failure Laboratory, Mentore Prof. Yong-Jian Geng
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Università degli Studi “G. d’Annunzio”, Chieti, Classe 2003-2007, classificata prima all’esame di ammissione alla Scuola di
Specializzazione in Cardiologia, Direttore: Prof. R. De Caterina
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Iscritta al secondo anno della Facoltà di Scienze Biologiche, Università degli Studi dell’Aquila.
Esperienze in ambito universitario, lavorativo e corsi di formazione:
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Istitutional animal training course (marzo 2003), presso la University of Texas-Houston Health Science Center, TX
Istitutional hazardous chemical safety training course (settembre 2003), presso la University of Texas-Houston Health
Science Center, TX
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Istitutional radioactive safety training course (gennaio 2004), presso la presso la University of Texas-Houston Health
Science Center, TX
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University of Texas Medical School at Houston, Texas (2003)
Ha seguito 1 studente di Medicina per il programma di “summer research” in tema di Cellule Staminali applicate alla biologia
cardiovascolare.
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Università degli Studi “G. d’Annunzio”, Chieti (2000)
Ha preso parte come istruttore a lezioni di Semeiotica Medica cardiovascolare per studenti di medicina, presso il reparto di
Cardiologia, Ospedale S. Camillo de Lellis, Chieti
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Università degli Studi “G. d’Annunzio”, Chieti (2000)
Ha seguito 2 studenti di Medicina nella preparazione della tesi di Laurea in tema di Aterosclerosi e Diabete
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Servizio di Guardia Medica estiva ed invernale presso la ASL Lanciano-Vasto (giugno-agosto 1998; giugno-agosto 1999;
giugno-agosto 2000; giugno-agosto 2001; impegno non continuativo nei mesi invernali degli anni 2001 e 2002)
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Università degli Studi “G. d’Annunzio”, Chieti (1996 - 1998)
Studente interno, Istituto di Scienze Cardiovascolari, Dir. Prof. A. Barsotti
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Università degli Studi “G. d’Annunzio”, Chieti (1997 - 1998)
Corso annuale di Perfezionamento in Ecografia Interna, Dir. Prof. Marzio
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Università degli Studi “G. d’Annunzio”, Chieti (1996-1998)
Tirocinio volontario di Ricerca presso i Laboratori di Farmacologia (Dir. Prof. Caciagli), Genetica Medica (Dir. Prof. Palka) e
Patologia Generale ( Dir. Prof. A. Procopio)
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Università degli Studi dell’Aquila (1993-1995)
Studente Interno, Reparto di Medicina Interna, Dir. Prof. A. Santucci
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Università degli Studi dell’Aquila (1992-1993)
Tirocinio obbligatorio presso il Laboratorio di Patologia Generale, Dir. Prof. Gulino
Membro di Società Scientifiche:
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Membro ordinario della Società Italiana di Cardiologia (2001-presente)
Membro ordinario della Società Italiana di Trombosi ed Emostasi (2002- presente)
Membro ordinario della European Association Study of Diabetes (EASD, 2004 - presente )
Premi di Ricerca e Fellowship:
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2002: Young Investigator Award, Società Italiana Studio Trombosi ed Emostasi (SISET)
2003: Young Investigator Award, International Society of Thrombosis and Haemostasis
2002-2004: Post-doctoral Research Fellowship, University of Texas Medical School, Houston TX
2004: Travel Grant Award for Young Scientists, “1st Workshop on Adipose Tissue-derived Stem Cells”, Tulane University
Health Science Center, New Orleans LA, USA june 5-6 2004
2004: Young Investigator Award, European Association Study of Diabetes (EASD)
2004: Young Investigator Award, Società Italiana Studio Trombosi ed Emostasi (SISET)
Supporti per la Ricerca:
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NHI/NHLB1
P.I.: Prof. Geng, Yong-Jian
2002-2004
“Human embryonic stem cell growth and apoptosis in high density cultures”
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Fondi per la Ricerca, Centro Scienze dell’Invecchiamento (CESI) e Consorzio Italiano Ricerche Cardiovascolari (C.I.R.C.),
P.I.: Prof. Raffaele De Caterina
2000-2002
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Fondi per la Ricerca, Centro Scienze dell’Invecchiamento (CESI) e Consorzio Italiano Ricerche Cardiovascolari (C.I.R.C.),
P.I.: Prof. Raffaele De Caterina
2004-
Relazioni ad invito:
1.
