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Balls et al. (1995) Data Sorted By Substance
IRE BRD: Appendix C1 Substance Acetone Acetone Acetone Acetone Ammonium nitrate Ammonium nitrate Ammonium nitrate Ammonium nitrate L-Aspartic acid L-Aspartic acid L-Aspartic acid L-Aspartic acid Benzalkonium chloride (10%) Benzalkonium chloride (10%) Benzalkonium chloride (10%) Benzalkonium chloride (10%) Benzalkonium chloride (5%) Benzalkonium chloride (5%) Benzalkonium chloride (5%) Benzalkonium chloride (5%) Benzalkonium chloride (1 %) Benzalkonium chloride (1 %) Benzalkonium chloride (1 %) Benzalkonium chloride (1 %) Butyl acetate Butyl acetate Butyl acetate Butyl acetate g-Butyrolactone g-Butyrolactone g-Butyrolactone g-Butyrolactone Captan 90 concentrate Captan 90 concentrate Captan 90 concentrate Captan 90 concentrate 4-Carboxybenzaldehyde Balls et al. (1995) Data Sorted By Substance CASRN Form Tested Testing Lab 67-64-1 67-64-1 67-64-1 67-64-1 6484-52-2 6484-52-2 6484-52-2 6484-52-2 70-47-3 70-47-3 70-47-3 70-47-3 8001-54-5 8001-54-5 8001-54-5 8001-54-5 8001-54-5 8001-54-5 8001-54-5 8001-54-5 8001-54-5 8001-54-5 8001-54-5 8001-54-5 123-86-4 123-86-4 123-86-4 123-86-4 96-48-0 96-48-0 96-48-0 96-48-0 133-06-2 133-06-2 133-06-2 133-06-2 619-66-9 Liquid Liquid Liquid Liquid Solid Solid Solid Solid Solid Solid Solid Solid Solution Solution Solution Solution Solution Solution Solution Solution Solution Solution Solution Solution Liquid Liquid Liquid Liquid Liquid Liquid Liquid Liquid Solid Solid Solid Solid Solid IREA 26 IREA 23 IREA 28 IREA 29 IREA 26 IREA 23 IREA 28 IREA 29 IREA 26 IREA 23 IREA 28 IREA 29 IREA 26 IREA 23 IREA 28 IREA 29 IREA 26 IREA 23 IREA 28 IREA 29 IREA 26 IREA 23 IREA 28 IREA 29 IREA 26 IREA 23 IREA 28 IREA 29 IREA 26 IREA 23 IREA 28 IREA 29 IREA 26 IREA 23 IREA 28 IREA 29 IREA 26 March 2006 Opacity Swelling 1 Hr 4 Hr 1 Hr 4 Hr 3 3 3.7 2 0 0 0 0 0 0 0 1 2 2 1 1.7 2 2 0 1.3 1 2 0.7 0 0 0 0 0 1 0 0 0 2 0 0 1 0 2 2 0.2 0 0 0 0 0 0 0 0 1 3 3 2 2 2 2.7 1.3 1 0 0 0 0 0 0 0.7 0.7 3 2 1 0.7 2 1.7 0 0.3 0 10 32.6 5.5 13 10 3 9.1 7 5 0 9.2 6 20 41.7 24 60 29.2 21.5 27.6 51 20.8 18.8 24.8 31 0 9.4 5.8 11 19.3 27.4 20 19 0 12 8.9 5 5 25 76.3 11.3 15 25 3 12.7 0 5 0 15.3 4 80 62.9 37.4 112 66.4 115.6 114.9 100 20.8 61.7 47.8 81 5 29.1 7.8 17 29.1 49.6 30.6 44 10 31.6 13.4 20 5 C-5 In Vitro Overall In Irritancy Vitro Irritancy Classification Classification Severe Severe Severe Nonsevere Nonsevere Severe Nonsevere Nonsevere Nonsevere Nonsevere Nonsevere Nonsevere Nonsevere