Hemorrhage Lysis Endpoint Coagulation Sequence

HET-CAM BRD: Appendix H2
March 2006
HET-CAM Test Scores for Imidazole
Sequence
Number
186
190
194
214
220
269
270
274
278
281
5A
7A-9A
12A
13
14
Hemorrhage
Endpoint Score
Lysis Endpoint
Score
Coagulation
Endpoint Score
In vitro score
Egg 1 Egg 2 Egg 3 Egg 1 Egg 2 Egg 3 Egg 1 Egg 2 Egg 3 Egg 1 Egg 2 Egg 3
3.40
4.92
4.03
4.03
4.30
4.03
4.13
4.18
4.67
4.57
4.85
4.93
4.92
4.92
4.78
4.83
4.92
4.45
3.88
4.48
4.02
3.88
4.20
4.68
4.57
4.88
4.95
4.93
4.95
4.77
4.83
4.88
4.32
3.95
4.25
3.47
4.00
4.37
4.45
4.55
4.90
4.95
4.93
4.92
4.73
6.84
6.93
6.70
6.88
6.95
6.95
6.67
6.77
6.88
6.93
6.58
6.84
6.81
6.84
6.88
6.84
6.93
6.81
6.88
6.79
6.91
6.72
6.86
6.93
6.91
6.65
6.88
6.84
6.91
6.84
H-9
6.79
6.88
6.84
6.91
6.88
6.91
6.81
6.86
6.93
6.93
6.74
6.88
6.79
6.81
6.88
8.31
8.73
8.85
8.76
8.79
8.73
8.25
8.52
8.76
8.76
8.85
8.55
8.61
8.40
8.85
8.43
8.79
8.85
8.73
8.58
8.70
8.22
8.52
8.79
8.73
8.88
8.43
8.55
8.76
8.73
8.46
8.70
8.88
8.79
8.76
8.76
8.46
8.58
8.82
8.76
8.91
8.49
8.46
8.55
8.85
18.55
20.58
19.58
19.67
20.04
19.71
19.05
19.47
20.31
20.26
20.28
20.32
20.34
20.16
20.51
20.10
20.64
20.11
19.49
19.85
19.63
18.82
19.58
20.40
20.21
20.41
20.26
20.32
20.62
20.34
20.08
20.46
20.04
19.65
19.89
19.14
19.27
19.81
20.20
20.24
20.55
20.32
20.18
20.28
20.46