January 2003, Seminar Series of Vascular Biology, University of Texas Medical School at Houston: Inhibition of 3hydroxy-3-methylglutaryl coenzyme A reductase attenuates expression of inducible nitric oxide synthase in cardiac
myoblasts. Possible link to direct myocardial protection during ischemia-reperfusion.
2. January 2004, Seminar Series of Vascular Biology, University of Texas Medical School at Houston: Adipose tissue
derived stem cells: new concepts in cardiovascular cell therapy.
3.
November 2004, Seminar Series del Centro Scienze dell’Invecchiamento, CESI presso
l’Università degli Studi di
Chieti, Italy: “Cellule staminali adulte derivate da tessuto adiposo per la rigenerazione cardiaca: caratterizzazione,
meccanismi, dati animali e potenzialità”.
Partecipazione a conferenze nazionali ed internazionali come “presenting author” di contributi scientifici:
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M Soccio, R Madonna, A Taccardi, A De Finis, G D’Apolito, F Romanazzi, D Statile, P Di Napoli, S Gallina, A Barsotti .
Polimorfismo del gene di conversione dell’angiotensina ed aterosclerosi carotidea nella popolazione con coronaropatia
severa e popolazione di controllo. 59° Congresso Nazionale della Società Italiana di Cardiologia, Roma, Italy 12-16
december 1998. Oral communication.
R Madonna, M Soccio, G D’Apolito, P Perfetti, P Tiloca, M Zimarino, S Gallina, A Barsotti. Relazione fra malattia
coronarica ed aterosclerosi aortica e carotidea. Fattori di rischio comuni?. 60° Congresso Nazionale della Società
Italiana di Cardiologia, 11-15 december 1999 Roma Italy. Oral commnication
R Madonna, A Pandolfi, M Massaro, A Consoli, R De Caterina: Insulin enhances vascular cell adhesion molecule (VCAM-1)
expression in human cultured endothelial cells. A link to the pathogenesis of accelerated atherosclerosis in diabetes.
XIX Congress of the International Society on Thrombosis and Haemostasis, Birmingham UK 12-18 July 2003. Oral
communication, Young Investigator Award.
R Madonna, P Di Napoli, A Grilli, M Felaco, Y-J Geng, R De Caterina: Inhibition of 3-hydroxy-3-methylglutaryl
coenzyme A reductase attenuates expression of inducible nitric oxide synthase in cardiac myoblasts. Possible link to
direct myocardial protection during ischemia-reperfusion.
2003 Research Day, The graduate and postgraduate research forum, Excellence in Biomedical Research, 9th Annual
Event November 14 2003, poster
Madonna R, Li S, Lin J, Rajabi M, Wassler M J, Geng Y-J: Characterization and heart transfusion of stromal cell
progenitors isolated from adipose tissue
2003 Research Day, The graduate and postgraduate research forum, Excellence in Biomedical Research, 9th Annual
Event November 14 2003, Houston TX oral presentation, abstract selected among first 6 finalist abstracts for
awarding.
R Madonna, P Di Napoli, A Grilli, M Felaco, Y-J Geng, R De Caterina: Inhibition of 3-hydroxy-3-methylglutaryl
coenzyme A reductase attenuates expression of inducible nitric oxide synthase in cardiac myoblasts. Possible link to
direct myocardial protection during ischemia-reperfusion.