Nonsevere Nonsevere Severe Severe Severe Severe Severe Severe Severe Severe Severe Severe Severe Severe Severe Severe Severe Nonsevere Nonsevere Severe Nonsevere Nonsevere Severe Severe Severe Severe Severe Nonsevere Nonsevere Severe Nonsevere Nonsevere Nonsevere Nonsevere IRE BRD: Appendix C1 Balls et al. (1995) Data Sorted By Substance Substance CASRN Form Tested Testing Lab 4-Carboxybenzaldehyde 4-Carboxybenzaldehyde 4-Carboxybenzaldehyde Cetylpyridinium bromide (10%) Cetylpyridinium bromide (10%) Cetylpyridinium bromide (10%) Cetylpyridinium bromide (10%) Cetylpyridinium bromide (6%) Cetylpyridinium bromide (6%) Cetylpyridinium bromide (6%) Cetylpyridinium bromide (6%) Cetylpyridinium bromide (0.1%) Cetylpyridinium bromide (0.1%) Cetylpyridinium bromide (0.1%) Cetylpyridinium bromide (0.1%) Chlorhexidine Chlorhexidine Chlorhexidine Chlorhexidine Cyclohexanol Cyclohexanol Cyclohexanol Cyclohexanol Dibenzoyl-L-tartaric acid Dibenzoyl-L-tartaric acid Dibenzoyl-L-tartaric acid Dibenzoyl-L-tartaric acid Dibenzyl phosphate Dibenzyl phosphate Dibenzyl phosphate Dibenzyl phosphate 2,6-Dichlorobenzoyl chloride 2,6-Dichlorobenzoyl chloride 2,6-Dichlorobenzoyl chloride 2,6-Dichlorobenzoyl chloride 2,2-Dimethylbutanoic acid 2,2-Dimethylbutanoic acid 619-66-9 619-66-9 619-66-9 140-72-7 140-72-7 140-72-7 140-72-7 140-72-7 140-72-7 140-72-7 140-72-7 140-72-7 140-72-7 140-72-7 140-72-7 55-56-1 55-56-1 55-56-1 55-56-1 108-93-0 108-93-0 108-93-0 108-93-0 2743-38-6 2743-38-6 2743-38-6 2743-38-6 1623-08-1 1623-08-1 1623-08-1 1623-08-1 4659-45-4 4659-45-4 4659-45-4 4659-45-4 595-37-9 595-37-9 Solid Solid Solid Solution Solution Solution Solution Solution Solution Solution Solution Solution Solution Solution Solution Solid Solid Solid Solid Liquid Liquid Liquid Liquid Solid Solid Solid Solid Solid Solid Solid Solid Liquid Liquid Liquid Liquid Liquid Liquid IREA 23 IREA 28 IREA 29 IREA 26 IREA 23 IREA 28 IREA 29 IREA 26 IREA 23 IREA 28 IREA 29 IREA 26 IREA 23 IREA 28 IREA 29 IREA 26 IREA 23 IREA 28 IREA 29 IREA 26 IREA 23 IREA 28 IREA 29 IREA 26 IREA 23 IREA 28 IREA 29 IREA 26 IREA 23 IREA 28 IREA 29 IREA 26 IREA 23 IREA 28 IREA 29 IREA 26 IREA 23 March 2006 Opacity Swelling 1 Hr 4 Hr 1 Hr 4 Hr 0 0 1 1 2 0 0.33 1 0 0.3 1 0 0 0 0 3 0 1 1 2 0 1 1.33 3 0 0 1 1 0 0 1 1 0 1 1 3 3 0 0.7 1 2 3 1 0.7 2 2.7 1.3 1 0 0 0 0 4 2 2.7 2 3 2 2 3 3 2.3 0.3 2 1 2 1 0.3 2.3 2 2.3 1 3 3 11.1 2.8 6 23.7 23 11.7 13 30 28.1 13.6 14 24.2 14.9 8.6 11 * 19.4 17 44 13.8 18.4 29 36 50 5.9 11.8 5 5.1 7.4 14.6 11 3.3 21.6 5.2 4 29.8 41.5 25.6 13.2 8 31.6 87.4 30.1 25 30 46.7 26.3 25 25 30.6 8.6 15 * 37.8 54.7 115 68.1 60.3 103 97 50 13.3 16.7 18 5.1 25.9 20.8 14 9.9 36.3 24.2 14 45.6 72.6 C-6 In Vitro Overall In Irritancy Vitro Irritancy Classification Classification Severe Nonsevere Nonsevere Severe Severe Severe Severe Severe Severe Severe Severe Severe Severe Severe Severe Severe Nonsevere Nonsevere Severe Severe Severe Severe Severe Severe Severe Severe Severe Severe Severe Nonsevere Nonsevere Nonsevere Nonsevere Nonsevere Nonsevere Severe Nonsevere Nonsevere Nonsevere Nonsevere Severe Nonsevere Nonsevere Severe Severe Severe IRE BRD: Appendix C1 Substance 2,2-Dimethylbutanoic acid 2,2-Dimethylbutanoic acid 2,5-Dimethylhexanediol 2,5-Dimethylhexanediol 2,5-Dimethylhexanediol 2,5-Dimethylhexanediol Ethanol Ethanol Ethanol Ethanol Ethyl acetate Ethyl acetate Ethyl acetate Ethyl acetate 2-Ethyl-1-hexanol 2-Ethyl-1-hexanol 2-Ethyl-1-hexanol 2-Ethyl-1-hexanol Ethyl-2-methylacetoacetate Ethyl-2-methylacetoacetate Ethyl-2-methylacetoacetate Ethyl-2-methylacetoacetate Ethyl trimethyl acetate Ethyl trimethyl acetate Ethyl trimethyl acetate Ethyl trimethyl acetate Fomesafen Fomesafen Fomesafen Fomesafen Glycerol Glycerol Glycerol Glycerol n-Hexanol n-Hexanol n-Hexanol Balls et al. (1995) Data Sorted By Substance CASRN Form Tested Testing Lab 595-37-9 595-37-9 110-03-2 110-03-2 110-03-2 110-03-2 64-17-5 64-17-5 64-17-5 64-17-5 141-78-6 141-78-6 141-78-6 141-78-6 104-76-7 104-76-7 104-76-7 104-76-7 609-14-3 609-14-3 609-14-3 609-14-3 3938-95-2 3938-95-2 3938-95-2 3938-95-2 72128-02-0 72128-02-0 72128-02-0 72128-02-0 56-81-5 56-81-5 56-81-5 56-81-5 111-27-3 111-27-3 111-27-3 Liquid Liquid Solid Solid Solid Solid Liquid Liquid Liquid Liquid Liquid Liquid Liquid Liquid Liquid Liquid Liquid Liquid Liquid Liquid Liquid Liquid Liquid Liquid Liquid Liquid Solid Solid Solid Solid Liquid Liquid Liquid Liquid Liquid Liquid Liquid IREA 28 IREA 29 IREA 26 IREA 23 IREA 28 IREA 29 IREA 26 IREA 23 IREA 28 IREA 29 IREA 26 IREA 23 IREA 28 IREA 29 IREA 26 IREA 23 IREA 28 IREA 29 IREA 26 IREA 23 IREA 28 IREA 29 IREA 26 IREA 23 IREA 28 IREA 29 IREA 26 IREA 23 IREA 28 IREA 29 IREA 26 IREA 23 IREA 28 IREA 29 IREA 26 IREA 23 IREA 28 March 2006 Opacity Swelling 1 Hr 4 Hr 1 Hr 4 Hr 3 2 1 0 0 0.33 2 1 1.2 2.67 0 0 0 0 1 0 0 0 0 1 0 0.67 0 0 0 0 3 0 0 0.33 0 0 0 0 1.3 0 0 2.3 2.7 1 0 0 0.7 3 3 2.3 2 2 2 0.7 1 1 1 1.7 2 1 2.7 2 1 1 2 0.3 0 3 1.7 0 0 1 0 0.3 0 2 3 2.7 34 29 35 10.3 5.9 10 50 14.2 17.8 25 6.5 18 19.8 14 16.7 5.9 8.3 12 2.5 