Journal of American College of Cardiology 2004, march 3 vol. 43 suppl A 1116-34
53rd Annual Scientific Session, New Orleans La, USA march 7-10 2004, featured poster with presentation
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R Madonna, Li S, Lin J, Rajabi M, Wassler M J, Geng Y-J: Characterization and heart transfusion of stromal cell
progenitors isolated from adipose tissue. “1st Workshop on Adipose Tissue-derived Stem Cells”, Tulane University
Health Science Center, New Orleans LA, USA june 5-6 2004
R Madonna, R De Caterina, J T Willerson, YJ Geng: Adult Mesenchymal Stem Cells Derived from Adipose Tissue Highly
Express Telomerase and Spontaneously Differentiate into Contractile Cardiomyocytes and Mature endothelial cells.
Diabetologia suppl. September 2004; International Congress of European Association Study of Diabetes (EASD),
Munich 5-7 September 2004, Oral communication
R Madonna, Li S, Lin J, Rajabi M, Wassler M J, R De Caterina, Geng Y-J: Characterization and Heart Trasfusion of
Endothelial Progenitor Cells isolated from Adipose Tissue. Eur Heart J suppl august 2004, International Congress of
European Society of Cardiology Munich 28 august-2 september 2004, e-poster
R Madonna, M Massaro, P Di Napoli, A Grilli, M Felaco, Y-J Geng R De Caterina: Inhibition of 3-HMG-CoA reductase
attenuates the expression of inducible nitric oxide synthase in cardiac myocytes – A link to myocardial protection
during ischemia-reperfusion. Eur Heart J suppl august 2004, International Congress of European Society of Cardiology
Munich 28 august-2 september 2004, e-poster
R Madonna, R De Caterina, M J Wassler, YJ Geng: Telomerase activity and expression in adipose tissue-derived
stromal cells – Evidences for the existence of a more juvanile phenotype in adipose tissue. Eur Heart J suppl august
2004, International Congress of European Society of Cardiology Munich 28 august-2 september 2004, e-poster
R Madonna, R De Caterina, J T Willerson, YJ Geng: Adult Mesenchymal Stem Cells Derived from Adipose Tissue Highly
Express Telomerase and Spontaneously Differentiate into Contractile Cardiomyocytes and Mature endothelial cells.
Hematologica suppl October 2004, Congresso Nazionale della Società Italiana per lo Studio della Trombosi ed
Emostasi, Roma 30 settembre-3 ottobre, oral communication.
R Madonna, M Massaro, P Di Napoli, A Grilli, M Felaco, Y-J Geng R De Caterina: Inhibition of 3-HMG-CoA reductase
attenuates the expression of inducible nitric oxide synthase in cardiac myocytes – A link to myocardial protection
during ischemia-reperfusion. Hematologica suppl October 2004, Congresso Nazionale della Società Italiana per lo
Studio della Trombosi ed Emostasi, Roma 30 settembre-3 ottobre, oral communication.
R Madonna, Li S, Lin J, Rajabi M, Wassler M J, R De Caterina, Geng Y-J: Expression of nitric oxide synthase during
differentiation of telomerase-expressing endothelial cell progenitor derived from adipose tissue. 65° Congresso
Nazionale della Società Italiana di Cardiologia, 11-15 december 2004 Roma Italy. Oral communication.
R Madonna, R De Caterina, J T Willerson, YJ Geng: Cardiomyogenic development of telomerase-expressing
mesenchymal stem cells from adult adipose tissue. 65° Congresso Nazionale della Società Italiana di Cardiologia, 11-15
december 2004 Roma Italy. Oral communication.
R Madonna, M Massaro, P Di Napoli, A Grilli, M Felaco, A De Caterina, D Tang, Y-J Geng, R De Caterina: Statins
enhance differentiation of embryonic stem cells into cardiac myocytes and provide resistance against oxidative stress
- A link to the myocardial protection durino ischemia-reperfusion. 65° Congresso Nazionale della Società Italiana di
Cardiologia, 11-15 december 2004 Roma Italy. Oral communication.