25.2 25.5 12 5.3 14.3 2.9 4 25 2.3 5.5 4 9.2 5.2 11.3 5 20.5 13.7 19.1 76 78 35 14 11.8 5 60.8 48.5 41 60 13.7 45.1 38.7 25 16.7 20.7 24.7 19 5 29.4 36.5 14 10.5 19.3 13.3 5 25 29.3 12 -1 10 5.2 11.3 4 38.5 43.6 62.1 C-7 In Vitro Overall In Irritancy Vitro Irritancy Classification Classification Severe Severe Severe Nonsevere Nonsevere Nonsevere Nonsevere Severe Severe Severe Severe Severe Nonsevere Severe Severe Severe Severe Nonsevere Nonsevere Nonsevere Nonsevere Nonsevere Nonsevere Severe Severe Severe Nonsevere Nonsevere Nonsevere Nonsevere Nonsevere Nonsevere Severe Severe Severe Nonsevere Nonsevere Nonsevere Nonsevere Nonsevere Nonsevere Nonsevere Severe Severe Severe Severe IRE BRD: Appendix C1 Substance n-Hexanol Imidazole Imidazole Imidazole Imidazole iso-Butanol iso-Butanol iso-Butanol iso-Butanol iso-Propanol iso-Propanol iso-Propanol iso-Propanol Maneb Maneb Maneb Maneb Methyl acetate Methyl acetate Methyl acetate Methyl acetate Methyl cyanoacetate Methyl cyanoacetate Methyl cyanoacetate Methyl cyanoacetate Methylcyclopentane Methylcyclopentane Methylcyclopentane Methylcyclopentane Methyl ethyl ketone Methyl ethyl ketone Methyl ethyl ketone Methyl ethyl ketone Methyl isobutyl ketone Methyl isobutyl ketone Methyl isobutyl ketone Methyl isobutyl ketone Balls et al. (1995) Data Sorted By Substance CASRN Form Tested Testing Lab 111-27-3 288-32-4 288-32-4 288-32-4 288-32-4 78-83-1 78-83-1 78-83-1 78-83-1 67-63-0 67-63-0 67-63-0 67-63-0 12427-38-2 12427-38-2 12427-38-2 12427-38-2 79-20-9 79-20-9 79-20-9 79-20-9 105-34-0 105-34-0 105-34-0 105-34-0 96-37-7 96-37-7 96-37-7 96-37-7 78-93-3 78-93-3 78-93-3 78-93-3 108-10-1 108-10-1 108-10-1 108-10-1 Liquid Solid Solid Solid Solid Liquid Liquid Liquid Liquid Liquid Liquid Liquid Liquid Solid Solid Solid Solid Liquid Liquid Liquid Liquid Liquid Liquid Liquid Liquid Liquid Liquid Liquid Liquid Liquid Liquid Liquid Liquid Liquid Liquid Liquid Liquid IREA 29 IREA 26 IREA 23 IREA 28 IREA 29 IREA 26 IREA 23 IREA 28 IREA 29 IREA 26 IREA 23 IREA 28 IREA 29 IREA 26 IREA 23 IREA 28 IREA 29 IREA 26 IREA 23 IREA 28 IREA 29 IREA 26 IREA 23 IREA 28 IREA 29 IREA 26 IREA 23 IREA 28 IREA 29 IREA 26 IREA 23 IREA 28 IREA 29 IREA 26 IREA 23 IREA 28 IREA 29 March 2006 Opacity Swelling 1 Hr 4 Hr 1 Hr 4 Hr 1.33 2 3 3 2 2 0 2 1.33 1.7 2 0 1.67 3 0 1 0 1 0 1 0 0 0 0 0.33 0 0 0 0 2 1 0 0.67 1 0 0 0 3 3 3 3 2 3 2 3 2 3 2.3 0.7 1.7 2 2 0 0 3 0 1.7 1.7 0 2 0.3 0.3 0 0 0 0 3 2 2.3 2.3 2 3 1.3 0 21 50 45.5 45.8 38 20 14.5 26 40 4 30.9 13.1 16 49.2 29.9 10.8 6 