Linee di Ricerca seguite:
Progetti di ricerca pre-dottorato:
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Genetic epidemiology of coronary artery disease − related polymorphisms, including lipoprotein lipase Hind III, PVU II,
SER447-TER,
angiotensin
converting
enzyme
(insertion/deletion)
and
angiotensin
receptor
A1166C,
methilenetetrahidropholate reductase (C677-T), endothelial nitric oxide synthase (Glu298-Asp) and p22phox C242-T;
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In vivo study of the neuroprotective action of hypoxanthine − derivative AIT-082 in NMDA-induced rat striatal and
hippocampal lesions.
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Ex vivo study of inducible nitric oxide synthase (iNOS) expression in ischemic − reperfused rat myocardium, treated with
simvastatin, verapamil and adenosine.
Durante il dottorato di ricerca:
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In vitro study of the effects of insulin, glucose and advanced glicosylation products (AGEs) on the endothelial expression of
intercellular adhesion molecule-1 (ICAM-1), vascular cell adhesion molecule-1 (VCAM-1) ed E-selectin.
In vitro study of the effects of HMG CoA-reductase inhibition on the expression of inducibile nitric oxide synthase
(iNOS) in rat cultured cardiomyocytes.
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In vitro study of the expression of endothelial nitric oxide synthase in insulin − sensitive and insulin − resistants (with
insulin substrate receptor G972R mutation) fibroblasts and HUVEC.
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In vitro study of the effects of HMG CoA-reductase inhibition by simvastatin on the endothelial expression of intercellular
adhesion molecule-1 (ICAM-1), vascular cell adhesion molecule-1 (VCAM-1) ed E-selectin.
Durante il research fellowship negli Stati Uniti
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in vitro study of adult and embryonic stem cell differentiation and proliferation with cardiovascular in vivo applications.
ESPERIENZE DI LABORATORIO:
Università di Chieti, Istituto di Cardiologia, Laboratorio di Cardiologia Sperimentale e Colture Cellulari, presso Ospedale S.
Camillo de Lellis-Chieti (Supervisore: Prof. Raffaele De Caterina)
Basic laboratory techniques; handling and use of laboratory animals (rats, mice); isolation of smooth muscles cells and endothelial
cells from human umbilical cord, cell culture of endothelial cells, fibroblasts, smooth muscle cells, cardiomyocytes and
cardiomyoblasts; spectrophotometric assays, affinity chromatography; cell surface enzyme immunoassays (EIA), cell adhesion
assay, ELISA; Study of genetic polymorphisms by PCR and restriction fragment analysis; Radiometric assays of nitric oxide
synthases; Colorimetric assay of nitrate and nitrite. Molecular biology techniques: DNA and RNA extractions, gel
electrophoresis, Southern blotting, Western blotting, radioactive and chemiluminescent
Northern Blotting, reversetranscriptase-PCR, real-time-PCR, long-PCR, primer design, SDS-PAGE, Immunoblotting, in situ hybridization; elettrophoretic
mobility shift assay. Immunocytochemistry, Immunohistochemistry, direct and indirect immunofluorescence; Flow cytometry,
flow cell sorting; Confocal microscopy.
University fo Texas Medical School and Texas Heart Institute at Houston, TX, Dept. of Internal Medicine, Heart Failure
laboratory (Supervisore: Prof. Yong-Jian Geng)
Embryonic stem cells, bone marrow stem cells, adipose-derived stem cells; Preparation of red-green fluorescent protein
expressing adult and embryonic stem cells; Genetic engeeniring and gene therapy through bacterial tranfection of adult and
embryonic stem cells and mammalian somatic cell lines; Genetic engeeniring and gene therapy through adenoviral transfections of
adult stem cells and mammalian somatic cell lines; lipo-tranfesction and electroporetion; cloning and sub-cloning; Telomerase
activity assay (TRAP); Terminal restriction fragment (TRF) analysis; Langendorff perfusion system and working heart
preparation.
Lingue conosciute: Italiano, Inglese, Francese, comprensione dello Spagnolo
Most relevant publications:
ABSTRACTS:
1.
M Soccio, T Giacchetti, R Madonna, F Romanazzi, A Di Crecchio, P Di Napoli, S Gallina, A M Calafiore, A Barsotti:
Coronary Artery Disease and PVUII Polymorphism of the Lipoprotein Lipasi Gene. JACC 1998, 31 suppl C.
2. M Soccio, R Madonna, A Taccardi, G Vianale, P Di Napoli, M Zimarino, S Gallina, A Procopio, A M Calafiore, A Barsotti:
Genetic polymorphism (C677T) of methylenetetrahydrofolate reductase gene and coronary heart disease. Int Med Clin
Lab 1999, 7 suppl 1-39.
3. M Soccio, R Madonna, G D’Apolito, G Vianale, P Di Napoli, M Zimarino, S Gallina, A Procopio, A M Calafiore, A Barsotti:
Effect of endothelial nitric oxide sinthase gene polymorphism on acute ischemic heart disease. Int Med Clin Lab 1999,
7 suppl 1-38.
4. M. Soccio, R. Madonna, S. Gallina, AM. Calafiore, A. Barsotti, R. De Caterina: A protective effect of the C242T of
P22PHOX from coronary artery disease. Eur Heart J 2000, 21: S276.
5. M Massaro, A Zampolli, R Madonna, MA Carluccio, C Storelli, R De Caterina: Statins inhibits cyclo-oxygenase-2 protein
and activity in human endothelial cells. Possible contributing to plaque stability. Circulation 2002 november suppl P113871
6. R Madonna, P Di Napoli, A Grilli, M Felaco, Y-J Geng, R De Caterina. Inhibition of 3-hydroxy-3-methylglutaryl
coenzyme A reductase attenuates expression of inducible nitric oxide synthase in cardiac myoblasts FASEB J 2003;
17: 165.16
7. R Madonna, A Pandolfi, M Massaro, A Consoli, R De Caterina: insulin enhances vascular cell adhesion molecule (VCAM-1)
expression in human cultured endothelial cells. A link to the pathogenesis of accelerated atherosclerosis in diabetes.
Journal of American College of Cardiology 2004, march 3 vol. 43 suppl A 1106-182
8. Li S, Lin J, Lenhean E, Rajabi M, Madonna R, Rosales C, Willerson J T, Geng Y-J: Cardiac response to intracoronarydelivered stem cells in apolipoprotein-null mice: assessment by Langendorff perfusion. Journal of American College of
Cardiology 2004, march 3 vol. 43 suppl A 1011-108
9. Lin J, Li S, Lenhean E, Rajabi M, Madonna R, Rosales C, Willerson J T, Geng Y-J: Ischemic preconditioning improves
performance of the hearts with coronary delivery of embryonic stem cells: assessment by a Langendorff perfusion
model.
Journal of American College of Cardiology 2004, march 3 vol. 43 suppl A 1068-127
10. Madonna R, Li S, Lin J, Rajabi M, Wassler M J, Geng Y-J: Isolation and characterization of undifferentiated
endothelial cell progenitors from murine adipose tissue. FASEB J 2004; 17: 165.16
11. R Madonna, R De Caterina, J T Willerson, YJ Geng: Adult Mesenchymal Stem Cells Derived from Adipose Tissue Highly
Express Telomerase and Spontaneously Differentiate into Contractile Cardiomyocytes and Mature endothelial cells.
Diabetologia suppl. September 2004;
11. R Madonna, Li S, Lin J, Rajabi M, Wassler M J, R De Caterina, Geng Y-J: Characterization and Heart Trasfusion of
Endothelial Progenitor Cells isolated from Adipose Tissue. Eur Heart J suppl august 2004
12. R Madonna, R De Caterina, M J Wassler, YJ Geng: Telomerase activity and expression in adipose tissue-derived
stromal cells – Evidences for the existence of a more juvanile phenotype in adipose tissue. Eur Heart J suppl august
2004
13. E P Perin, G V Silva, J A Assad, R Madonna, A L Souza, R Majano, A Civitello, J Feldman, J Ober, W K Vaughn, R V
Branco, E M Oliveira, L Carvahlo, Y J Geng: Sirolimus-Eluting stent (SES) inhibits growth factor expression and cell
proliferation without worsening endothelial function in a pig coronary restenosis model. Circulation 2004, 110: 2870
BOOK CHAPTERS:
1. Madonna, G Torge, P Di Napoli, R De Caterina: La “Sindrome” da basse HDL. In: "I Fattori di Rischio cardiovascolare”,
Editori: A. L’Abbate e R. De Caterina, Edizioni: “I quaderni del CNR”, Pisa
2. A Zampolli, R Madonna, R De Caterina: Altri fattori di rischio. In: "I Fattori di Rischio cardiovascolare”, Editori: A.