21 12 12.2 15 5.1 5.8 2.9 6 7.4 17.6 2.8 5 20.8 20.7 29.4 14 34.5 29.3 0 9 49 80 75.8 63.2 80 85 47 78.9 91 22.4 65.5 23.4 32 52.5 37.3 16.5 0 49.6 18.8 28.1 26 5.1 8.7 6.8 7 7.4 21 5.6 4 91.7 56.3 51 46 40.4 64.6 8.7 23 C-8 In Vitro Overall In Irritancy Vitro Irritancy Classification Classification Severe Severe Severe Severe Severe Severe Severe Severe Severe Severe Severe Severe Severe Severe Nonsevere Severe Severe Severe Severe Nonsevere Nonsevere Severe Severe Nonsevere Severe Severe Nonsevere Nonsevere Nonsevere Nonsevere Nonsevere Nonsevere Nonsevere Nonsevere Nonsevere Nonsevere Severe Severe Severe Severe Severe Severe Severe Severe Nonsevere Nonsevere IRE BRD: Appendix C1 Balls et al. (1995) Data Sorted By Substance Substance CASRN Form Tested Testing Lab 1-Naphthalene acetic acid 1-Naphthalene acetic acid 1-Naphthalene acetic acid 1-Naphthalene acetic acid 1-Naphthalene acetic acid, Na salt 1-Naphthalene acetic acid, Na salt 1-Naphthalene acetic acid, Na salt 1-Naphthalene acetic acid, Na salt n-Octanol n-Octanol n-Octanol n-Octanol p-Fluoraniline p-Fluoraniline p-Fluoraniline p-Fluoraniline Polyethylene glycol 400 Polyethylene glycol 400 Polyethylene glycol 400 Polyethylene glycol 400 Potassium cyanate Potassium cyanate Potassium cyanate Potassium cyanate Promethazine HCl Promethazine HCl Promethazine HCl Promethazine HCl Pyridine Pyridine Pyridine Pyridine Quinacrine Quinacrine Quinacrine Quinacrine Sodium hydroxide (10%) 86-87-3 86-87-3 86-87-3 86-87-3 61-31-4 61-31-4 61-31-4 61-31-4 111-87-5 111-87-5 111-87-5 111-87-5 371-40-4 371-40-4 371-40-4 371-40-4 25322-68-3 25322-68-3 25322-68-3 25322-68-3 590-28-3 590-28-3 590-28-3 590-28-3 58-33-3 58-33-3 58-33-3 58-33-3 110-86-1 110-86-1 110-86-1 110-86-1 69-05-6 69-05-6 69-05-6 69-05-6 1310-73-2 Solid Solid Solid Solid Solid Solid Solid Solid Liquid Liquid Liquid Liquid Liquid Liquid Liquid Liquid Liquid Liquid Liquid Liquid Solid Solid Solid Solid Solid Solid Solid Solid Liquid Liquid Liquid Liquid Solid Solid Solid Solid Solution IREA 26 IREA 23 IREA 28 IREA 29 IREA 26 IREA 23 IREA 28 IREA 29 IREA 26 IREA 23 IREA 28 IREA 29 IREA 26 IREA 23 IREA 28 IREA 29 IREA 26 IREA 23 IREA 28 IREA 29 IREA 26 IREA 23 IREA 28 IREA 29 IREA 26 IREA 23 IREA 28 IREA 29 IREA 26 IREA 23 IREA 28 IREA 29 IREA 26 IREA 23 IREA 28 IREA 29 IREA 26 March 2006 Opacity Swelling 1 Hr 4 Hr 1 Hr 4 Hr 0 0 0 1 2 0 0 2 0 0 0 0 2 0 1.3 1.67 1 0 0 0 0 0 0 0 2 1 1 2 1 2 2 2.33 0 0 0 0 3 0.3 2.3 0 1 3 2.7 3 2 1 2 1.8 1 2 2 3 2.2 1 1 0 0 0 0 0 0 2 3 2.3 2 3 3 3 2.3 0 0 0.7 0 4 15 21.9 1 10 67 16.1 61 84 4.4 17.6 14.2 11 25 27.4 33.7 25 29.4 20.7 6 4 9.1 1.5 5.3 5 17.5 76.1 20.8 62 18.2 10.3 34.9 40 10.5 0 13 5 86 15 24.1 2.8 13 108.7 41.6 125.1 155 14.8 26.1 29.9 16 55 63.7 68.7 70 31.1 27.4 12.8 -1 9.1 1.5 11.5 -1 45 117.1 86.9 110 53.7 48.5 42.4 75 10.5 0.7 16.7 4 110.5 C-9 In Vitro Overall In Irritancy Vitro Irritancy Classification Classification Nonsevere Nonsevere Nonsevere Nonsevere Nonsevere Severe Severe Severe Severe Severe Nonsevere Severe Severe Severe Nonsevere Severe Severe Severe Severe Severe Severe Severe Severe Nonsevere Nonsevere Nonsevere Nonsevere Nonsevere Nonsevere Nonsevere Severe Severe Severe Severe Severe Severe Severe Severe Severe Severe Nonsevere Nonsevere Nonsevere Nonsevere Nonsevere Severe Severe IRE BRD: Appendix C1 Substance Sodium hydroxide (10%) Sodium hydroxide (10%) Sodium hydroxide (10%) Sodium hydroxide (1%) Sodium hydroxide (1%) Sodium hydroxide (1%) Sodium hydroxide (1%) Sodium lauryl sulfate (15 %) Sodium lauryl sulfate (15 %) Sodium lauryl sulfate (15 %) Sodium lauryl sulfate (15 %) Sodium lauryl sulfate (3 %) Sodium lauryl sulfate (3 %) Sodium lauryl sulfate (3 %) Sodium lauryl sulfate (3 %) Sodium oxalate Sodium oxalate Sodium oxalate Sodium oxalate Sodium perborate tetrahydrate Sodium perborate tetrahydrate Sodium perborate tetrahydrate Sodium perborate tetrahydrate tetra-Aminopyrimidine sulfate tetra-Aminopyrimidine sulfate tetra-Aminopyrimidine sulfate tetra-Aminopyrimidine sulfate Thiourea Thiourea Thiourea Thiourea Toluene Toluene Toluene Toluene Trichloroacetic acid (30%) Trichloroacetic acid (30%) Balls et al. (1995) Data Sorted By Substance CASRN Form Tested Testing Lab 1310-73-2 1310-73-2 1310-73-2 1310-73-2 1310-73-2 1310-73-2 1310-73-2 151-21-3 151-21-3 151-21-3 151-21-3 151-21-3 151-21-3 151-21-3 151-21-3 62-76-0 62-76-0 62-76-0 62-76-0 10486-00-7 10486-00-7 10486-00-7 10486-00-7 5392-28-9 5392-28-9 5392-28-9 5392-28-9 62-56-6 62-56-6 62-56-6 62-56-6 108-88-3 108-88-3 108-88-3 108-88-3 76-03-9 76-03-9 Solution Solution Solution Solution Solution Solution Solution Solution Solution Solution Solution Solution Solution Solution Solution Solid Solid Solid Solid Solid Solid Solid Solid Solid Solid Solid Solid Solid Solid Solid Solid Liquid Liquid Liquid Liquid Solution Solution IREA 23 IREA 28 IREA 29 IREA 26 IREA 23 IREA 28 IREA 29 IREA 26 IREA 23 IREA 28 IREA 29 IREA 26 IREA 23 IREA 28 IREA 29 IREA 26 IREA 23 IREA 28 IREA 29 IREA 26 IREA 23 IREA 28 IREA 29 IREA 26 IREA 23 IREA 28 