L’Abbate e R. De Caterina, Edizioni: “I quaderni del CNR”, Pisa;
IN EXTENSU PUBLICATIONS
1.
Soccio, S Gallina, R Madonna, P Di Napoli, A Barsotti: Apoliproprotein gene abnormalities: molecular basis of coronary
heart disease susceptibility. Int Med Clin Lab 1999, 7 suppl 1: S34-S37.
2. R De Caterina, G Basta, R Madonna, D Statile, M Zimarino, S Gallina, A D Procopio: Endothelial cell transfections: a way
for studying promoter activity of genes involved in atherogenesis. Ital Heart J 2000, 1 suppl 3: S55-58.
3. De Caterina, R Madonna, J Hassan, A Procopio: Nutrient and gene expression. World Rev Nutr Diet 2001; 89: 23-52
4. R De Caterina, R Madonna: Antiarrhythmic effects of omega-3 fatty acids. A review. Ital Heart J. 2002 Mar;3(3
Suppl):297-30
5. R De Caterina, R Madonna, R Zucchi, M T La Rovere: Antiarrhythmic effects of omega-3 fatty acids: from
epidemiology to bedside. Am Heart J 2003: 146, 200-2215
6. R Madonna, A Pandolfi, M Massaro, A Consoli, R De Caterina: Insulin enhances vascular cell adhesion molecule (VCAM-1)
expression in human cultured endothelial cells through the prevalence of a pro-atherogenic p38MAP-kinase-mediated
pathway. Diabetologia 2004; Mar 47 (3): 532-6
7. De Caterina R, Zampolli A, Madonna R, Fioretti P, Vanuzzo D: New cardiovascular risk factor: homocysteine and
vitamins involved in homocysteine metabolism. Ital Heart J 2004, Suppl 6: 19S-24S
8. De Caterina R, Madonna R, Massaro M: Effects of omega-3- fatty acids on cytokines and adhesion molecules. Curr
Atheroscl Rep, 2004 6: 485-491
9. De Caterina R, Madonna R: Nutrients and gene expression. World Rev Nutr Diet 2004, 93: 99-133.
10. R Madonna, P Di Napoli, M Massaro, A Grilli, M Felaco, A De Caterina, T Daming, R De Caterina, YJ Geng: Statin
inhibition of 4-hydroxy-3-methyl glutaryl Coenzyme A (HMG CoA) reductase attenuates expression of cytokineinducible nitric oxide synthase in embryonic cardiac myoblasts. Journal of Biology and Chemistry, manoscritto
sottomesso, in revisione
11. R Madonna, J T Willerson, YJ Geng: Adult mesenchymal stem cells derived from adipose tissue highly express
telomerase and spontaneously differentiate into contractile cardiomyocytes. Manoscritto sottomesso
12.
R Madonna, Li S, Lin J, Rajabi M, Wassler M J, Geng YJ: Expression of nitric oxide synthase during differentiation
of telomerase expressing endothelial cells progenitor derived from adipose tissue. Manoscritto sottomesso.
13. E P Perin, G V Silva, J A Assad, R Madonna, A L Souza, R Majano, A Civitello, J Feldman, J Ober, W K Vaughn, R V
Branco, E M Oliveira, L Carvahlo, Y J Geng: Sirolimus-Eluting stent (SES) inhibits growth factor expression and cell
proliferation without worsening endothelial function in a pig coronary restenosis model. Circulation, manoscritto
sottomesso in revisione.