IREA 29 IREA 26 IREA 23 IREA 28 IREA 29 IREA 26 IREA 23 IREA 28 IREA 29 IREA 26 IREA 23 March 2006 Opacity Swelling 1 Hr 4 Hr 1 Hr 4 Hr 3 3.7 2 1.3 0 1 1.67 0 0 0 0.33 0 0 0 0 0 0 0 0 0 0 0 0 2 0 0 1 0 0 0 0 1 0 0.7 1 4 3 4 4 4 2 3 3 3 1 2 0.3 2 1 0 0 1 0 0 0 0 0 0 0 0 1 0 0 2 0 0 0 0.7 1 0 1 0 4 4 107.8 * 111 40 41.7 57.1 62 21.1 13.5 14.5 16 5.3 13.4 8.4 12 5 0.8 17.3 6 5 0.8 2.9 4 12.5 0.7 1 3 10 5.1 5.7 7 28.3 11.1 10.1 8 * 44 144.3 * 160 85 65.2 121.9 102 21.1 26.3 22.3 24 15.8 22.4 9.3 14 5 6.7 22 5 5 2.3 14.7 0 25 4.4 2.9 9 10 5.1 5.7 4 30 37.6 17.5 6 * 100.8 C-10 In Vitro Overall In Irritancy Vitro Irritancy Classification Classification Severe Severe Severe Severe Severe Severe Severe Severe Nonsevere Nonsevere Severe Nonsevere Nonsevere Nonsevere Nonsevere Nonsevere Nonsevere Nonsevere Nonsevere Nonsevere Nonsevere Nonsevere Nonsevere Nonsevere Nonsevere Nonsevere Nonsevere Nonsevere Severe Nonsevere Nonsevere Nonsevere Nonsevere Nonsevere Nonsevere Nonsevere Nonsevere Nonsevere Severe Severe Severe Nonsevere Nonsevere Severe Severe Severe IRE BRD: Appendix C1 Substance Trichloroacetic acid (30%) Trichloroacetic acid (30%) Trichloroacetic acid (3%) Trichloroacetic acid (3%) Trichloroacetic acid (3%) Trichloroacetic acid (3%) Triton X-100 (10 %) Triton X-100 (10 %) Triton X-100 (10 %) Triton X-100 (10 %) Triton X-100 (5 %) Triton X-100 (5 %) Triton X-100 (5 %) Triton X-100 (5 %) Tween 20 Tween 20 Tween 20 Tween 20 Balls et al. (1995) Data Sorted By Substance CASRN Form Tested Testing Lab 76-03-9 76-03-9 76-03-9 76-03-9 76-03-9 76-03-9 9002-93-1 9002-93-1 9002-93-1 9002-93-1 9002-93-1 9002-93-1 9002-93-1 9002-93-1 9005-64-5 9005-64-5 9005-64-5 9005-64-5 Solution Solution Solution Solution Solution Solution Solution Solution Solution Solution Solution Solution Solution Solution Liquid Liquid Liquid Liquid IREA 28 IREA 29 IREA 26 IREA 23 IREA 28 IREA 29 IREA 26 IREA 23 IREA 28 IREA 29 IREA 26 IREA 23 IREA 28 IREA 29 IREA 26 IREA 23 IREA 28 IREA 29 March 2006 Opacity Swelling 1 Hr 4 Hr 1 Hr 4 Hr 3.7 3 0 1 0.7 1 2 0 0 0.67 2 0 0 0.33 0 0 0 0 3.7 3 1 2 0 0 3 2 2 2.3 3 2 1.3 1.5 0 1 0 0 * 4 6 12.1 7.2 7 8.8 24.2 36.2 39 25.4 23.3 10 20 12.6 28.1 6.4 7 * 54 6 36.2 20.6 11 19.2 32.6 95.3 80 31.6 30.1 25.2 45 15.1 29.6 14.7 4 C-11 In Vitro Overall In Irritancy Vitro Irritancy Classification Classification Severe Severe Nonsevere Nonsevere Severe Nonsevere Nonsevere Severe Severe Severe Severe Severe Severe Severe Severe Severe Severe Nonsevere Nonsevere Severe Nonsevere Nonsevere